DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9981 and AT1G68710

DIOPT Version :9

Sequence 1:	NP_001259610.1	Gene:	CG9981 / 32609	FlyBaseID:	FBgn0030746	Length:	1060	Species:	Drosophila melanogaster
Sequence 2:	NP_001320718.1	Gene:	AT1G68710 / 843201	AraportID:	AT1G68710	Length:	1226	Species:	Arabidopsis thaliana

Alignment Length:	1182	Identity:	401/1182 - (33%)
Similarity:	586/1182 - (49%)	Gaps:	208/1182 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 QIGG----------------IESRQQKPLNRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIV 63
            ||||                .:||.... |.|.|||||..||||.:.:|||||...||||:..::
plant    34 QIGGPGFSRVVYCNEPDSPEADSRNYSD-NYVRTTKYTLATFLPKSLFEQFRRVANFYFLVTGVL 97

  Fly    64 SFFVNETISPLV------SLLPLLFVMIITALKEGLEDYSRSKSDKLVNTARVTVIR-NGKEEII 121
            :|      :||.      :::|||||:..|.:|||:||:.|.|.|..||..:|.|.| :|..:..
plant    98 AF------TPLAPYTASSAIVPLLFVIGATMVKEGVEDWRRQKQDNEVNNRKVKVHRGDGSFDAK 156

  Fly   122 NSQFIVPGDLVVVRNDGDVPCDLVLLQSSSADRKCFVNTANLDGETNLKT---ICVPTNYLLAGD 183
            ..:.:..||:|.|..:...|.|||||.||..|..|:|.|.|||||||||.   :.|.::  |..:
plant   157 EWKTLSIGDIVKVEKNEFFPADLVLLSSSYEDAICYVETMNLDGETNLKVKQGLEVTSS--LRDE 219

  Fly   184 HELQGKDCIV-CEPSSADLYTFNGRLELRSGNDGAGSSAGDALPLTIDNLLLRGVRVKSTERVVG 247
            ...:|.:..| ||..:|:||:|.|.:||:          |...||:...||||..::::|:.:.|
plant   220 FNFKGFEAFVKCEDPNANLYSFVGTMELK----------GAKYPLSPQQLLLRDSKLRNTDFIFG 274

  Fly   248 CAIYTGMHTKLQLNSRYTGNKSASSEKYINR---FMVALIVGMIVVVVVLYLIERHKEAKI-VPT 308
            ..|:||..||:..||....:|.:..||.:::   .|..:::.|..:..|::.:....:.|. |..
plant   275 AVIFTGHDTKVIQNSTDPPSKRSMIEKKMDKIIYLMFFMVITMAFIGSVIFGVTTRDDLKDGVMK 339

  Fly   309 MPYQGPPTNFNSAWQIFED-----------FLSFLLLFNYMVPISAYMNIEVYRIFGMHFMHNDL 362
            ..|..|.::     .||.|           ||:.::|::|.:|||.|::||:.::....|::.|:
plant   340 RWYLRPDSS-----SIFFDPKRAPVAAIYHFLTAVMLYSYFIPISLYVSIEIVKVLQSIFINQDI 399

  Fly   363 HLYDEETDQPCRVNASNLNEELGQVNILFSDKTGTLTKNLMKFVNCYVPGTNY------------ 415
            |:|.||.|:|.|...||||||||||:.:.||||||||.|.|:|:.|.|.||.|
plant   400 HMYYEEADKPARARTSNLNEELGQVDTILSDKTGTLTCNSMEFIKCSVAGTAYGRGVTEVEMAMG 464

  Fly   416 ------------------QLQNTHLVSEGTDEKFEL--EKL-------DADAAVL---FEALAVC 450
                              :.....:..|.|.:.|..  |::       :..|.|:   |..||||
plant   465 RRKGGPLVFQSDENDIDMEYSKEAITEESTVKGFNFRDERIMNGNWVTETHADVIQKFFRLLAVC 529

  Fly   451 HTVEVLQEVGDKTLESSESVSEQSHLMSRNIVDRYQASSPDEKALLEGCASLGLVYEGQENDVLS 515
            ||  |:.||.    |.:|.:|             |:|.||||.|.:.....||..:..:....:|
plant   530 HT--VIPEVD----EDTEKIS-------------YEAESPDEAAFVIAARELGFEFFNRTQTTIS 575

  Fly   516 ICRYP--SAEKVQ--FKRLHVLEFSSERQRMSVIVRDQSDTIWLYSKGAESAIFPRCKAS--PLV 574
            :....  |.::|:  :|.|:||||:|.|:||||||:::...:.|..|||::.:|.|...:  ...
plant   576 VRELDLVSGKRVERLYKVLNVLEFNSTRKRMSVIVQEEDGKLLLLCKGADNVMFERLSKNGREFE 640

  Fly   575 EQTDAQITKYAQNGLRTMAVGRRMLTDDELFHFEELYRKANTQLS-NRNELIASCYETVENELDL 638
            |:|...:.:||..||||:.:..|.|.:.|...|.|...:|.:.:| :|..||....|.:|.:|.|
plant   641 EETRDHVNEYADAGLRTLILAYRELDEKEYKVFNERISEAKSSVSADRESLIEEVTEKIEKDLIL 705

  Fly   639 LGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAYNIGLACRHIPRGSKQHFIINTTEP- 702
            |||||:||.||..|.:.::.|..||:|||||||||:|||.|||.||..:.:..|| .|||...|
plant   706 LGATAVEDKLQNGVPDCIDKLAQAGIKIWVLTGDKMETAINIGFACSLLRQDMKQ-IIINLETPE 769

  Fly   703 ---AELLARLDMIGDDEPE---------------------VLIVDGTTIT-ALLEHTPRQFADLA 742
               .|.....|:|.....|                     .||:||.::. ||.:.....|.:||
plant   770 IQSLEKTGEKDVIAKASKENVLSQIINGKTQLKYSGGNAFALIIDGKSLAYALDDDIKHIFLELA 834

  Fly   743 LRCRAVLCCRLSPLQKSEIVTLIKRRKKYITAAIGDGANDVSMIQEAHIGIGITGREGKQAARCA 807
            :.|.:|:|||.||.||:.:..|:|......|.|||||||||.|:|||.||:||:|.||.||...:
plant   835 VSCASVICCRSSPKQKALVTRLVKSGNGKTTLAIGDGANDVGMLQEADIGVGISGVEGMQAVMSS 899

  Fly   808 DFSIARFEMLRRLFLVHGHYNSQRLAFLVLFYCYKNIIITGCMALYQVYDLYSATNVYNSIYLWL 872
            |.:||:|..|.||.|||||:..:|::.::.::.||||.....:.||:.|..:|:|..||..:|.|
plant   900 DIAIAQFRYLERLLLVHGHWCYRRISTMICYFFYKNITFGFTLFLYETYTTFSSTPAYNDWFLSL 964

  Fly   873 FDIVYISFSFTVLAICDKDYSEE---------TLLSHPE------------LYKPLAHNRQASMG 916
            :::.:.|.....|.:.|:|.|..         .|.||..            |..||.:.......
plant   965 YNVFFSSLPVIALGVFDQDVSARYCLKVNITTALSSHQSKNLCQLLPFFLVLQFPLLYQEGVQNV 1029

  Fly   917 VFSL-----WILNGFVQCFIIFFFTYAMLNDANVLFN-GGQTASFQTFGTMLITIIVIVGNLKLL 975
            :||.     |:.|||....||||...:.|.  :..|| .|:|...:..|..:.|.||.|.||::.
plant  1030 LFSWRRILGWMFNGFYSAVIIFFLCKSSLQ--SQAFNHDGKTPGREILGGTMYTCIVWVVNLQMA 1092

  Fly   976 LVAHYMTYRNFAMILASIAA--FMLTTYLYNLYTSGEL--------YDVYNQFLS-SLPIWLFTI 1029
            |...|.|.....:|.:||..  |.:|.|       |||        |.|:.:.|: ||..||.|:
plant  1093 LAISYFTLIQHIVIWSSIVVWYFFITVY-------GELPSRISTGAYKVFVEALAPSLSYWLITL 1150

  Fly  1030 ICSVACLLPDFV 1041
            ...||.|:|.|:
plant  1151 FVVVATLMPYFI 1162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9981	NP_001259610.1	PhoLip_ATPase_N	20..66	CDD:292826	22/45 (49%)
		ATPase-Plipid	28..1051	CDD:273734	395/1153 (34%)
		E1-E2_ATPase	84..>189	CDD:278548	42/108 (39%)
		Cation_ATPase	<489..568	CDD:289987	29/82 (35%)
		HAD_like	<758..807	CDD:304363	26/48 (54%)
		PhoLip_ATPase_C	804..1050	CDD:292829	84/276 (30%)
AT1G68710	NP_001320718.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100089
Panther	1	1.100	-	-	O	PTHR24092
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820