DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9981 and AT1G54280

DIOPT Version :9

Sequence 1:	NP_001259610.1	Gene:	CG9981 / 32609	FlyBaseID:	FBgn0030746	Length:	1060	Species:	Drosophila melanogaster
Sequence 2:	NP_001319223.1	Gene:	AT1G54280 / 841869	AraportID:	AT1G54280	Length:	1240	Species:	Arabidopsis thaliana

Alignment Length:	1143	Identity:	383/1143 - (33%)
Similarity:	561/1143 - (49%)	Gaps:	185/1143 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 NRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIVSFFVNETISPLVSLLPLLFVMIITALKEG 92
            |.|:||:|...||||...||||.|...||||:..|:|.|.....:....:.||:||:.::..||.
plant    62 NYVSTTRYNLLTFLPKCLYEQFHRVANFYFLVAAILSVFPLSPFNKWSMIAPLVFVVGLSMGKEA 126

  Fly    93 LEDYSRSKSDKLVNTARVTVIRNGKEEIINSQF--IVPGDLVVVRNDGDVPCDLVLLQSSSADRK 155
            |||:.|...|..||:.:.:| ..|..:.....:  |..||:|.|..|...|.||:||.||..|..
plant   127 LEDWRRFMQDVEVNSRKASV-HKGSGDFGRRTWKRIRVGDIVRVEKDEFFPADLLLLSSSYEDGI 190

  Fly   156 CFVNTANLDGETNLKT-ICVPTNYLLAGDHELQG-KDCIVCEPSSADLYTFNGRLELRSGNDGAG 218
            |:|.|.|||||||||. .|:.....|..|...|. ...|.||..:.:||||.|.||
plant   191 CYVETMNLDGETNLKVKRCLDATLALEKDESFQNFSGTIKCEDPNPNLYTFVGNLE--------- 246

  Fly   219 SSAGDALPLTIDNLLLRGVRVKSTERVVGCAIYTGMHTKLQLNSRYTGNKSASSEK---YINRFM 280
             ..|...||..:.:|||..::::|..|.|..::||..||:..||..:.:|.:..||   ||...:
plant   247 -CDGQVYPLDPNQILLRDSKLRNTAYVYGVVVFTGHDTKVMQNSTKSPSKRSRIEKRMDYIIYTL 310

  Fly   281 VALI--------VGMIVVVVVL-----YLIERHKEAKIVPTMPYQGPPTNFNSAWQIFEDFLSFL 332
            .||:        :|..|:..:|     ||.....|:...||.|..        ||.:  ..::.|
plant   311 FALLLTVSFISSLGFAVMTKLLMAEWWYLRPDKPESLTNPTNPLY--------AWVV--HLITAL 365

  Fly   333 LLFNYMVPISAYMNIEVYRIFGMHFMHNDLHLYDEETDQPCRVNASNLNEELGQVNILFSDKTGT 397
            ||:.|::|||.|::|||.::...||::.||.|||.|:..|.:...||||||||||:.:.||||||
plant   366 LLYGYLIPISLYVSIEVVKVLQAHFINQDLQLYDSESGTPAQARTSNLNEELGQVDTILSDKTGT 430

  Fly   398 LTKNLMKFVNCYVPGTNYQLQNTHL----------------------------------VSEGTD 428
            ||.|.|.|:.|.:.||:|.::.:.:                                  ::..|.
plant   431 LTCNQMDFLKCSIAGTSYGVRASEVELAAAKQMAMDLEEKGEEVANLSMNKGRTQRYAKLASKTS 495

  Fly   429 EKFELEKL-----------------------------------DADAAVLFEALAVCHTV--EVL 456
            ..||||.:                                   ..|..:.|..||||||.  ||.
plant   496 SDFELETVVTASDEKDQKQNTGVKGFSFEDNRLMNENWLNEPNSDDILMFFRILAVCHTAIPEVD 560

  Fly   457 QEVGDKTLESSESVSEQSHLMSRNIVDRYQASSPDEKALLEGCASLGLVY-EGQENDVLSICRYP 520
            ::.|..|                     |:|.||||.|.|......|..: :..::.|....|:.
plant   561 EDTGMCT---------------------YEAESPDEVAFLVASREFGFEFTKRTQSSVFIAERFS 604

  Fly   521 SAEKV---QFKRLHVLEFSSERQRMSVIVRDQSDTIWLYSKGAESAIFPRCKAS--PLVEQTDAQ 580
            |:.:.   ::|.|::|:|:|:|:|||.||||:...|.|..|||:|.||.|...|  ..:..|...
plant   605 SSGQPVDREYKILNLLDFTSKRKRMSAIVRDEEGQILLLCKGADSIIFERLSKSGKEYLGATSKH 669

  Fly   581 ITKYAQNGLRTMAVGRRMLTDDELFHFEELYRKANTQL-SNRNELIASCYETVENELDLLGATAL 644
            :..|.:.||||:|:|.|.|.:.|...:...:.||.|.: ::|:|::....:.:|.||.|:||||:
plant   670 LNVYGEAGLRTLALGYRKLDETEYAAWNSEFHKAKTSVGADRDEMLEKVSDMMEKELILVGATAV 734

  Fly   645 EDALQEHVGETLEALQAAGLKIWVLTGDKVETAYNIGLACRHIPRGSKQHFIINT-----TEPAE 704
            ||.||:.|.:.::.|..||||||||||||:|||.|||.||..:.:|.||..|..|     ::.:|
plant   735 EDKLQKGVPQCIDNLAQAGLKIWVLTGDKMETAINIGYACSLLRQGMKQISISLTNVEESSQNSE 799

  Fly   705 LLARLDMIG-----------DDEPE---VLIVDGTTIT-ALLEHTPRQFADLALRCRAVLCCRLS 754
            ..|:..::.           :.:|.   .||:||.|:| ||.:....||..||:.|.:|:|||:|
plant   800 AAAKESILMQITNASQMIKIEKDPHAAFALIIDGKTLTYALKDDVKYQFLALAVDCASVICCRVS 864

  Fly   755 PLQKSEIVTLIKRRKKYITAAIGDGANDVSMIQEAHIGIGITGREGKQAARCADFSIARFEMLRR 819
            |.||:.:..|.|......|.|||||||||.|||||.||:||:|.||.||...:|||||:|..|.|
plant   865 PKQKALVTRLAKEGTGKTTLAIGDGANDVGMIQEADIGVGISGVEGMQAVMASDFSIAQFRFLER 929

  Fly   820 LFLVHGHYNSQRLAFLVLFYCYKNIIITGCMALYQVYDLYSATNVYNSIYLWLFDIVYISFSFTV 884
            |.:||||:..:|:|.::.::.||||.....:..::.:..:|..::||..||.||::|..|.....
plant   930 LLVVHGHWCYKRIAQMICYFFYKNITFGLTLFYFECFTGFSGQSIYNDSYLLLFNVVLTSLPVIS 994

  Fly   885 LAICDKDYSEETLLSHPELY----KPLAHNRQASMGVFSLWILNGFVQCFIIF------FFTYAM 939
            |.:.::|...:..|..|.||    |.|..:....:|    |:.||.....:||      |...:.
plant   995 LGVFEQDVPSDVCLQFPALYQQGPKNLFFDWYRILG----WMGNGVYASIVIFTLNLGIFHVQSF 1055

  Fly   940 LNDANVLFNGGQTASFQTFGTMLITIIVIVGNLKLLLVAHYMTYRNFAMILASIAAFMLTTYLYN 1004
            .:|       ||||.....||.:.|.|:...|:::.|...:.|:....||..||.|:.:...||.
plant  1056 RSD-------GQTADMNAMGTAMFTCIIWAVNVQIALTMSHFTWIQHVMIWGSIGAWYVFLALYG 1113

  Fly  1005 LY---TSGELYDVYNQFLSSLPI-WLFTIICSVACLLP 1038
            :.   .||.::.:..:.|:..|| ||.:::...|..||
plant  1114 MLPVKLSGNIFHMLVEILAPAPIFWLTSLLVIAATTLP 1151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9981	NP_001259610.1	PhoLip_ATPase_N	20..66	CDD:292826	20/37 (54%)
		ATPase-Plipid	28..1051	CDD:273734	383/1143 (34%)
		E1-E2_ATPase	84..>189	CDD:278548	41/108 (38%)
		Cation_ATPase	<489..568	CDD:289987	31/82 (38%)
		HAD_like	<758..807	CDD:304363	27/48 (56%)
		PhoLip_ATPase_C	804..1050	CDD:292829	72/249 (29%)
AT1G54280	NP_001319223.1	ATPase-Plipid	59..1172	CDD:273734	383/1143 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100089
Panther	1	1.100	-	-	O	PTHR24092
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820