DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9981 and ECA3

DIOPT Version :9

Sequence 1:	NP_001259610.1	Gene:	CG9981 / 32609	FlyBaseID:	FBgn0030746	Length:	1060	Species:	Drosophila melanogaster
Sequence 2:	NP_563860.1	Gene:	ECA3 / 837550	AraportID:	AT1G10130	Length:	998	Species:	Arabidopsis thaliana

Alignment Length:	1132	Identity:	248/1132 - (21%)
Similarity:	423/1132 - (37%)	Gaps:	309/1132 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 NRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIVSFFV----NETISPLVSLLPLLFVMIITA 88
            |.:...|.|.|..|.|   :||...:....::..||||.:    .||  .|.:.|....:::|.|
plant    39 NVLPEEKRTPFWKLVL---KQFDDLLVKILIVAAIVSFVLALANGET--GLTAFLEPFVILLILA 98

  Fly    89 LKEGLEDYSRSKSDKLVNTAR------VTVIRNGKEEIINSQFIVPGDLVVVRNDGDVPCDLVLL 147
            ....:...:.:.::|.:...|      .||:|||...|:.:..:||||:|.|.....:|.||.::
plant    99 ANAAVGVITETNAEKALEELRAYQANIATVLRNGCFSILPATELVPGDIVEVTVGCKIPADLRMI 163

  Fly   148 QSSSADRKCFVNTANLDGETNLKTICVPTNYLLAGDHELQGKDCIVCEPSSADLYTFNGRLELRS 212
            :.||       ||..:|...                  |.|:.|.|.:.....|.|
plant   164 EMSS-------NTFRVDQAI------------------LTGESCSVEKDVDCTLTT--------- 194

  Fly   213 GNDGAGSSAGDALPLTIDNLLLRGVRV---KSTERVVGCAIYTGM----HTKLQLNSRYTGNKSA 270
                      :|:.....|:|..|..|   :....|:|....|.|    .:.||.:...|..|..
plant   195 ----------NAVYQDKKNILFSGTDVVAGRGRAVVIGVGSNTAMGSIHDSMLQTDDEATPLKKK 249

  Fly   271 SSEKYINRFMVALIVGMIVVVVVLYLIERHKEAKIVPTMPYQGPPTN---FNSAWQIFEDFLSFL 332
            ..|  ...|:..:|.|:.|:|.|:             .:.:...|::   |..|...|:..::..
plant   250 LDE--FGSFLAKVIAGICVLVWVV-------------NIGHFSDPSHGGFFKGAIHYFKIAVALA 299

  Fly   333 LLFNYMVPISAYMNIEVYRIFGMHFMHNDLHLYDEETDQPCRVNASNLN----EELGQVNILFSD 393
            :.   .:|......:......|              |.:..|:||...:    |.||...::.||
plant   300 VA---AIPEGLPAVVTTCLALG--------------TKKMARLNAIVRSLPSVETLGCTTVICSD 347

  Fly   394 KTGTLTKNLMK--------------FVNCY-VPGTNYQLQNTHLVSEGTDEKFELEKLDADAAVL 443
            ||||||.|:|.              .:|.: |.||.|..:.|...|.|    .:|: |.|.:..|
plant   348 KTGTLTTNMMSVSKICVVQSAEHGPMINEFTVSGTTYAPEGTVFDSNG----MQLD-LPAQSPCL 407

  Fly   444 FEALAVCHTV---EVLQEVGDKTLESSESVSEQSHLMSRNIVDRYQASSPDEKALLEGC----AS 501
            .. ||:|.::   .:||...||  :|.|.:.|.:.:..|.:.         ||..|.|.    ::
plant   408 HH-LAMCSSLCNDSILQYNPDK--DSYEKIGESTEVALRVLA---------EKVGLPGFDSMPSA 460

  Fly   502 LGLVYEGQENDVLSICRYPSAEKVQFKRLHVLEFSSERQRMSVIV-RDQSDTIWLYSKGAESAIF 565
            |.::   .:::..|.|.:  ..:.|||:::||||:.:|:.|||:. ..|.|.  ::||||..:|.
plant   461 LNML---SKHERASYCNH--YWENQFKKVYVLEFTRDRKMMSVLCSHKQMDV--MFSKGAPESII 518

  Fly   566 PRCKASPLVEQTDAQITKYAQNG----LRTMAVGRRMLTDDELFHF-EELYRKANTQLSNRNELI 625
            .||             .|...||    :...|.||..| :...:.| :|..|           .:
plant   519 ARC-------------NKILCNGDGSVVPLTAAGRAEL-ESRFYSFGDETLR-----------CL 558

  Fly   626 ASCYETV-----------ENELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAYN 679
            |..::||           ||:|..:|...:.|..:|.|.:.:.|...||:::.|:|||...||.:
plant   559 ALAFKTVPHGQQTISYDNENDLTFIGLVGMLDPPREEVRDAMLACMTAGIRVIVVTGDNKSTAES 623

  Fly   680 IGLACRHIPRGSKQHFIINTTEPAELLARLDMIGDDEPEVLIVDGTTITAL-LEHTPRQFADLAL 743
            :   ||.|                   ...|.:.|       ..|.:.||. .|..|.....|||
plant   624 L---CRKI-------------------GAFDNLVD-------FSGMSYTASEFERLPAVQQTLAL 659

  Fly   744 RCRAVLCCRLSPLQKSEIVTLIKRRKKYITAAIGDGANDVSMIQEAHIGIGITGREGKQAARCAD 808
            | |..|..|:.|..|..:|..::::.: :.|..|||.||...:::|.|||.:  ..|...|:.|.
plant   660 R-RMTLFSRVEPSHKRMLVEALQKQNE-VVAMTGDGVNDAPALKKADIGIAM--GSGTAVAKSAS 720

  Fly   809 FSIARFEMLRRLF--LVHGH--YNSQRLAFLVLFYCYKNIIITGCM---ALYQVYDLYSATNVYN 866
            ..:...:....:.  :..|.  ||:.:.  .:.:....||....|:   |:..:.|..:...:
plant   721 DMVLADDNFASIVAAVAEGRAIYNNTKQ--FIRYMISSNIGEVVCIFVAAVLGIPDTLAPVQL-- 781

  Fly   867 SIYLWLFDIVYISFSFTVLAICDKDYSEETLLSHPELYKPLAHNRQASMGVFSLWI--------- 922
               ||: ::|......|.:....:|  .:.:.:.|         |:....|.:.|:
plant   782 ---LWV-NLVTDGLPATAIGFNKQD--SDVMKAKP---------RKVGEAVVTGWLFFRYLVIGV 831

  Fly   923 ------LNGFVQCFIIFFFTYAMLNDANVLFNGGQTASFQTF-----------------GTMLIT 964
                  :.||     |::|.|   :|........:..:|:|.                 .|:.:|
plant   832 YVGLATVAGF-----IWWFVY---SDGGPKLTYSELMNFETCALRETTYPCSIFEDRHPSTVAMT 888

  Fly   965 IIVIV----------GNLKLLLVAHYMTYRNFAMILASIAAFMLTTYLYNLYTSGELYDVYNQFL 1019
            ::|:|          .|..||::    |.|:...::.||...||...|. ||.. .|..:::...
plant   889 VLVVVEMFNALNNLSENQSLLVI----TPRSNLWLVGSIILTMLLHVLI-LYVH-PLAVLFSVTP 947

  Fly  1020 SSLPIWLFTIICSVACLLPDFVIKVVN 1046
            .|...|...:..|...::.|.::|.::
plant   948 LSWAEWTAVLYLSFPVIIIDELLKFLS 974

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9981	NP_001259610.1	PhoLip_ATPase_N	20..66	CDD:292826	11/37 (30%)
		ATPase-Plipid	28..1051	CDD:273734	248/1132 (22%)
		E1-E2_ATPase	84..>189	CDD:278548	25/110 (23%)
		Cation_ATPase	<489..568	CDD:289987	25/83 (30%)
		HAD_like	<758..807	CDD:304363	14/48 (29%)
		PhoLip_ATPase_C	804..1050	CDD:292829	49/292 (17%)
ECA3	NP_563860.1	Cation_ATPase_N	4..72	CDD:279080	9/35 (26%)
		ATPase-IIA1_Ca	53..975	CDD:273452	243/1118 (22%)
		E1-E2_ATPase	92..336	CDD:278548	60/319 (19%)
		Cation_ATPase	416..524	CDD:289987	35/138 (25%)
		COG4087	<604..>707	CDD:226572	36/133 (27%)
		Cation_ATPase_C	776..973	CDD:279079	39/227 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910