DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9981 and ALA1

DIOPT Version :9

Sequence 1:	NP_001259610.1	Gene:	CG9981 / 32609	FlyBaseID:	FBgn0030746	Length:	1060	Species:	Drosophila melanogaster
Sequence 2:	NP_568146.1	Gene:	ALA1 / 830375	AraportID:	AT5G04930	Length:	1158	Species:	Arabidopsis thaliana

Alignment Length:	1100	Identity:	350/1100 - (31%)
Similarity:	548/1100 - (49%)	Gaps:	140/1100 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 NRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIVSFFVNETISPLV-----SLLPLLFVMIIT 87
            |.:.|.||:.|||||.|.:|||.|..|.|||:|.:    :|:.....|     |::||.||::::
plant    87 NSIKTAKYSVFTFLPRNLFEQFHRVAYIYFLVIAV----LNQLPQLAVFGRGASIMPLAFVLLVS 147

  Fly    88 ALKEGLEDYSRSKSDKLVNTARVTVIRNGKEEIINSQFIVPGDLVVVRNDGDVPCDLVLLQSSSA 152
            |:|:..||:.|.:||::.|.....|..:.:......:.|..|:::.|:::..:|||:|||.:|..
plant   148 AIKDAYEDFRRHRSDRVENNRLALVFEDHQFREKKWKHIRVGEVIKVQSNQTLPCDMVLLATSDP 212

  Fly   153 DRKCFVNTANLDGETNLKTICVPTNYLL-AGDHELQGKDCIVCEPSSADLYTFNGRLELRSGNDG 216
            ....:|.|.|||||:||||.......|| |.|.| .....|.||..:.::|.|...:|:    ||
plant   213 TGVVYVQTTNLDGESNLKTRYAKQETLLKAADME-SFNGFIKCEKPNRNIYGFQANMEI----DG 272

  Fly   217 AGSSAGDALPLTIDNLLLRGVRVKSTERVVGCAIYTGMHTKLQLNSRYTGNKSASSEKYINRFMV 281
            ...|.|.:      |::|||..:|:|...:|..:|.|..||..||:....:|.:..|..:|..::
plant   273 RRLSLGPS------NIILRGCELKNTAWALGVVVYAGGETKAMLNNSGAPSKRSRLETRMNLEII 331

  Fly   282 ALIVGMIVVVVV-----------------LYLIERHKEAKIVPTMPYQGPPTNFNS-----AWQI 324
            .|.:.:||:..:                 ..|..|.|:        |...|...|.     .|:|
plant   332 LLSLFLIVLCTIAAATAAVWLRTHRDDLDTILFYRRKD--------YSERPGGKNYKYYGWGWEI 388

  Fly   325 FEDFLSFLLLFNYMVPISAYMNIEVYRIFGMHFMHNDLHLYDEETDQPCRVNASNLNEELGQVNI 389
            |..|...::::..|:|||.|:::|:.||...:||.||..:|||.:|...:..|.|:||:|||:..
plant   389 FFTFFMAVIVYQIMIPISLYISMELVRIGQAYFMTNDDQMYDESSDSSFQCRALNINEDLGQIKY 453

  Fly   390 LFSDKTGTLTKNLMKFVNCYVPGTNYQLQNTHLVSEGTDEKFELEKLDADAAVL----------- 443
            ||||||||||.|.|:|....:.|.:|..:      |..|.:.....::.|..:|
plant   454 LFSDKTGTLTDNKMEFQCACIEGVDYSDR------EPADSEHPGYSIEVDGIILKPKMRVRVDPV 512

  Fly   444 --------------------FEALAVCHT-VEVLQEVGDKTLESSESVSEQSHLMSRNIVDRYQA 487
                                |.:||.|:| |.::....|..::               :|| ||.
plant   513 LLQLTKTGKATEEAKRANEFFLSLAACNTIVPIVSNTSDPNVK---------------LVD-YQG 561

  Fly   488 SSPDEKALLEGCASLG-LVYEGQENDVLSICRYPSAEKVQFKRLHVLEFSSERQRMSVIVRDQSD 551
            .||||:||:...|:.| |:.|.....::...|   .|..:|..|.:.||.|:|:|||||:.....
plant   562 ESPDEQALVYAAAAYGFLLIERTSGHIVINVR---GETQRFNVLGLHEFDSDRKRMSVILGCPDM 623

  Fly   552 TIWLYSKGAESAIFPRCKAS--PLVEQTDAQITKYAQNGLRTMAVGRRMLTDDELFHFEELYRKA 614
            ::.|:.|||:|::|.....|  .::.:|..|:..|:.:||||:.||.|.|.|.|...:...:..|
plant   624 SVKLFVKGADSSMFGVMDESYGGVIHETKIQLHAYSSDGLRTLVVGMRELNDSEFEQWHSSFEAA 688

  Fly   615 NTQLSNRNELIASCYETVENELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAYN 679
            :|.|..|..|:......:|..|.::||||:||.||..|.|.:|:|:.||:|:|||||||.|||.:
plant   689 STALIGRAGLLRKVAGNIETNLRIVGATAIEDKLQRGVPEAIESLRIAGIKVWVLTGDKQETAIS 753

  Fly   680 IGLACRHIPRGSKQHFIINTTEPAELLARLD-----MIGDDEPE--VLIVDGTTITALLEHTPRQ 737
            ||.:.|.:.|..:| .:||:.........|:     :..:||.:  .||:|||::..:|::....
plant   754 IGFSSRLLTRNMRQ-IVINSNSLDSCRRSLEEANASIASNDESDNVALIIDGTSLIYVLDNDLED 817

  Fly   738 -FADLALRCRAVLCCRLSPLQKSEIVTLIKRRKKYITAAIGDGANDVSMIQEAHIGIGITGREGK 801
             ...:|.:|.|:||||::|.||:.||.|:|.|...:|.|||||||||||||.|.:|:||:|:||:
plant   818 VLFQVACKCSAILCCRVAPFQKAGIVALVKNRTSDMTLAIGDGANDVSMIQMADVGVGISGQEGR 882

  Fly   802 QAARCADFSIARFEMLRRLFLVHGHYNSQRLAFLVLFYCYKN---IIITGCMALYQVYDLYSATN 863
            ||...:||::.:|..|..|.|||||:|.||:.:::|:..|:|   ::|.....|:..|.|.:|..
plant   883 QAVMASDFAMGQFRFLVPLLLVHGHWNYQRMGYMILYNFYRNAVFVLILFWYVLFTCYTLTTAIT 947

  Fly   864 VYNSIYLWLFDIVYISFSFTVLAICDKDYSEETLLSHPELYKPLAHNRQASMGVFSLWILNGFVQ 928
            .::|:   |:.::|.:....::.|.|||...:|||.||:||.........|..:|...:::...|
plant   948 EWSSV---LYSVIYTAIPTIIIGILDKDLGRQTLLDHPQLYGVGQRAEGYSTTLFWYTMIDTIWQ 1009

  Fly   929 CFIIFF---FTYAMLNDANVLFNGGQTASFQTFGTMLITIIVIVGNLKLLLVAHYMTYRNFAMIL 990
            ...|||   |.|           .|.|....:.|.:.....|:|.||.|.:......:...|.|.
plant  1010 SAAIFFIPMFAY-----------WGSTIDTSSLGDLWTIAAVVVVNLHLAMDVIRWNWITHAAIW 1063

  Fly   991 ASIAAFMLTTYLYNLYTSGELYDVYNQFLSSLPIWLFTIICSVACLLPDFVIKVVNDMYR 1050
            .||.|..:...:.::..:...|....|...:...|...:...|..|||.|.||.:.:.||
plant  1064 GSIVAACICVIVIDVIPTLPGYWAIFQVGKTWMFWFCLLAIVVTSLLPRFAIKFLVEYYR 1123

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9981	NP_001259610.1	PhoLip_ATPase_N	20..66	CDD:292826	19/37 (51%)
		ATPase-Plipid	28..1051	CDD:273734	349/1099 (32%)
		E1-E2_ATPase	84..>189	CDD:278548	35/105 (33%)
		Cation_ATPase	<489..568	CDD:289987	29/79 (37%)
		HAD_like	<758..807	CDD:304363	29/48 (60%)
		PhoLip_ATPase_C	804..1050	CDD:292829	66/251 (26%)
ALA1	NP_568146.1	PLN03190	1..1158	CDD:215623	349/1099 (32%)
		PhoLip_ATPase_N	70..133	CDD:292826	21/49 (43%)
		Cation_ATPase	539..638	CDD:289987	36/117 (31%)
		HAD_like	<854..885	CDD:304363	22/30 (73%)
		PhoLip_ATPase_C	885..1125	CDD:292829	67/252 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100089
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.720