DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9981 and AT3G27870

DIOPT Version :9

Sequence 1:	NP_001259610.1	Gene:	CG9981 / 32609	FlyBaseID:	FBgn0030746	Length:	1060	Species:	Drosophila melanogaster
Sequence 2:	NP_189425.2	Gene:	AT3G27870 / 822407	AraportID:	AT3G27870	Length:	1189	Species:	Arabidopsis thaliana

Alignment Length:	1142	Identity:	384/1142 - (33%)
Similarity:	567/1142 - (49%)	Gaps:	167/1142 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 NRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIVSFFVNETISPLVS------LLPLLFVMII 86
            |.|:|||||...|:|.:.:|||||....|||::..|||      |||..      |.|||.|:..
plant    58 NYVSTTKYTAANFIPKSLFEQFRRVANIYFLVVAFVSF------SPLAPYTAPSVLAPLLIVIGA 116

  Fly    87 TALKEGLEDYSRSKSDKLVNTARVTVIRNGKE-EIINSQF--IVPGDLVVVRNDGDVPCDLVLLQ 148
            |.:|||:||..|.|.|...|..:|.|:  ||. ..:.:::  :..||||.|..|...|.||:||.
plant   117 TMVKEGVEDLRRRKQDVEANNRKVEVL--GKTGTFVETKWKNLRVGDLVKVHKDEYFPADLLLLS 179

  Fly   149 SSSADRKCFVNTANLDGETNLKTICVPTNYLLAGDHE--LQGKDCIVCEPSSADLYTFNGRLELR 211
            ||..|..|:|.|.|||||||||   :.....:..|.|  ...:..|.||..:..||:|.|.|...
plant   180 SSYEDGICYVETMNLDGETNLK---LKHALEITSDEESIKNFRGMIKCEDPNEHLYSFVGTLYFE 241

  Fly   212 SGNDGAGSSAGDALPLTIDNLLLRGVRVKSTERVVGCAIYTGMHTKLQLNSRYTGNKSASSEKYI 276
                      |...||:...:|||..::|:|:.|.|..::||..||:..|:....:|.:..||.:
plant   242 ----------GKQYPLSPQQILLRDSKLKNTDYVYGVVVFTGHDTKVMQNATDPPSKRSKIEKKM 296

  Fly   277 NRFMVALIVGMIVVVV---VLYLIERHKEAK---------IVP--TMPYQGPPTNFNSAWQIFED 327
            ::.:..|...:||:..   |.:.|...::..         :.|  |..:..|.....:|   |..
plant   297 DQIIYILFSILIVIAFTGSVFFGIATRRDMSDNGKLRRWYLRPDHTTVFYDPRRAVAAA---FFH 358

  Fly   328 FLSFLLLFNYMVPISAYMNIEVYRIFGMHFMHNDLHLYDEETDQPCRVNASNLNEELGQVNILFS 392
            ||:.|:|:.|::|||.|::|||.::....|::.|..:|.||||:|.|...||||||||||:.:.|
plant   359 FLTALMLYGYLIPISLYVSIEVVKVLQSIFINQDQEMYHEETDRPARARTSNLNEELGQVDTILS 423

  Fly   393 DKTGTLTKNLMKFVNCYVPGTNY-----------QLQNTHLVSE--GTDEKFELEKLDA------ 438
            |||||||.|.|:||.|.:.||.|           :.|...:..|  |.:|...:::..|
plant   424 DKTGTLTCNSMEFVKCSIAGTAYGRGMTEVEVALRKQKGLMTQEEVGDNESLSIKEQKAVKGFNF 488

  Fly   439 -DAAVL----------------FEALAVCHTV--EVLQEVGDKTLESSESVSEQSHLMSRNIVDR 484
             |..::                |..||:|||.  :|..:.|:.|
plant   489 WDERIVDGQWINQPNAELIQKFFRVLAICHTAIPDVNSDTGEIT--------------------- 532

  Fly   485 YQASSPDEKALLEGCASLGLVYEGQENDVLSI--CRYPSAEKVQ--FKRLHVLEFSSERQRMSVI 545
            |:|.||||.|.:.....||..:..:....:|:  ..:.:.|||.  ::.||||||||.|:|||||
plant   533 YEAESPDEAAFVIASRELGFEFFSRSQTSISLHEIDHMTGEKVDRVYELLHVLEFSSSRKRMSVI 597

  Fly   546 VRDQSDTIWLYSKGAESAIFPR-CKASPLVE-QTDAQITKYAQNGLRTMAVGRRMLTDDELFHFE 608
            ||:..:.:.|.||||:|.:|.| .|.....| :|...|.|||:.||||:.:..|.:.:||...:|
plant   598 VRNPENRLLLLSKGADSVMFKRLAKHGRQNERETKEHIKKYAEAGLRTLVITYREIDEDEYIVWE 662

  Fly   609 ELYRKANTQLS-NRNELIASCYETVENELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGD 672
            |.:..|.|.:: :|:.||.:..:.:|.:|.|||:||:||.||:.|.:.:|.|..||:||||||||
plant   663 EEFLNAKTLVTEDRDALIDAAADKIEKDLILLGSTAVEDKLQKGVPDCIEKLSQAGVKIWVLTGD 727

  Fly   673 KVETAYNIGLACRHIPRGSKQHFIINTTEPAELLARLDMIGDDEPEV------------------ 719
            |.|||.|||.||..:..|.||  |:.|.:.:::.| |:..||.|...
plant   728 KTETAINIGYACSLLREGMKQ--ILVTLDSSDIEA-LEKQGDKEAVAKASFQSIKKQLREGMSQT 789

  Fly   720 ----------------LIVDGTTIT-ALLEHTPRQFADLALRCRAVLCCRLSPLQKSEIVTLIKR 767
                            |::||.::| ||.....::|.:||:||.:|:|||.||.||:.:..|:|.
plant   790 AAVTDNSAKENSEMFGLVIDGKSLTYALDSKLEKEFLELAIRCNSVICCRSSPKQKALVTRLVKN 854

  Fly   768 RKKYITAAIGDGANDVSMIQEAHIGIGITGREGKQAARCADFSIARFEMLRRLFLVHGHYNSQRL 832
            .....|.|||||||||.|:|||.||:||:|.||.||...:||:||:|..|.||.|||||:..:|:
plant   855 GTGRTTLAIGDGANDVGMLQEADIGVGISGAEGMQAVMASDFAIAQFRFLERLLLVHGHWCYRRI 919

  Fly   833 AFLVLFYCYKNIIITGCMALYQVYDLYSATNVYNSIYLWLFDIVYISFSFTVLAICDKDYSEETL 897
            ..::.::.|||:.....:..|:.|..:|....||..|:..:::.:.|.....|.:.|:|.|....
plant   920 TLMICYFFYKNLAFGFTLFWYEAYASFSGKPAYNDWYMSCYNVFFTSLPVIALGVFDQDVSARLC 984

  Fly   898 LSHPELYKPLAHNRQASMGVFSLWILNGFVQCFIIFFFTYAMLNDANVLF-NGGQTASFQTFGTM 961
            |.:|.||:....|...|......|:|||.:...||||.|...:  |...| ..||...:...|..
plant   985 LKYPLLYQEGVQNVLFSWERILGWMLNGVISSMIIFFLTINTM--ATQAFRKDGQVVDYSVLGVT 1047

  Fly   962 LITIIVIVGNLKLLLVAHYMTYRNFAMILASIAAFMLTTYLYNLYT---SGELYDVYNQFLSSLP 1023
            :.:.:|...|.::.:..:|.|:.....|..||..:.|...:|....   |...:.|:.:..:..|
plant  1048 MYSSVVWTVNCQMAISINYFTWIQHCFIWGSIGVWYLFLVIYGSLPPTFSTTAFQVFVETSAPSP 1112

  Fly  1024 I-WLFTIICSVACLLPDFVIKVVNDMYRKVPLKSKPV 1059
            | ||...:...:.|||.|.       ||...:|.:|:
plant  1113 IYWLVLFLVVFSALLPYFT-------YRAFQIKFRPM 1142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9981	NP_001259610.1	PhoLip_ATPase_N	20..66	CDD:292826	19/37 (51%)
		ATPase-Plipid	28..1051	CDD:273734	381/1132 (34%)
		E1-E2_ATPase	84..>189	CDD:278548	42/109 (39%)
		Cation_ATPase	<489..568	CDD:289987	35/83 (42%)
		HAD_like	<758..807	CDD:304363	26/48 (54%)
		PhoLip_ATPase_C	804..1050	CDD:292829	67/250 (27%)
AT3G27870	NP_189425.2	ATPase-Plipid	55..1149	CDD:273734	384/1142 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	104	1.000	Domainoid score	I2236
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100089
Panther	1	1.100	-	-	O	PTHR24092
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820