DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9981 and AT3G25610

DIOPT Version :9

Sequence 1:	NP_001259610.1	Gene:	CG9981 / 32609	FlyBaseID:	FBgn0030746	Length:	1060	Species:	Drosophila melanogaster
Sequence 2:	NP_189189.1	Gene:	AT3G25610 / 822148	AraportID:	AT3G25610	Length:	1202	Species:	Arabidopsis thaliana

Alignment Length:	1115	Identity:	389/1115 - (34%)
Similarity:	562/1115 - (50%)	Gaps:	136/1115 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 NRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIVSFFVNETISPLVSLLPLLFVMIITALKEG 92
            |.|.:||||..:|.|.:.:|||||...||||:..|:|.........:.:||||..|:..|.:|||
plant    60 NYVRSTKYTVASFFPKSLFEQFRRVANFYFLVTGILSLTDLSPYGAVSALLPLALVISATMVKEG 124

  Fly    93 LEDYSRSKSDKLVNTARVTV-IRNG---KEEIINSQFIVPGDLVVVRNDGDVPCDLVLLQSSSAD 153
            :||:.|.:.|..||..:|.| ..||   :||..|.:.   ||:|.|..|...|.||:||.||..|
plant   125 IEDWRRKQQDIEVNNRKVKVHDGNGIFRQEEWRNLRV---GDIVRVEKDEFFPADLLLLSSSYED 186

  Fly   154 RKCFVNTANLDGETNLKTI--CVPTNYLLAGDHELQG-KDCIVCEPSSADLYTFNGRLELRSGND 215
            ..|:|.|.|||||||||..  ...|:.||..|.:.:. :..:.||..:.:||.|.|.|.|..
plant   187 SVCYVETMNLDGETNLKVKQGLEATSSLLNQDSDFKDFRGVVRCEDPNVNLYVFVGTLALEE--- 248

  Fly   216 GAGSSAGDALPLTIDNLLLRGVRVKSTERVVGCAIYTGMHTKLQLNSRYTGNKSASSEKYINR-- 278
                   :..||:|..:|||..::::||.|.|..::||..||:..||....:|.:..|:.:::
plant   249 -------ERFPLSIQQILLRDSKLRNTEYVYGAVVFTGHDTKVIQNSTDPPSKRSRIERTMDKII 306

  Fly   279 -FMVALIVGMIVVVVVLYLIE-RHKEAKIVPTMPYQGPPTNFNSAWQIFED-----------FLS 330
             .|..|:..|..|..:::.:| |..:.|...|..:...|.:.:    ||.|           |.:
plant   307 YLMFGLVFLMSFVGSIIFGVETREDKVKNGRTERWYLKPDDAD----IFFDPERAPMAAIYHFFT 367

  Fly   331 FLLLFNYMVPISAYMNIEVYRIFGMHFMHNDLHLYDEETDQPCRVNASNLNEELGQVNILFSDKT 395
            ..:|::|.:|||.|::||:.::....|::.|:|:|.||||:|.:...||||||||.|:.:.||||
plant   368 ATMLYSYFIPISLYVSIEIVKVLQSIFINRDIHMYYEETDKPAQARTSNLNEELGMVDTILSDKT 432

  Fly   396 GTLTKNLMKFVNCYVPGTNY-------------QLQNTHLVSEGTDE------------KFELEK 435
            ||||.|.|:|:.|.:.|..|             :...:.||:|..|.            .||.|:
plant   433 GTLTCNSMEFIKCSIAGKAYGRGITEVERAMAVRSGGSPLVNEDLDVVVDQSGPKVKGFNFEDER 497

  Fly   436 L-------DADAAVL---FEALAVCHTVEVLQEVGDKTLESSESVSEQSHLMSRNIVDRYQASSP 490
            :       ..:||||   |..||||||..      .:|.|.|.:||             |:|.||
plant   498 VMNGNWVRQPEAAVLQKFFRLLAVCHTAI------PETDEESGNVS-------------YEAESP 543

  Fly   491 DEKALLEGCASLGLVYEGQENDVLSICRYP--SAEKVQ--FKRLHVLEFSSERQRMSVIVRDQSD 551
            ||.|.:......|..:..:..:.:|.....  |.|||:  ::.|:||||:|.|:||||||||...
plant   544 DEAAFVVAAREFGFEFFNRTQNGISFRELDLVSGEKVERVYRLLNVLEFNSTRKRMSVIVRDDDG 608

  Fly   552 TIWLYSKGAESAIFPRC--KASPLVEQTDAQITKYAQNGLRTMAVGRRMLTDDELFHFEELYRKA 614
            .:.|.||||::.:|.|.  .......:|...:.:||..||||:.:..|.:.::|...|.:.:.:|
plant   609 KLLLLSKGADNVMFERLAKNGRQFEAKTQEHVNQYADAGLRTLVLAYREVDENEYIEFNKSFNEA 673

  Fly   615 NTQLS-NRNELIASCYETVENELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAY 678
            ...:| :|..||....:.:|.:|.||||||:||.||..|.|.::.|..||:|||||||||:|||.
plant   674 KASVSEDREALIDEITDKMERDLILLGATAVEDKLQNGVPECIDKLAQAGIKIWVLTGDKMETAI 738

  Fly   679 NIGLACRHIPRGSKQHFIINTTEP-------------AELLARLDMI--------------GDDE 716
            |||.|...:.:..|| .|||...|             .||.:|..::              ...|
plant   739 NIGFASSLLRQEMKQ-IIINLETPQIKSLEKSGGKDEIELASRESVVMQLQEGKALLAASGASSE 802

  Fly   717 PEVLIVDGTTIT-ALLEHTPRQFADLALRCRAVLCCRLSPLQKSEIVTLIKRRKKYITAAIGDGA 780
            ...||:||.::| ||.:...:.|.|||..|.:|:|||.||.||:.:..|:|......|.||||||
plant   803 AFALIIDGKSLTYALEDEIKKMFLDLATSCASVICCRSSPKQKALVTRLVKSGTGKTTLAIGDGA 867

  Fly   781 NDVSMIQEAHIGIGITGREGKQAARCADFSIARFEMLRRLFLVHGHYNSQRLAFLVLFYCYKNII 845
            |||.|:|||.||:||:|.||.||...:|.:||:|..|.||.|||||:...|:|.::.::.||||.
plant   868 NDVGMLQEADIGVGISGVEGMQAVMSSDIAIAQFRYLERLLLVHGHWCYSRIASMICYFFYKNIT 932

  Fly   846 ITGCMALYQVYDLYSATNVYNSIYLWLFDIVYISFSFTVLAICDKDYSEETLLSHPELYKPLAHN 910
            ....:.||:.|..:|....||..:|.||::.:.|.....|.:.|:|.|.......|.||:....|
plant   933 FGVTVFLYEAYTSFSGQPAYNDWFLSLFNVFFSSLPVIALGVFDQDVSARFCYKFPLLYQEGVQN 997

  Fly   911 RQASMGVFSLWILNGFVQCFIIFFFTYAMLNDANVLFN-GGQTASFQTFGTMLITIIVIVGNLKL 974
            ...|......|:.|||:....|||.....|.  :.||: .|:||..:..|..:.|.:|.|.||::
plant   998 ILFSWKRIIGWMFNGFISALAIFFLCKESLK--HQLFDPDGKTAGREILGGTMYTCVVWVVNLQM 1060

  Fly   975 LLVAHYMTYRNFAMILASIAAFMLTTYLYNLYTSGELYDVYNQFLSSL----PIWLFTIICSVAC 1035
            .|...|.|:....:|..|||.:.:...:|...|.....|.|..||.:|    ..||.|:...:..
plant  1061 ALSISYFTWVQHIVIWGSIAFWYIFLMIYGAMTPSFSTDAYMVFLEALAPAPSYWLTTLFVMIFA 1125

  Fly  1036 LLPDFVIKVV 1045
            |:|.||.|.|
plant  1126 LIPYFVYKSV 1135

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9981	NP_001259610.1	PhoLip_ATPase_N	20..66	CDD:292826	19/37 (51%)
		ATPase-Plipid	28..1051	CDD:273734	389/1115 (35%)
		E1-E2_ATPase	84..>189	CDD:278548	46/111 (41%)
		Cation_ATPase	<489..568	CDD:289987	32/82 (39%)
		HAD_like	<758..807	CDD:304363	26/48 (54%)
		PhoLip_ATPase_C	804..1050	CDD:292829	79/247 (32%)
AT3G25610	NP_189189.1	PhoLip_ATPase_N	41..107	CDD:292826	19/46 (41%)
		ATPase-Plipid	57..1148	CDD:273734	389/1115 (35%)
		Cation_ATPase	521..624	CDD:289987	43/121 (36%)
		COG4087	<840..898	CDD:226572	30/57 (53%)
		PhoLip_ATPase_C	891..1141	CDD:292829	79/247 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100089
Panther	1	1.100	-	-	O	PTHR24092
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820