Protein Alignment CG9981 and Atp8a2

DIOPT Version :9

• Sequence 1: NP_001259610.1
• Gene: CG9981 / 32609
• FlyBaseID: FBgn0030746
• Length: 1060
• Species: Drosophila melanogaster
• Sequence 2: NP_056618.1
• Gene: Atp8a2 / 50769
• MGIID: 1354710
• Length: 1148
• Species: Mus musculus
• Alignment Length: 1095
• Identity: 375/1095 - (34%)
• Similarity: 568/1095 - (51%)
• Gaps: 130/1095 - (11%)

  Fly    28 NRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIVSFFVNETISP---LVSLLPLLFVMIITAL 89
            ||::|.||:..||||...|||.|||...:||.|.::....:  :||   ..:|:||:.::.|..:
Mouse    31 NRISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPD--VSPTGRYTTLVPLVIILTIAGI 93

  Fly    90 KEGLEDYSRSKSDKLVNTARVTVIRNGKEEIINSQFIVPGDLVVVRNDGDVPCDLVLLQSSSADR 154
            ||.:||:.|.|:|..||..:..|:|||....|..:.:..||:|.|.|...:|.|:||..||....
Mouse    94 KEIIEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVLNGQYLPADMVLFSSSEPQG 158

  Fly   155 KCFVNTANLDGETNLK-------TICVPTNYLLAGDHELQGKDCIVCEPSSADLYTFNGRLELRS 212
            .|:|.|||||||||||       |..:.|..:|.   :|.|:  |.||..:..||.|.|.|.|
Mouse   159 MCYVETANLDGETNLKIRQGLSHTTDMQTRDVLM---KLSGR--IECEGPNRHLYDFTGNLHL-- 216

  Fly   213 GNDGAGSSAGDALPLTIDNLLLRGVRVKSTERVVGCAIYTGMHTKLQLNSRYTGNKSASSEKYIN 277
              ||..|.|     |..|.:||||.::::|:.|.|..:|||..:||..||.....|.::.||..|
Mouse   217 --DGKSSVA-----LGPDQILLRGTQLRNTQWVFGVVVYTGHDSKLMQNSTKAPLKRSNVEKVTN 274

  Fly   278 RFMVALIVGMIVVVVVLYLIERHKEAKIVPTMPYQGPPTNFNSAWQIFE----------DFLSFL 332
             ..:.::.|:::|:.::         ..|..:.:.|  ::...:|.|.:          :.|:|:
Mouse   275 -VQILVLFGILLVMALV---------SSVGALFWNG--SHGGKSWYIKKMDTNSDNFGYNLLTFI 327

  Fly   333 LLFNYMVPISAYMNIEVYRIFGMHFMHNDLHLYDEETDQPCRVNASNLNEELGQVNILFSDKTGT 397
            :|:|.::|||..:.:||.:.....|::.|:.:|..|.|.|.....||||||||||..||||||||
Mouse   328 ILYNNLIPISLLVTLEVVKYTQALFINWDMDMYYIENDTPAMARTSNLNEELGQVKYLFSDKTGT 392

  Fly   398 LTKNLMKFVNCYVPGTNYQLQNTHLVSEGTDEKF--------------------ELEKLDADAAV 442
            ||.|:|.|..|.:.|..|. ....|..|.:.:.|                    .:|.....|..
Mouse   393 LTCNIMNFKKCSIAGVTYG-HFPELAREQSSDDFCRMTSCTNDSCDFNDPRLLKNIEDQHPTAPC 456

  Fly   443 LFE---ALAVCHTVEVLQEVGDKTLESSESVSEQSHLMSRNIVDRYQASSPDEKALLEGCASLGL 504
            :.|   .||||||| |.::.||:.:                    ||||||||.||::|...||.
Mouse   457 IQEFLTLLAVCHTV-VPEKDGDEII--------------------YQASSPDEAALVKGAKKLGF 500

  Fly   505 VYEGQENDVLSICRYPSAEKVQFKRLHVLEFSSERQRMSVIVRDQSDTIWLYSKGAESAIFPR-C 568
            |:.|:  ...|:......::..|..|:||||||:|:|||||||..|..:.||.|||::.||.| .
Mouse   501 VFTGR--TPYSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRLPSGQLRLYCKGADNVIFERLS 563

  Fly   569 KASPLVEQTDAQITKYAQNGLRTMAVGRRMLTDDELFHFEELYRKANTQLSNRNELIASCYETVE 633
            |.|..:|:|...:..:|..||||:.|....|:::|...:.::|::|:..|.:|.:.:..|||.:|
Mouse   564 KDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASIILKDRAQRLEECYEIIE 628

  Fly   634 NELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAYNIGLACRHIPRGSKQHFIIN 698
            ..|.||||||:||.||..|.||:..|..|.:|||||||||.|||.|||.:||.:   |:...:|.
Mouse   629 KNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLV---SQNMALIL 690

  Fly   699 TTEPAELLARL----------DMIGDDEPEVLIVDGTTIT-ALLEHTPRQFADLALRCRAVLCCR 752
            ..|.:....|.          :::|.:....||:||.|:. ||.....|.|.||||.|:||:|||
Mouse   691 LKEDSLDATRAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCR 755

  Fly   753 LSPLQKSEIVTLIKRRKKYITAAIGDGANDVSMIQEAHIGIGITGREGKQAARCADFSIARFEML 817
            :|||||||||.::|:|.|.||.|||||||||.|||.||:|:||:|.||.||...:|::||:|..|
Mouse   756 VSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSYL 820

  Fly   818 RRLFLVHGHYNSQRLAFLVLFYCYKNIIITGCMALYQVYDLYSATNVYNSIYL---W---LFDIV 876
            .:|.||||.::..|:...:|:..|||::      ||.:...::..|.::...|   |   |::::
Mouse   821 EKLLLVHGAWSYNRVTKCILYCFYKNVV------LYIIELWFAFVNGFSGQILFERWCIGLYNVI 879

  Fly   877 YISFSFTVLAICDKDYSEETLLSHPELYKPLAHNRQASMGVFSLWILNGFVQCFIIFFFTY-AML 940
            :.:.....|.|.::..::|::|..|:||:...:....:..||....:|..|...|:|:... |:.
Mouse   880 FTALPPFTLGIFERSCTQESMLRFPQLYRITQNAEGFNTKVFWGHCINALVHSLILFWVPMKALE 944

  Fly   941 NDANVLFNGGQTASFQTFGTMLITIIVIVGNLKLLLVAHYMTYRNFAMILASIAAFMLTTYLYN- 1004
            :|..|  ..|....:...|.::.|.:|:...||..|.....|..:...:..|:..:::...:|:
Mouse   945 HDTPV--TSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLIWLVFFGVYST 1007

  Fly  1005 ----LYTSGELYDVYNQFLSSLPIWLFTIICSVACLLPDFVIKVVNDMYRKVPLK 1055
                :..:.::.......|||...||...:...|||:.|...:......:|..|:
Mouse  1008 IWPTIPIAPDMKGQATMVLSSAYFWLGLFLVPTACLIEDVAWRAAKHTCKKTLLE 1062

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9981	NP_001259610.1	PhoLip_ATPase_N	20..66	CDD:292826	18/37 (49%)
		ATPase-Plipid	28..1051	CDD:273734	373/1089 (34%)
		E1-E2_ATPase	84..>189	CDD:278548	43/111 (39%)
		Cation_ATPase	<489..568	CDD:289987	37/79 (47%)
		HAD_like	<758..807	CDD:304363	32/48 (67%)
		PhoLip_ATPase_C	804..1050	CDD:292829	56/257 (22%)
Atp8a2	NP_056618.1	PhoLip_ATPase_N	17..79	CDD:292826	20/49 (41%)
		ATPase-Plipid	28..1066	CDD:273734	375/1095 (34%)
		E1-E2_ATPase	85..>170	CDD:278548	33/84 (39%)
		Cation_ATPase	466..564	CDD:289987	49/120 (41%)
		HAD_like	<776..805	CDD:304363	21/28 (75%)
		PhoLip_ATPase_C	808..1059	CDD:292829	56/258 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I7147
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820