DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9981 and SPAC4F10.16c

DIOPT Version :9

Sequence 1:	NP_001259610.1	Gene:	CG9981 / 32609	FlyBaseID:	FBgn0030746	Length:	1060	Species:	Drosophila melanogaster
Sequence 2:	NP_594759.1	Gene:	SPAC4F10.16c / 2543523	PomBaseID:	SPAC4F10.16c	Length:	1367	Species:	Schizosaccharomyces pombe

Alignment Length:	1243	Identity:	343/1243 - (27%)
Similarity:	562/1243 - (45%)	Gaps:	300/1243 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PLNRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITI---VSFFVNETISPLVSLLPLLFVMIIT 87
            |.|::.|||||..:|:|.|.:.||:.....:||.:|:   :..|..|.:.  :|.:||..:::.|
pombe   129 PSNKIRTTKYTPVSFIPKNLWNQFKNIANAFFLFVTLLQCIPLFCPEHLG--LSFIPLSVILLTT 191

  Fly    88 ALKEGLEDYSRSKSDKLVNT--------------------------------------------- 107
            |:|:|:|||.|...||..|.
pombe   192 AIKDGIEDYRRCVLDKKFNNTLTWKLVGFNNANALGEHIGLWRKLKKFISHTVADMSYCLKNSGI 256

  Fly   108 ----ARVTV------------------------------------------------IRNGKEEI 120
                |.:||                                                ..|.|.|.
pombe   257 SSGLATLTVDNISHRHSLESDSAFTLSSVSQDSLEIHEIGNSGPSNSFSVIQEQSTGSSNAKFER 321

  Fly   121 INSQFIVPGDLVVVRNDGDVPCDLVLLQSSSADRKCFVNTANLDGETNLK-------TICVPTNY 178
            :..:.::.||:|.|..|..:|.||::|.:.:::..|:|.|.|||||||||       |.|..:.|
pombe   322 VCRKSLLVGDIVKVLADEAIPADLLILSTENSNGVCYVETKNLDGETNLKDKYALCSTKCCKSEY 386

  Fly   179 LLAGDHELQGKDCIVCEPSSADLYTFNGRLELRSGNDGAGSSAGDAL--------PLTIDNLLLR 235
            ..:.     ....:.||...||||:.||.::.    .||..|..::.        |.:|.|:||.
pombe   387 RCSA-----ASFWVECEQPHADLYSLNGVVKA----PGAVQSPSESTNGRKIHEEPFSISNVLLC 442

  Fly   236 GVRVKSTERVVGCAIYTGMHTKLQLNSRYTGNKSASSEKYINRFMV---ALIVGMIVVVVVLYLI 297
            |..:::::.|:|..:|||..|::|.|...|.:|.:...:.:|..::   .|:..|.:...||..|
pombe   443 GCTLRNSKWVIGLVLYTGSETRIQKNRGLTPSKRSRITRDLNWTIILNFLLLFAMCLFSGVLRSI 507

  Fly   298 --ERHKEAKIVP------TMPYQGPPTNFNSAWQIFEDFLSFLLLFNYMVPISAYMNIEVYRIFG 354
              .::..|::..      |.|..|..:.|.|           |:||..:||||.|:.:::.|...
pombe   508 YSAQNNSARVFELSKNSNTAPAHGIISIFTS-----------LILFQNLVPISLYITMDIVRSIQ 561

  Fly   355 MHFMHNDLHLYDEETDQPCRVNASNLNEELGQVNILFSDKTGTLTKNLMKFVNCYVPGTNY---- 415
            .:|:.:|..:|||:.|.||...:.|::::|||:..:|||||||||:|:|.|..|.:.|..|
pombe   562 SYFIFSDREMYDEKLDCPCSPKSWNISDDLGQIEYIFSDKTGTLTQNIMSFKKCSINGIRYGKSH 626

  Fly   416 -------QLQNTHLVSEGTDEKFELEK-----------------------------------LDA 438
                   :.:|.: .:|....|.:|:|                                   :..
pombe   627 NEDTCIKKRRNLN-YNENLSCKVDLDKKKMLETLSLSDSPNPESITFISSKFVDHLQSNENYIQT 690

  Fly   439 DAAV-LFEALAVCHTVEVLQEVGDKTLESSESVSEQSHLMSRNIVDRYQASSPDEKALLEGCASL 502
            :|.. .|:|||:||:  |:.:|.|:||                   .|.|.||||:||::.....
pombe   691 EACFEFFKALALCHS--VVTDVQDETL-------------------IYNAQSPDEEALVKVARDF 734

  Fly   503 GLVYEGQENDVLSICRYP---SAEKVQFKRLHVLEFSSERQRMSVIVRDQSDTIWLYSKGAESAI 564
            |......:|.     ||.   ..|...|:.|.::.|:|.|:|||||:||:...|.|..|||::.|
pombe   735 GFTLLNTKNR-----RYTIRIRGENKNFRVLDIIPFTSTRKRMSVIIRDEDGIIHLICKGADTVI 794

  Fly   565 FPRCKA--SPLVEQTDAQITKYAQNGLRTMAVGRRMLTDDELFHFEELYRKANTQLSNRNELIAS 627
            |||..:  :.::|:|...:..::..|.||:.:.||.:...:...::..:.:||:.:..|||.::.
pombe   795 FPRLSSGQNNIIEKTKKHLASFSSEGFRTLCIARRTIDKQDYLEWKVNFNEANSAIHERNEKVSK 859

  Fly   628 CYETVENELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAYNIGLACRHIPRGSK 692
            ..|.:|.||:|||.||:||.|||:|.||:..|..||:|:|||||||||||.|||.:|
pombe   860 VSEMIEQELELLGGTAIEDKLQENVPETIALLAIAGIKLWVLTGDKVETAINIGYSC-------- 916

  Fly   693 QHFIINTTEPAELLARLD-----------------------MIGDDE--------------PEVL 720
                 |..:|...:.|:|                       .:|.||              ...:
pombe   917 -----NLLDPNMTIFRIDANSFGALEEVEAFIRNTLCFNFGYMGTDEEFRFLLKDHSPPSPKHAI 976

  Fly   721 IVDGTTITALL-EHTPRQFADLALRCRAVLCCRLSPLQKSEIVTLIKRRKKYITAAIGDGANDVS 784
            ::||..:..:| |.....|..|..:|:.|||||:||.||:.:|.|:|:....:|.||||||||||
pombe   977 VIDGDALNFVLSEQVSFLFLMLCKQCKTVLCCRVSPSQKAAVVALVKKSLNVVTLAIGDGANDVS 1041

  Fly   785 MIQEAHIGIGITGREGKQAARCADFSIARFEMLRRLFLVHGHYNSQRLAFLVLFYCYKNIIITGC 849
            |||||.:|:||.|.||:.|:..||::|.:|..|.||.||||.::.:|::.::.|:.|||:|.|..
pombe  1042 MIQEADVGVGIKGVEGQAASMSADYAIGQFSFLGRLLLVHGRWDYKRMSQMISFFFYKNVIWTFI 1106

  Fly   850 MALYQVYDLYSATNVYNSIYLWLFDIVYISFSFTVLAICDKDYSEETLLSHPELYKPLAHNRQAS 914
            :..||.|:.:....:::..|:.||::::.|....:....|:|......:.:|.||      ::..
pombe  1107 LFWYQFYNEFDGNYIFDYTYVMLFNLLFTSLPVIIAGCFDQDVDASVSMKNPSLY------QRGI 1165

  Fly   915 MGV------FSLWILNGFVQ---CFIIFFFTYAMLNDANVLFNGGQTASFQTFGTMLITIIVIVG 970
            :|:      |..::|:|..|   ||.:..|.: ...|. |.:.|......:..|..:.:..:.|.
pombe  1166 LGLEWNGKRFWSYMLDGIYQSLVCFGVALFVF-KFGDF-VSWTGRNIECIEDIGLFISSPTIFVI 1228

  Fly   971 NLKLLLVAHYMTYRNFAMILASIAAFMLTTYLYNLYTSGELYDVY---NQFLSSLPIWLFTIICS 1032
            |:.:|:....:...:....:.||..|.:.|::|:  ..|..|..:   ::...:...|..|::..
pombe  1229 NIFILMNQERLNLISLITWMFSIGVFWIWTFIYS--EVGPSYAFHKSASRTCQTFGFWCVTVLTI 1291

  Fly  1033 VACLLPDF 1040
            ..||||.|
pombe  1292 ALCLLPRF 1299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9981	NP_001259610.1	PhoLip_ATPase_N	20..66	CDD:292826	15/42 (36%)
		ATPase-Plipid	28..1051	CDD:273734	342/1241 (28%)
		E1-E2_ATPase	84..>189	CDD:278548	41/208 (20%)
		Cation_ATPase	<489..568	CDD:289987	31/81 (38%)
		HAD_like	<758..807	CDD:304363	27/48 (56%)
		PhoLip_ATPase_C	804..1050	CDD:292829	59/249 (24%)
SPAC4F10.16c	NP_594759.1	ATPase-Plipid	128..1318	CDD:273734	343/1243 (28%)
		PhoLip_ATPase_N	<128..174	CDD:292826	16/44 (36%)
		Cation_ATPase	702..800	CDD:289987	41/123 (33%)
		R3H	854..913	CDD:294210	35/58 (60%)
		HAD_like	<1013..1050	CDD:304363	21/36 (58%)
		PhoLip_ATPase_C	1061..1310	CDD:292829	59/249 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100089
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710