DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9981 and catp-3

DIOPT Version :9

Sequence 1:NP_001259610.1 Gene:CG9981 / 32609 FlyBaseID:FBgn0030746 Length:1060 Species:Drosophila melanogaster
Sequence 2:NP_505083.1 Gene:catp-3 / 179189 WormBaseID:WBGene00015660 Length:1054 Species:Caenorhabditis elegans


Alignment Length:1166 Identity:231/1166 - (19%)
Similarity:411/1166 - (35%) Gaps:369/1166 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 FYEQFRRAVYFYFLIITIVSF--FVNETISPL-----VSLLPLLFVMIITAL---KEGLEDYSRS 99
            |..||:..::........:.|  ::.:....|     :.::.::|:|.:.:.   |:|:|.....
 Worm    96 FVRQFKNLLWVLMFGAAALCFLTYIYDPTDALNLYVGIFIVAIVFIMCVVSFFEEKKGVEVVRAF 160

  Fly   100 KSDKLVNTARVTVIRNGKEEIINSQFIVPGDLVVVRNDGDVPCDLVLLQSSSADRKCFVNTANLD 164
            ::  |:.|: ..|||:|||.::|.:.:|.||:||||:...||.|:.::    |....|:.|:::.
 Worm   161 QT--LMPTS-CQVIRDGKEILLNPEELVVGDVVVVRSGCKVPADMRII----ACTDFFLETSSIT 218

  Fly   165 GET-----NLKTICVPTNYLLAGDHELQGKDCIVCEPSSADLYTFNGRLELRSGNDGAGSSAGDA 224
            ||.     :.||....|:...:.:....|..|:                      ||.|      
 Worm   219 GEAEPLEFHSKTADAKTSIFESYNIAFNGSFCV----------------------DGEG------ 255

  Fly   225 LPLTIDNLLLRGVRVKSTERVVGCAIYTGMHTKLQLNSRYTGNKSASSEKYINRFMVALIVGMIV 289
                      .|:.:::.|..|     .|....|.|..:   :|....|..|.||:..:.|..|.
 Worm   256 ----------YGIIIRTGENTV-----IGQIASLTLGQK---DKKCKFETEIERFVQFITVMAIT 302

  Fly   290 VVVVLYLIERHKEAKIVPTMPYQGPPTN-FNSAWQIFEDFLSFLLLFNYMVP------ISAYMNI 347
            :..|::.|               |...| .|...::|  ...||::....||      ::..:.|
 Worm   303 MATVIFTI---------------GLLVNGGNDVIRLF--VTGFLMVIIANVPQGLPTTVTTELTI 350

  Fly   348 EVYRIFGMHFMHNDLHLYDEETDQPCRVNASNLNEELGQVNILFSDKTGTLTKNLMKFVNCYVPG 412
            ...|:...:.....|...|                .:|...::.||||||||||.|...:.:.  
 Worm   351 IARRMAKKNVFLKKLEKID----------------SVGATTLIASDKTGTLTKNCMTVTDLWY-- 397

  Fly   413 TNYQLQNTHLVSEG-TDEKFELEKL------DADAAVLFEALAVCHTVEVLQEVG---------- 460
             |....:....::| |.:|..|..:      ||....:...:.||:...:...:.          
 Worm   398 -NNSYNSARPENQGRTTKKRNLNAINTIGWYDAPLKDILSVICVCNKARIENNLTTKVRPPRVDS 461

  Fly   461 --DKTLESSESVSEQSHLMSRNIVDRYQASSPDEKALLEGCA----------SLGLVYEGQENDV 513
              |.|:..|:.|.|.  |:|.|         |.|.|||...:          |..:|:|...|.|
 Worm   462 ELDLTVYKSQPVKEM--LISGN---------PSEVALLRYASGMLDAMEVRDSFHVVFEVPFNSV 515

  Fly   514 LSICRYPSAEKVQFKRLHVLEFSSE--------RQRMSVIVRDQSDTIWLYSKGAESAIFPRCKA 570
                          ::.|::..::|        :::::..|.     ..|..|||...:...|..
 Worm   516 --------------RKYHLILATTEATWAEIDDKKKVNADVE-----FILMIKGAPDVLIKSCST 561

  Fly   571 SPLVEQTDAQITKYAQNGLRTMAVGRRMLTDDELFHFEELYR-------------------KANT 616
            ..:             :|:.....|:||  ||    |.|.|.                   .|.:
 Worm   562 INI-------------DGVPMELNGKRM--DD----FNEAYETFGDEGCRVIGFACKKFRAPATS 607

  Fly   617 QLSNRNELIASCYETVENELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAYNIG 681
            ..|.::..|..      :..|.||.:|:.|..::.....::|.:.||:|::::|||...||..| 
 Worm   608 TFSIKSNTIPM------DNWDFLGMSAIMDPPRDDTPRAIKACKEAGIKVYMVTGDHKSTATAI- 665

  Fly   682 LACRHIPRGSKQHFIINTTEPAELLARLDMIGDDEPEVL---------IVDGTTITALLEHTPRQ 737
                     ::|..:|:|.|...|        |...:|:         ::.|..:..|.|   :|
 Worm   666 ---------ARQIGMIDTEEVTNL--------DHNRQVIRRTNSQDWAVITGPELPGLSE---KQ 710

  Fly   738 FADLALRCRAVLCCRLSPLQKSEIVTLIKRRKKYITAAIGDGANDVSMIQEAHIGI--GITGRE- 799
            : |..|..|.::..|.:|..|..|||..::|.:.:|.. |||.||...:::|.:|:  |:.|.: 
 Worm   711 W-DALLEHRYIVFARTTPEHKLMIVTESQKRGECVTVT-GDGVNDAPALKKADVGVAMGLAGSDV 773

  Fly   800 GKQAARCADFSIARFEMLRRLFLVHGHYNSQRLAFLVLFYCYKNIIITGCMALYQVYDLYSATNV 864
            .||||              .:.|:..:::|               |:.|......::|....|..
 Worm   774 AKQAA--------------DIILLDDNFSS---------------IVAGIEEGRLLFDNLRKTIA 809

  Fly   865 YNSIYLWLFDIVYISFSF--------TVLAICDKDY-------------------------SEET 896
            |...::|. ::|.:..:|        |.:.|...|.                         ..||
 Worm   810 YTMTHMWP-ELVPVMLNFFFGFPLGLTPVQILSIDLITDIPPAVSLAYEGPEADIMLQPPRKRET 873

  Fly   897 ------LLSHPELYKPLAHNRQASMGVFSLWILNGFVQCFIIF------------FFTY--AMLN 941
                  |:::..|:..:..:....:.....:.|||.....:.|            |.||  .:||
 Worm   874 HLVTKGLITYTYLFMSIFISVGGVVAYLLSYYLNGIYPSELAFSSNDHFKVGASNFTTYNGVVLN 938

  Fly   942 DANVLFNGGQTASFQTFGTMLITIIVIVGNL---------KLLLVAHYMTYRNFAMILASIAAFM 997
            ....:|...|.|:       ...|.|:||..         ::.:..|.|.  |...|||.|...:
 Worm   939 AEQQVFMAAQAAA-------AFHIAVVVGQAWHLWMCLTRRVSIFVHGMA--NIVAILAVIIDLL 994

  Fly   998 LTTYLYNLYTSGELYDVYNQFLSSLPIWLFTIICSVACLLPDFVIKVVNDMYRKVPLKSKP 1058
            |....  .:..|..|    .|.|..|.|    .|.:..::....|.:.|:: ||..:::.|
 Worm   995 LICLF--TFVPGVQY----VFGSQPPPW----ECWLVPVIVGIWIWIFNEL-RKFGIRNYP 1044

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9981NP_001259610.1 PhoLip_ATPase_N 20..66 CDD:292826 4/22 (18%)
ATPase-Plipid 28..1051 CDD:273734 228/1157 (20%)
E1-E2_ATPase 84..>189 CDD:278548 31/112 (28%)
Cation_ATPase <489..568 CDD:289987 17/96 (18%)
HAD_like <758..807 CDD:304363 19/51 (37%)
PhoLip_ATPase_C 804..1050 CDD:292829 51/307 (17%)
catp-3NP_505083.1 HAD_like 66..1044 CDD:389748 230/1164 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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