DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9981 and catp-4

DIOPT Version :9

Sequence 1:	NP_001259610.1	Gene:	CG9981 / 32609	FlyBaseID:	FBgn0030746	Length:	1060	Species:	Drosophila melanogaster
Sequence 2:	NP_497034.2	Gene:	catp-4 / 175120	WormBaseID:	WBGene00007248	Length:	1015	Species:	Caenorhabditis elegans

Alignment Length:	997	Identity:	210/997 - (21%)
Similarity:	356/997 - (35%)	Gaps:	299/997 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 LPLLFVMIITALKEGLED-YSRSKSDKLVNT------ARVTVIRNGKEEIINSQFIVPGDLVVVR 135
            :.::...::|.  .||.| |...||..|:::      .:..|:|:|....|..:.:|.||||..|
Worm   116 MAIILATVVTV--TGLFDFYQNRKSGNLMDSFANMIPPKTLVVRDGATREIEVKDLVVGDLVRFR 178

  Fly   136 NDGDVPCDLVLLQSSSADRKCFVNTANLDGETNLKTICVPTNYLLAGDHELQGKDCIVCEPSSAD 200
            ....||.||.:    :..|...|:.::|.||:..:|    .|......:.|:.|:  :|..|::.
Worm   179 GGDRVPADLRV----TLARGLKVDNSSLTGESEPQT----RNMNCTSKNALETKN--LCMFSTSV 233

  Fly   201 LYTFNGRLELRSGNDGAGSSAGDALPLTIDNLLLRGVRVKSTERVVGCAIYTGMHTKLQLNSRYT 265
            |             :|:|.                           |..|.||..|       :.
Worm   234 L-------------EGSGE---------------------------GIIIGTGDRT-------FV 251

  Fly   266 GNKSASS----------EKYINRF-----MVALIVGMIVVVVVLYLIERHKEAKIVPTMPYQGPP 315
            |..:|.:          .|.||.|     :||..||:...::.|.               |:.||
Worm   252 GRIAALTTQVDPGPTPLAKEINHFIKIISIVAFTVGIAFFILALV---------------YEYPP 301

  Fly   316 TNFNSAWQIFEDFLSFLLLFNYMVPISAYMNIEVYRIFGMHFMHNDLHLYDEETDQPCRVNASNL 380
                     .:..:.|:.:....||......:.|........|....          |.|.....
Worm   302 ---------LKAIVFFMGIVVANVPEGIVPTVTVSLTLTAVKMRKKF----------CLVKKLQA 347

  Fly   381 NEELGQVNILFSDKTGTLTKNLMKFVNCYVPG----TNYQLQNTHLVSEGTDEKFELEKLDADAA 441
            .|.||..:.:.||||||||:|.|...:.:..|    |.....|.|...|   :|:|.|    |:
Worm   348 VETLGSTSTICSDKTGTLTQNRMTVTHLWFDGKIKDTEILPPNDHFKGE---KKYEKE----DS- 404

  Fly   442 VLFEALAVCHTVEVLQEVGDKTLESSESVSEQSHLMSRNIVDRYQASSPDEKALLEGCASL-GLV 505
              ::.|..|.|:         ...|...|.|....:::.:|:    ....|.|::..|..: |
Worm   405 --YQKLLRCATL---------CSRSHFRVPEFDVPLAKRVVN----GDASEVAIMRYCEMIRG-- 452

  Fly   506 YEGQENDVLSICRYPSAEKVQFKRLHVLEFSSERQRMSVIVRDQSDTIWLYSKGAESAIFPRCKA 570
             :||.::...|  .|...::.|.       |:.:.::|:....:...| |..|||...|...|
Worm   453 -DGQVDEFRKI--MPKIGEIPFN-------STNKYQLSIHPMSKKQNI-LVMKGAPEKILKLC-- 504

  Fly   571 SPLVEQTDAQITKYAQNGLRTMAVGRRMLTDDELFHFEELYRKANTQLSNRNELIASCYE----- 630
                       :.|.||| .|..|.::         ||:.:::|...|.:..|.:....:
Worm   505 -----------STYYQNG-ETKNVSKK---------FEKEFQQAYETLGSYGERVLGFCDLEMST 548

  Fly   631 ----------------TVENELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAYN 679
                            .::| |..||..::.|..:..|.|.:...|.||:::.::|||...||..
Worm   549 TKFPPGFKFNMEEPNFPIKN-LRFLGLISMIDPPRPGVPEAVRVCQNAGIRVVMVTGDHPITARA 612

  Fly   680 IGLACRHIPRGSKQHFI---INTTEPAELLARLDMIGDD-------EPE-VLIVDGTTITALLEH 733
            |         .::.|.|   :..||......:.|...|:       :|. .:::.|..:|.:
Worm   613 I---------ANQVHIIEENVQVTEIVNADPKCDPASDEIYGKGRLKPTGAVVIHGEQLTTM--- 665

  Fly   734 TPRQFADLALRCRAVLCCRLSPLQKSEIVTLIKRRKKYITAAIGDGANDVSMIQEAHIGI--GIT 796
            :|:....:......::..|.||.||.:||...:.... |....|||.||...:::|.|||  |||
Worm   666 SPKTLKAVVTNYHQIVFARTSPAQKLQIVEAFQSVGN-IVGVTGDGVNDAPALRKADIGIAMGIT 729

  Fly   797 GRE-GKQAARCADFSIARFEMLRRLFLVHGHYNS-------QRLAF-----LVLFYCYKNI-IIT 847
            |.: .||||              .:.|::.::.|       .||.|     .:.:....|| .||
Worm   730 GTDVSKQAA--------------DMILLNDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEIT 780

  Fly   848 GCMALYQVYDLYSATNVYNSIYLWLFDI-----VYISFSFTVLAICDKDYSEETLLSHP---ELY 904
            ..|:    |.|:......:.|.:.:.|:     ..|||::.|        .|..::...   .||
Worm   781 PFMS----YVLFGLPLPMSIIAILMIDLGTDLWPAISFAYEV--------PESDIMQRAPRNPLY 833

  Fly   905 KPLAHNRQ---ASMGVFSLWILNGFVQCFIIF----FFTYAMLNDANVLFNG---------GQTA 953
            ..|.:.|.   :.|.:.::....||...|::.    :|...:||.:....|.         ||..
Worm   834 DKLVNKRLVMFSYMQIGAIQACAGFTTYFVLMMSNGWFPQDLLNISEQWDNKYIDDLEDSYGQQW 898

  Fly   954 SFQT--------FGTMLITIIV 967
            |:::        :||...||:|
Worm   899 SYESRKALESCCYGTFFFTIVV 920

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9981	NP_001259610.1	PhoLip_ATPase_N	20..66	CDD:292826
		ATPase-Plipid	28..1051	CDD:273734	210/997 (21%)
		E1-E2_ATPase	84..>189	CDD:278548	30/111 (27%)
		Cation_ATPase	<489..568	CDD:289987	17/79 (22%)
		HAD_like	<758..807	CDD:304363	21/51 (41%)
		PhoLip_ATPase_C	804..1050	CDD:292829	40/209 (19%)
catp-4	NP_497034.2	ATPase-IIC_X-K	9..1015	CDD:273445	210/997 (21%)
		Cation_ATPase_N	24..95	CDD:214842
		E1-E2_ATPase	118..349	CDD:278548	62/323 (19%)
		Cation_ATPase	414..507	CDD:289987	22/131 (17%)
		HAD	<582..718	CDD:289480	34/148 (23%)
		Cation_ATPase_C	791..1000	CDD:279079	27/138 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910