DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9981 and atp9a

DIOPT Version :9

Sequence 1:	NP_001259610.1	Gene:	CG9981 / 32609	FlyBaseID:	FBgn0030746	Length:	1060	Species:	Drosophila melanogaster
Sequence 2:	XP_005174184.3	Gene:	atp9a / 101886226	-ID:	-	Length:	1046	Species:	Danio rerio

Alignment Length:	1067	Identity:	328/1067 - (30%)
Similarity:	537/1067 - (50%)	Gaps:	108/1067 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PLRIQIGGIESRQQK-PLNRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIVSFFVNE-TISP 73
            |..:.:|..|.|:|: |.|.:...||.:|||||...:.||:.....|||::. .|.|||| .:..
Zfish    38 PRTVWLGHPEKREQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLA-CSQFVNELRLGA 101

  Fly    74 LVSL-LPLLFVMIITALKEGLEDYSRSKSDKLVNTARVTVIRNGKEEIINSQFIVPGDLVVVRND 137
            |.:. :||.||:|||.::|.:|:......||.||:...:.:.......:.|..|..|||::|..:
Zfish   102 LYTYWVPLGFVLIITIVREAVEEVRCFLRDKEVNSQIYSKLSTRGTVKVKSSGIQVGDLIIVEKN 166

  Fly   138 GDVPCDLVLLQSSSADRKCFVNTANLDGETNLK-------TICVPTNYLLAGDHELQGKDCIVCE 195
            ..||.|::.|::|..:..||:.|..|||||:.|       |..:||    |.| .||.:..:..|
Zfish   167 QRVPADMIFLRTSERNGSCFLRTDQLDGETDWKLRLPVACTQRLPT----AAD-LLQIRSFVYAE 226

  Fly   196 PSSADLYTFNGRLELRSGNDGAGSSAGDALPLTIDNLLLRGVRVKSTERVVGCAIYTGMHTKLQL 260
            ..:.|::.|.|......|:.....|      |:|:|.|.... |.::..|||..||||...:..:
Zfish   227 EPNIDIHNFIGTFTREDGDPPVNES------LSIENTLWAST-VIASGTVVGVVIYTGKELRSVM 284

  Fly   261 NSRYTGNKSASSEKYINRFMVALIVGMIVVVVVLYLIERHKEAKIVPTMPYQGPPTNFNSAW--Q 323
            |:....:|....:..:| .:..::.|.:|||.::.:..:|                 |...|  |
Zfish   285 NTSNPRHKIGLFDLEVN-CLTKILFGALVVVSLVMVALQH-----------------FAGRWYLQ 331

  Fly   324 IFEDFLSFLLLFNYMVPISAYMNIEVYRIFGMHFMHNDLHLYDEETDQPCRVNASNLNEELGQVN 388
            ||.    |||||:.:||||..:|:::.::.....:..|..:      ....|.||.:.|:||:::
Zfish   332 IFR----FLLLFSNIVPISLRVNLDMGKMVFSWMIKKDSKI------PGTVVRASTIPEQLGRIS 386

  Fly   389 ILFSDKTGTLTKNLMKFVNCYVPGTNYQLQN-----THLVSEGTDEKFELEKLDADAAV------ 442
            .|.:|||||||:|.|.|...::....|.:.:     :|:.|..|....:|:...|..|.
Zfish   387 YLLTDKTGTLTQNEMVFRRLHLGTVAYGMDSMDEVQSHVFSAYTQPPQDLQASRAPGATKVRKTI 451

  Fly   443 ------LFEALAVCHTVEVLQEVGDKTLESSESVSEQSHLMSRNIVDRYQASSPDEKALLEGCAS 501
                  ..:|:|:.|.|..:.|....|   .::.:||.:..:..:   ||||||||.:|::...|
Zfish   452 SSRVHEAVKAIALVHNVTPVYEANGVT---DQAEAEQHYEDTCRV---YQASSPDEVSLVQWTES 510

  Fly   502 LGLVYEGQENDVLSICRYPSAEKVQFKRLHVLEFSSERQRMSVIVRDQS-DTIWLYSKGAESAIF 565
            :||...|::...:.: |.||.:.:.|..|.:..|:.|.:||.:||||:| ..|..|.|||:..:
Zfish   511 VGLTLVGRDQSSMQL-RTPSGQILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGADVVM- 573

  Fly   566 PRCKASPLVEQTD---AQITKYAQNGLRTMAVGRRMLTDDELFHFEELYRKANTQLSNRNELIAS 627
                 :.:|:..|   .:....|:.|||.:.|.::.||:::...||..|.:|...:.:|:..:|:
Zfish   574 -----AGIVQYNDWLEEECGNMAREGLRVLVVAKKSLTEEQYQDFEARYVQAKLSVHDRSLKVAT 633

  Fly   628 CYETVENELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAYNIGLACRHIPRGSK 692
            ..|::|.|::||..|.:||.||..|..|||.|:.||:|:|:|||||:|||.........:.|...
Zfish   634 VIESLEMEMELLCLTGVEDQLQADVRPTLEILRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQD 698

  Fly   693 QHFIINTTEPAELLARLDMIGDDEPEVLIVDGTTITALLEHTPRQFADLALRCRAVLCCRLSPLQ 757
            .|.....|..:|....|:.........|::.|.::...|::...:|.:||.:|.||:|||.:|.|
Zfish   699 IHVFRPVTTRSEAHLELNAFRRKHDCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQ 763

  Fly   758 KSEIVTLIKRRKKYITAAIGDGANDVSMIQEAHIGIGITGREGKQAARCADFSIARFEMLRRLFL 822
            |::||.|::.|...:|.|:|||.|||||||||..|:|:.|:|||||:..|||||.:|:.|.||.:
Zfish   764 KAQIVRLLQERTGKLTCAVGDGGNDVSMIQEADCGVGVEGKEGKQASLAADFSITQFKHLGRLLM 828

  Fly   823 VHGHYNSQRLAFLVLFYCYKNIIITGCMALYQVYDLYSATNVYNSIYLWLFDIVYISFSFTVLAI 887
            |||..:.:|.|.|..|..::::.|:...|::.....:::..:|....:..:..:|..|....| :
Zfish   829 VHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSL-V 892

  Fly   888 CDKDYSEETLLSHPELYKPLAHNRQASMGVFSLWILNGFVQCFIIFFFTYAMLNDANVLFNGGQT 952
            .|||...|..:.:|||||.|...|..|...|.:|:|....|..||.:       .|.:||.
Zfish   893 LDKDVKSEVAMLYPELYKDLLKGRPLSFKTFLIWVLISIYQGSIIMY-------GALLLFE---- 946

  Fly   953 ASFQTFGTMLITIIVIVGNLKLLLVAHYMTYRNFAMILASIAAFMLTTYLYNLYTSGELYDVYNQ 1017
            :.|.....:..|.:::.   :||:||..:...::.||:|.:.:  |..|:.:|....|..|||
Zfish   947 SEFVHIVAISFTSLILT---ELLMVALTIQTWHWLMIVAELLS--LACYIASLVFLHEFIDVY-- 1004

  Fly  1018 FLSSLP-IWLFTIICSVACLLPDFVIK 1043
            |:::|. ||..|.|..::| ||.:::|
Zfish  1005 FIATLSFIWKVTAITLISC-LPLYILK 1030

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9981	NP_001259610.1	PhoLip_ATPase_N	20..66	CDD:292826	18/46 (39%)
		ATPase-Plipid	28..1051	CDD:273734	322/1049 (31%)
		E1-E2_ATPase	84..>189	CDD:278548	36/111 (32%)
		Cation_ATPase	<489..568	CDD:289987	28/79 (35%)
		HAD_like	<758..807	CDD:304363	27/48 (56%)
		PhoLip_ATPase_C	804..1050	CDD:292829	69/241 (29%)
atp9a	XP_005174184.3	P-type_ATPase_APLT_Neo1-like	55..966	CDD:319841	298/979 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578114
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.850