DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9981 and gdf10

DIOPT Version :9

Sequence 1:	NP_001259610.1	Gene:	CG9981 / 32609	FlyBaseID:	FBgn0030746	Length:	1060	Species:	Drosophila melanogaster
Sequence 2:	XP_004915891.1	Gene:	gdf10 / 100485598	XenbaseID:	XB-GENE-5998698	Length:	436	Species:	Xenopus tropicalis

Alignment Length:	197	Identity:	41/197 - (20%)
Similarity:	63/197 - (31%)	Gaps:	68/197 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   384 LGQVNILFSDKTGTLTKNLMKFVNCYVPGTN-YQLQNTHLVSEGTDEKFELE---KLDADAAVLF 444
            ||:.|.:....||.|..   :.|...:|.:: ..|....|.     ||:..|   ..|.:....|
Frog    15 LGRANKVSGASTGKLPP---ERVGSIIPQSDPLSLHMAKLY-----EKYSREGNRPQDGNTVRSF 71

  Fly   445 EALAVCHTV-----EVLQEVGDKTLESSESVSEQSHLMSRNIVDRYQASSPDEKALLEGCASLGL 504
            .|..:..||     ..||:..|....:....|.:..|.||   |.|...|.:
Frog    72 RAQPLSRTVYWFNLTSLQQTEDVVATTLHFASAKGSLSSR---DSYCKRSKN------------- 120

  Fly   505 VYEGQENDVLSICRYPSAEKVQFKRLHVLEFSSERQRMSVIVRD--QSDTI----W-----LYSK 558
                      |.||              |...::.|::|::.|.  |:.|:    |     .|.:
Frog   121 ----------SSCR--------------LLMPTQHQKISLVFRSVIQNKTLGSEKWNVTSIFYKR 161

  Fly   559 GA 560
            ||
Frog   162 GA 163

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9981	NP_001259610.1	PhoLip_ATPase_N	20..66	CDD:292826
		ATPase-Plipid	28..1051	CDD:273734	41/197 (21%)
		E1-E2_ATPase	84..>189	CDD:278548
		Cation_ATPase	<489..568	CDD:289987	14/83 (17%)
		HAD_like	<758..807	CDD:304363
		PhoLip_ATPase_C	804..1050	CDD:292829
gdf10	XP_004915891.1	TGF_beta_GDF10	325..436	CDD:381664
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165164439
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930