Protein Alignment mei-41 and SH3PXD2B

DIOPT Version :9

• Sequence 1: NP_523369.2
• Gene: mei-41 / 32608
• FlyBaseID: FBgn0004367
• Length: 2517
• Species: Drosophila melanogaster
• Sequence 2: XP_016864840.1
• Gene: SH3PXD2B / 285590
• HGNCID: 29242
• Length: 939
• Species: Homo sapiens
• Alignment Length: 499
• Identity: 98/499 - (19%)
• Similarity: 163/499 - (32%)
• Gaps: 139/499 - (27%)

  Fly  1093 FLDRMENVSPSIQKCIRRHTAHLDLK-----GLAEEENQSPPLVDQLRFLQKHITDECLQVRVYA 1152
            ::.|:...|.|.:...||::...||:     ....|..|..|....:.||...|        ::.
Human    27 YIIRVTWSSGSTEAIYRRYSKFFDLQMQMLDKFPMEGGQKDPKQRIIPFLPGKI--------LFR 83

  Fly  1153 LQHLGDLFGRRRPKLNSTILSELPLEPMLEQIVNVLMAGCQHDDSQLQMASAKCLGELGAIDASY 1217
            ..|:.|:..:|...::....:.:.|.|.:.|        |   |..||....:
Human    84 RSHIRDVAVKRLIPIDEYCKALIQLPPYISQ--------C---DEVLQFFETR------------ 125

  Fly  1218 LPSNYNFASPQHLPL-----NILSDDFAVLALTSLCRGYQFQQNTKHVDSFSLAIQETLAICGIS 1277
             |.:.|....:|:..     :..|.|..||....:...||.|::::    .||::.:.:.|.
Human   126 -PEDLNPPKEEHIGKKKSGGDQTSVDPMVLEQYVVVANYQKQESSE----ISLSVGQVVDII--- 182

  Fly  1278 PKEQKKVQLWQSLPARMRQLMEPMLHSCYTCVHRPSTCLQ-----------QPLFGSHYSHNYYE 1331
              |:.:...|....|..:..:             |:|||:           ||           |
Human   183 --EKNESGWWFVSTAEEQGWV-------------PATCLEGQDGVQDEFSLQP-----------E 221

  Fly  1332 E--WAFLWASRLIDYLPSS-GRRHLLSSYKPCIKRDSNMLSTFYPYILLHALLECTTEQRNHIQE 1393
            |  |.: |:      ||.. |||..|........|.....:..|||         |...::.:..
Human   222 EVSWRY-WS------LPRPVGRRRTLGDLYAISWRQEEKYTVIYPY---------TARDQDEMNL 270

  Fly  1394 E---FMAVLQANEESSSSVR-----GRQELGAIKENAFKQF--------ESRKYAAGIKPLA--S 1440
            |   .:.|:|.|.|....:|     |......:|:|:.:..        .|...|..:..::  .
Human   271 ERGAVVEVIQKNLEGWWKIRYQGKEGWAPASYLKKNSGEPLPPKPGPGSPSHPGALDLDGVSRQQ 335

  Fly  1441 TLVSDRKE--DSSRVPRLAGKLCAELLDFLQRWLREWQRIHGRSTGGKP----------PETIDS 1493
            ..|...||  .|.|..|..|:...: .|..||..:..||...|.....|          |..::.
Human   336 NAVGREKELLSSQRDGRFEGRPVPD-GDAKQRSPKMRQRPPPRRDMTIPRGLNLPKPPIPPQVEE 399

  Fly  1494 NYRKIHEFLNLIPKLLVSRASYNCGEYARALS---YLESYLEEG 1534
            .|..|.||...||..:..:|........:.||   |::...:||
Human   400 EYYTIAEFQTTIPDGISFQAGLKVEVIEKNLSGWWYIQIEDKEG 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mei-41	NP_523369.2	UME	955..1060	CDD:214825
		FAT	1653..1985	CDD:280429
		PIKKc_ATR	2181..2448	CDD:270625
		FATC	2486..2517	CDD:280430
SH3PXD2B	XP_016864840.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900