Protein Alignment mei-41 and Sh3pxd2b

DIOPT Version :9

• Sequence 1: NP_523369.2
• Gene: mei-41 / 32608
• FlyBaseID: FBgn0004367
• Length: 2517
• Species: Drosophila melanogaster
• Sequence 2: XP_006514775.1
• Gene: Sh3pxd2b / 268396
• MGIID: 2442062
• Length: 936
• Species: Mus musculus
• Alignment Length: 632
• Identity: 121/632 - (19%)
• Similarity: 206/632 - (32%)
• Gaps: 202/632 - (31%)

  Fly  1093 FLDRMENVSPSIQKCIRRHTAHLDLK-----GLAEEENQSPPLVDQLRFLQKHITDECLQVRVYA 1152
            ::.|:...|.:.:...||::...||:     ....|..|..|....:.||...|        ::.
Mouse    27 YIIRVTWSSGATEAIYRRYSKFFDLQMQMLDKFPMEGGQKDPKQRIIPFLPGKI--------LFR 83

  Fly  1153 LQHLGDLFGRRRPKLNSTILSELPLEPMLEQIVNVLMAGCQHDDSQLQMASAKCLGELGAIDASY 1217
            ..|:.|:..:|...::....:.:.|.|.:.|        |   |..||....:
Mouse    84 RSHIRDVAVKRLIPIDEYCKALIQLPPYISQ--------C---DEVLQFFETR------------ 125

  Fly  1218 LPSNYNFASPQHL--------PLNILSDDFAVLALTSLCRGYQFQQNTKHVDSFSLAIQETLAIC 1274
             |.:.|....:|:        |.::   |..||....:...||.|::::    .||::.:.:.|.
Mouse   126 -PEDLNPPKEEHIGKKKSGNDPTSV---DPMVLEQYVVVADYQKQESSE----ISLSVGQVVDII 182

  Fly  1275 GISPKEQKKVQLWQSLPARMRQLMEPMLHSCYTCVHRPSTCLQ-----------QPLFGSHYSHN 1328
                 |:.:...|....|..:..:             |:|||:           ||
Mouse   183 -----EKNESGWWFVSTAEEQGWV-------------PATCLEGQDGVQDEFSLQP--------- 220

  Fly  1329 YYEEWAFLWASRLIDYLPSS-GRRHLLSSYKPCIKRDSNMLSTFYPYILLHALLECTTEQRNHIQ 1392
              ||.::.:.|     ||.| |||..|........|.....:..|||         |...::.:.
Mouse   221 --EEVSWRYCS-----LPRSVGRRRTLGDLYAISWRQEEKYTVIYPY---------TARDQDEMN 269

  Fly  1393 EE---FMAVLQANEESSSSVRGRQELGAIKENAFKQFESRKYAAGIKPLA--------------- 1439
            .|   .:.|:|.|.|....:|.:.:.|....:..|:.........:.|.:
Mouse   270 LERGAVVEVVQKNLEGWWKIRYQGKEGWAPASYLKKNSGEPLPPKLGPSSPAHSGALDLDGVSRH 334

  Fly  1440 STLVSDRKE--DSSRVPRLAGKLCAELLDFLQRWLREWQRIHGRSTGGKP----------PETID 1492
            ...:...||  ::.|..|..|:|..: .|..||..:..||...|.....|          |..::
Mouse   335 QNAMGREKELLNNQRDGRFEGRLVPD-GDVKQRSPKMRQRPPPRRDMTIPRGLNLPKPPIPPQVE 398

  Fly  1493 SNYRKIHEFLNLIPKLLVSRASYNCGEYARALS---YLESYLEEG------EDKSQR-------- 1540
            ..|..|.||...||..:..:|........::||   |::...:||      .||.::
Mouse   399 EEYYTIAEFQTTIPDGISFQAGLKVEVIEKSLSGWWYIQMEDKEGWAPATFIDKYKKTSSASRPN 463

  Fly  1541 ----LLEQFTFL-------------VEVYGSLRD-PDSVEGAV-----------------QVRSY 1570
                |..:.|.|             .|..|..|. |::..|||                 :..|.
Mouse   464 FLAPLPHEMTQLRLGDAAATENNTGPEAVGPSRPLPEAPHGAVDSGMLWSKDWKGGKEAPRKASS 528

  Fly  1571 DMSV----------TQDILVNRLVERQQDMITSYEQLLSSTDQ-MQP 1606
            |:|.          ||:...: |..|::.:|.|.|:||....| |:|
Mouse   529 DLSASTGYEEISDPTQEEKPS-LPPRKESIIKSEEELLERERQKMEP 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mei-41	NP_523369.2	UME	955..1060	CDD:214825
		FAT	1653..1985	CDD:280429
		PIKKc_ATR	2181..2448	CDD:270625
		FATC	2486..2517	CDD:280430
Sh3pxd2b	XP_006514775.1	PX_FISH	7..125	CDD:132798	22/116 (19%)
		SH3_Tks4_1	155..209	CDD:213008	13/75 (17%)
		SH3_Tks4_2	252..305	CDD:213009	11/61 (18%)
		SH3_Tks4_3	400..452	CDD:213011	12/51 (24%)
		SH3_Tks4_4	879..934	CDD:212951

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900