Protein Alignment mei-41 and pifk-1

DIOPT Version :9

• Sequence 1: NP_523369.2
• Gene: mei-41 / 32608
• FlyBaseID: FBgn0004367
• Length: 2517
• Species: Drosophila melanogaster
• Sequence 2: NP_508177.2
• Gene: pifk-1 / 180443
• WormBaseID: WBGene00018076
• Length: 666
• Species: Caenorhabditis elegans
• Alignment Length: 603
• Identity: 131/603 - (21%)
• Similarity: 219/603 - (36%)
• Gaps: 160/603 - (26%)

  Fly  1960 NVMVNYA---KSL--RYGSEHVYQSMPRLISLWLDTTESSTNT--EQVKKMNDLLTNCCTALPTA 2017
            |...|:|   |||  |.......||...:|:|.||..|.:..|  ....|....|........:.
 Worm   156 NKYENHALMLKSLLSRSNVPGTSQSADNMITLSLDRLEETNWTVGSSYGKSAGALARAAIQKEST 220

  Fly  2018 VFYTVYSQMLSRLCHPVN-DVFTVLRNVI-------IKLVEAYPQQSLWMLLPHFKSAKAHR--I 2072
            :.....|...|| |.|:: .:.|..:|.|       :||.|           .|..|:|..:  .
 Worm   221 LTAEHDSYEKSR-CGPISTKLLTNQQNFIGRLVYIGVKLTE-----------HHLLSSKQEKTIA 273

  Fly  2073 KRCKLVLTDSRLQNST-----FQKLLQDFNSLTERLMDLTNKE----------VTLDRTYK---- 2118
            .:.:|.:.:|.|.||.     |:..:  ||........|.:|:          :.....|.
 Worm   274 LQSELSMLNSMLPNSVWIPFDFENTM--FNICVNESAVLNSKDKVPYVFFAEVIRSSPNYNSNIK 336

  Fly  2119 -LSDLDTRLSKLCKQPEFSQILLPFEKYMQPTLPLNSDSNSSEGSHLPANQSTVNWFPYQQIYIS 2182
             ||.::.|:    |:.:...:||..:.|...|.|
 Worm   337 TLSSVEPRI----KKSQSESVLLKNKSYHDSTDP------------------------------- 366

  Fly  2183 GFQESVLILRSAAKPKKLTIRCS----DGKDYD---VLVKPKDDLRRDARLMEFNGLVKRYLHQD 2240
                |:.:...:...||..||.|    :.:.:|   |:||..|||.::|...:.....|...|::
 Worm   367 ----SIAVFAESWAEKKARIRGSSRYENHQKWDLIPVIVKTGDDLSQEAFAQQLLFTFKDLWHEE 427

  Fly  2241 APARQRRLHIRTYAVLPFNEECGLVEWLPNLASYRSICMNLYAQRRLVMSTRQLQSLAVPLHESI 2305
            ...    |::|.|.::....:.||:|.:.:..|...|      :|.|....|...::..|   |:
 Worm   428 GVP----LYLRPYKIVCIGSDAGLIEPVLDTLSLHQI------KRHLTNVFRMNGNVTTP---SL 479

  Fly  2306 ERKRE-VFTKQLVPAHPPVFQEWLRQRFATPHSWYEARNTYIRTVAVMSMVGYILGLGDRHGENI 2369
            :...| ||        .||..|          ::..|:..:|::.|..|:|.|.|.|.|||..||
 Worm   480 KHHFENVF--------GPVNSE----------TYVNAQKNFIQSTAAYSLVSYYLQLKDRHNGNI 526

  Fly  2370 LFAEGNGDAVHVDFNCLFNQGELLPYPEVVPFRLTHNMIVAMGPLGVEGS----FRKCCEITLRL 2430
            |. :.:|..:|:|:..|.:........|..||:||..:|..||  |::..    |:......|..
 Worm   527 LL-DMDGHLIHIDYGFLLSSSPRNLGFETAPFKLTTEIIDVMG--GIDSDMFLYFKSLLLRGLMA 588

  Fly  2431 LKQESKTLMSILRPFVYDVGAQT---RKGAATAKITKDVQRIADRLQGHVKRQQANSIPLSTEGQ 2492
            .::..:.::|:..  :...|::.   |.||.|.:        |...:.||.         ||:.|
 Worm   589 ARKHHRRIVSLAE--IMSAGSKMQCFRAGAETVR--------ALEARFHVS---------STDEQ 634

  Fly  2493 VNFLINEATKVDNLASMY 2510
            :..|::  |.|:.....|
 Worm   635 LQQLVD--TLVEGSRDSY 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mei-41	NP_523369.2	UME	955..1060	CDD:214825
		FAT	1653..1985	CDD:280429	9/29 (31%)
		PIKKc_ATR	2181..2448	CDD:270625	65/278 (23%)
		FATC	2486..2517	CDD:280430	7/25 (28%)
pifk-1	NP_508177.2	PI4Kc_III_beta	367..666	CDD:270712	80/339 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900