Protein Alignment mei-41 and BOLA2-SMG1P6

DIOPT Version :9

• Sequence 1: NP_523369.2
• Gene: mei-41 / 32608
• FlyBaseID: FBgn0004367
• Length: 2517
• Species: Drosophila melanogaster
• Sequence 2: NP_001307551.1
• Gene: BOLA2-SMG1P6 / 107282092
• HGNCID: 53563
• Length: 305
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 56/264 - (21%)
• Similarity: 97/264 - (36%)
• Gaps: 71/264 - (26%)

  Fly   814 LTKMLG----FTCVQEFTCKY--HRLLTAMVLPHCIVNPLCKGVLVLIAKQMQKHIGTLFSISFL 872
            :..:||    :|...|.:.:|  .:|...:...|.:.:|  .||..:..:........|:.:  :
Human    53 VVSLLGCRSSWTAAMELSAEYLREKLQRDLEAEHVLPSP--GGVGQVRGETAASETQVLYRV--M 113

  Fly   873 RIYT---HVFLTEEP-ELANSCIELVVSCTQSS------------LQQLMN-----ADVKQTVAE 916
            |..|   .||.:|.. ..||.|:.:::.....|            |.||.|     .|...:|..
Human   114 RCVTAANQVFFSEAVLTAANECVGVLLGSLDPSMTIHCDMVITYGLDQLENCQTCGTDYIISVLN 178

  Fly   917 LLIYFNRNPTFVMRSFQSLLQLSIGSLEELSSQTANAEFANFIAERFLGVITY--FESCLSEPSF 979
            ||       |.::....:.|..|.  :|:|...::...|..:..|:.:..:.:  :::.||
Human   179 LL-------TLIVEQINTKLPSSF--VEKLFIPSSKLLFLRYHKEKEVVAVAHAVYQAMLS---- 230

  Fly   980 EKPLKE----ETLYSLGQIMRFVGSQHVTQFRFKIIAMLSFVHTLQEPRLQRICLKIWHIFL--H 1038
               ||.    ||.|.|     .:|..        ..|:.:.:|:||.|   ..|.:|.|...  |
Human   231 ---LKNIPVLETAYKL-----ILGEM--------TCALNNLLHSLQLP---EACSEIKHEAFKNH 276

  Fly  1039 VVNV 1042
            |.||
Human   277 VFNV 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mei-41	NP_523369.2	UME	955..1060	CDD:214825	23/96 (24%)
		FAT	1653..1985	CDD:280429
		PIKKc_ATR	2181..2448	CDD:270625
		FATC	2486..2517	CDD:280430
BOLA2-SMG1P6	NP_001307551.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900