Protein Alignment Fur2 and YSP3

DIOPT Version :9

• Sequence 1: NP_727963.1
• Gene: Fur2 / 32604
• FlyBaseID: FBgn0004598
• Length: 1682
• Species: Drosophila melanogaster
• Sequence 2: NP_014645.1
• Gene: YSP3 / 854164
• SGDID: S000005529
• Length: 478
• Species: Saccharomyces cerevisiae
• Alignment Length: 500
• Identity: 109/500 - (21%)
• Similarity: 182/500 - (36%)
• Gaps: 122/500 - (24%)

  Fly   221 DFDGVDMFGAFSIPEEAIYTNEFAVNIPAGKQMADVIATKHGFINRGQ-IGSLD--NYYLFQHHH 282
            ||||:..|                        :.::..|:.  :..|: :|..|  |::. :|.|
Yeast    22 DFDGIVRF------------------------IENIDGTRS--VRAGEGLGQHDPGNFHT-EHQH 59

  Fly   283 VSKR----------------SLRSSRKHQGALK----------SENEVKWMQQQHEKVRRKRDGP 321
            |:.:                ||:..:.|...::          :||:..|.........:.:.|.
Yeast    60 VAHKTEFLPYRYVIVFNEDISLQQIQSHMQVVQKDHSTSVGKLTENDAFWRVISSSVSSKSQFGG 124

  Fly   322 YQDLPTYSPYNLLRQHGGYVVDPNPHLSFSPESISLASHSQRMEYRDVSSHFIFPDPLFKEQ--W 384
            ..:.  :....|.|.:.||         |:.|.|.:.|....:::.:..:.....:...:|:  |
Yeast   125 IDNF--FDINGLFRGYTGY---------FTDEIIKIISQDPIIKFVEQETTVKISNSSLQEEAPW 178

  Fly   385 YL--VSKNGGAKDGLDMNVGPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPEASFDINGNDS 447
            .|  ||.....|.|.|:..   ..:...||||...:||.||.|.|.|.....:..|....|...|
Yeast   179 GLHRVSHREKPKYGQDLEY---LYEDAAGKGVTSYVLDTGIDTEHEDFEGRAEWGAVIPANDEAS 240

  Fly   448 DPTPQDNGDNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGGVRML----DGKVNDVVEAQALSLN 508
            |.       |.|||.|||.:.:..|      |||.|..|..|::|    :|.|:||::.... :.
Yeast   241 DL-------NGHGTHCAGIIGSKHF------GVAKNTKIVAVKVLRSNGEGTVSDVIKGIEY-VT 291

  Fly   509 PSHIDIYSASWGPEDDGSTVDGPGPLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSC--NCD 571
            ..||: .|.....|..|||.:.....::...:....:.....|..|..|:||...  |:|  :..
Yeast   292 KEHIE-SSKKKNKEFKGSTANLSLGSSKSLAMEMAVNAAVDSGVHFAIAAGNEDE--DACLSSPA 353

  Fly   572 GYTNSIFTLSIS--SATQAGFKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGSLRPDHICTV 634
            |...|| |:..|  |..:|.|..|      .|....::.|          :::..:.......|:
Yeast   354 GAEKSI-TVGASTFSDDRAFFSNW------GTCVDVFAPG----------INIMSTYIGSRNATL 401

  Fly   635 EHTGTSASAPLAAGICALALEANPELTWRDMQYLVVYTSRPAPLE 679
            ..:|||.::|..|||.:..|...|.   .|.::   :...|:|.|
Yeast   402 SLSGTSMASPHVAGILSYFLSLQPA---PDSEF---FNDAPSPQE 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fur2	NP_727963.1	S8_pro-domain	242..318	CDD:293079	14/104 (13%)
		Peptidases_S8_Protein_convertases_Kexins_Fur in-like	375..674	CDD:173789	78/310 (25%)
		Peptidase_S8	411..700	CDD:278510	72/276 (26%)
		P_proprotein	761..849	CDD:279782
		Furin-like	966..1126	CDD:279142
		FU	970..1013	CDD:238021
		FU	1017..1067	CDD:238021
		FU	1063..1106	CDD:214589
		GF_recep_IV	1068..1232	CDD:291509
		FU	1116..1163	CDD:238021
		FU	1211..1255	CDD:214589
		FU	1259..1301	CDD:214589
		FU	1304..1348	CDD:214589
		FU	1356..1403	CDD:238021
		FU	1401..1444	CDD:214589
YSP3	NP_014645.1	Inhibitor_I9	70..167	CDD:283552	15/107 (14%)
		AprE	79..>434	CDD:224322	93/408 (23%)
		Peptidases_S8_PCSK9_ProteinaseK_like	178..451	CDD:173790	79/305 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1404
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810