Protein Alignment Fur2 and TPP2

DIOPT Version :10

• Sequence 1: NP_727963.1
• Gene: Fur2 / 32604
• FlyBaseID: FBgn0004598
• Length: 1682
• Species: Drosophila melanogaster
• Sequence 2: NP_193817.2
• Gene: TPP2 / 827833
• AraportID: AT4G20850
• Length: 1380
• Species: Arabidopsis thaliana
• Alignment Length: 942
• Identity: 203/942 - (21%)
• Similarity: 307/942 - (32%)
• Gaps: 299/942 - (31%)

  Fly   177 VGLGGERAGQAETISGGKYDYNYENTHTNASA-------KDEI-----VERQSNSLDFDG----V 225
            ||.||...|.|  :.||..:.:..|...|.|.       |.||     :|...   ::||    :
plant    82 VGCGGGGGGGA--VGGGAENASVANFKLNESTFIASLMPKKEIRADCFIEAHP---EYDGRGVVI 141

  Fly   226 DMFGAFSIPEEAIYTNEFAVNIPA-GK-QMADVI---------------ATKHGFINRG------ 267
            .:|.:...|..|      .:::.: || ::.|||               |.:.|.| ||
plant   142 AIFDSGFDPSAA------GLHVTSDGKPKVLDVIDCTGSGDIDTSTVVKANEDGHI-RGASGATL 199

  Fly   268 -------------QIGSLDNYYLFQHHHVS--KRSLRSS--RKHQGAL-KSENEVKWMQQQHEKV 314
                         ::||...|.||.....|  |:..|.|  .|:|..: |:.|.:....|:|.||
plant   200 VVNSSWKNPTGEWRVGSKLVYQLFTDDLTSRVKKERRKSWDEKNQEEIAKAVNNLYDFDQKHSKV 264

  Fly   315 R-RKRDGPYQDLPTYSPYNLLRQHGGYVVDPNP--------------------HLSFSPESISLA 358
            . .|.....:||  .|..:.|::......|..|                    .|...|:|..||
plant   265 EDAKLKKTREDL--QSKVDFLKKQADKYEDKGPVIDAVVWHDGEVWRVALDTQSLEEDPDSGKLA 327

  Fly   359 SHSQRMEYRDVSSHFIFPDPLFKEQWYLVSKNGGAKDGLDMNVGPAWQKGYTGKGVVVSILDDGI 423
            ..|....||                   :.:..|....||   ..::......:|.|:||:
plant   328 DFSPLTNYR-------------------IERKYGVFSRLD---ACSFVANVYDEGKVLSIV---- 366

  Fly   424 QTNHPDLAQNYDPEASFDINGNDSDPTPQDNGDNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGG 488
                                 .||.|         |||..||...|.........|||..|.|..
plant   367 ---------------------TDSSP---------HGTHVAGIATAHHPEEHLLNGVAPGAQIIS 401

  Fly   489 VRMLDGKVNDVVE----AQALSLNPSH-IDIYSASWGP----EDDGSTVDGPGPLARRAFIYGVT 544
            .::.|.::..:..    .:||.....| .|:.:.|:|.    .|.|..||            .||
plant   402 CKIGDSRLGSMETGTGLTRALIAALEHNCDLVNMSYGEPALLPDYGRFVD------------LVT 454

  Fly   545 SGRQGKGSIFVWASGNGGRYTDSCNC-DGYTNSIFTLS--ISSATQAGFKPWYLEECSSTLATTY 606
            .....:..|||.::||.|....:... .|.|:||..:.  :|.|..||... .:|..|..|..|:
plant   455 EAVNKRRLIFVSSAGNSGPALTTVGAPGGTTSSIIGVGAYVSPAMAAGAHS-VVEPPSEGLEYTW 518

  Fly   607 SSGTP--GHDKSVATVDMDGSLRPDHICTVEH----TGTSASAPLAAGICALALEA--------N 657
            ||..|  ..|..|......|::.|....|::.    .|||.::|.|.|..||.|.|        :
plant   519 SSRGPTSDGDLGVCISAPGGAVAPVPTWTLQRRMLMNGTSMASPSACGAIALLLSAMKAEGIPVS 583

  Fly   658 PELTWRDMQYLVVYTSRPAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAEQWTSVPPQHI 722
            |....|.::    .||.|.....|:..|.           |.|||.........:|:...|
plant   584 PYSVRRALE----NTSTPVGDLPEDKLTT-----------GQGLMQVDKAYEYLKQFQDYP---- 629

  Fly   723 C---KSRENNEDRKIDGAYGSTL------------STHMDVNGCAGTINEVRYLEHVQCRITLRF 772
            |   :.:.|...:.|..:.|..|            :..:|.....|..|....:...:| :.|..
plant   630 CVFYQIKVNLSGKTIPTSRGIYLREGTACRQSTEWTIQVDPKFHEGASNLKELVPFEEC-LELHS 693

  Fly   773 FPRGNLRI---LLTSPMGTTSTLLFERPRDIVKSNFDDWPFLSVHFWGE-----KAEGRWTL--- 826
            ...|.:|:   ||.:..|....::.:      .:|..|    .||::..     ||..|..|
plant   694 TDEGVVRVPDYLLLTNNGRGFNVVVD------PTNLGD----GVHYFEVYGIDCKAPERGPLFRI 748

  Fly   827 -QVINGGRRRVNQPGILSKWQLIF---------------------------YGTSTQ-------- 855
             ..|...:...|||.::|..|:.|                           :.|:.:
plant   749 PVTIIIPKTVANQPPVISFQQMSFISGHIERRYIEVPHGATWAEATMRTSGFDTTRRFYIDTLQV 813

  Fly   856 -PMR--LKSELLNSSPQLRSPSSSNPFLFPSASNIGQPANEG-GNFNTDSFAS----YLNYQNIF 912
             |:|  :|.|   |:|...|||:.: |:||..|  ||..... ..|.:....|    .::::..|
plant   814 CPLRRPIKWE---SAPTFASPSAKS-FVFPVVS--GQTMELAIAQFWSSGLGSREPTIVDFEIEF 872

  Fly   913 SSAGSDPEPATATLDGQNVTAAIAGGSSAESL 944
            ...|.|.|  ...|||......:    .||:|
plant   873 HGVGVDKE--ELLLDGSEAPIKV----EAEAL 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fur2	NP_727963.1	S8_pro-domain	242..318	CDD:465126	27/117 (23%)
		Peptidases_S8_Protein_convertases_Kexins_Fur in-lik	375..674	CDD:173789	73/324 (23%)
		P_proprotein	761..849	CDD:460225	21/99 (21%)
		GF_recep_IV	970..1073	CDD:464344
		VSP	1020..1379	CDD:146106
		FU	1401..1444	CDD:214589
TPP2	NP_193817.2	Peptidases_S8_Tripeptidyl_Aminopeptidase_II	116..598	CDD:173796	125/566 (22%)
		TPPII	897..1080	CDD:463636	1/2 (50%)