DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fur2 and RSPO2

DIOPT Version :9

Sequence 1:NP_727963.1 Gene:Fur2 / 32604 FlyBaseID:FBgn0004598 Length:1682 Species:Drosophila melanogaster
Sequence 2:XP_011515320.1 Gene:RSPO2 / 340419 HGNCID:28583 Length:250 Species:Homo sapiens


Alignment Length:264 Identity:64/264 - (24%)
Similarity:86/264 - (32%) Gaps:94/264 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly  1235 CPPNRLLEQSRCVSGCREGFFVEAGSLCSPCLHTCSQCVSRTNCSNCSKGLEL--------QNGE 1291
            |..||.....|..|...:..:| :..:|..||    .|.....||.|.:.|..        |.||
Human    21 CQGNRWRRSKRGGSLSAKASYV-SNPICKGCL----SCSKDNGCSRCQQKLFFFLRREGMRQYGE 80

  Fly  1292 CRTTCADGYYS----DRGICAKCYL-SCHTCSGPRRNQCVQCPAGWQLAAGECHPECPEGFYKSD 1351
            |..:|..|||.    |...||:|.: :|.:|..  ::.|.:|..|:.|..|.|..|||:||    
Human    81 CLHSCPSGYYGHRAPDMNRCARCRIENCDSCFS--KDFCTKCKVGFYLHRGRCFDECPDGF---- 139

  Fly  1352 FGCQKCHHYCKTCNDAGPLACTSCPPHSMLDGGLCMECLSSQYYDTTSATCK--------TCHDS 1408
                            .||..|             |||:..         |:        ||..:
Human   140 ----------------APLEET-------------MECVEG---------CEVGHWSEWGTCSRN 166

  Fly  1409 CRSC-FGPGQFSCKGCVPPLHLDQLNSQCVSCCQNQTLAEKTSSAACCNCDGETGECKAT---ST 1469
            .|:| |..|            |:....|.|.        :.......|....|:..||.|   ..
Human   167 NRTCGFKWG------------LETRTRQIVK--------KPVKDTILCPTIAESRRCKMTMRHCP 211

  Fly  1470 GGKR 1473
            ||||
Human   212 GGKR 215

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fur2NP_727963.1 S8_pro-domain 242..318 CDD:293079
Peptidases_S8_Protein_convertases_Kexins_Fur in-like 375..674 CDD:173789
Peptidase_S8 411..700 CDD:278510
P_proprotein 761..849 CDD:279782
Furin-like 966..1126 CDD:279142
FU 970..1013 CDD:238021
FU 1017..1067 CDD:238021
FU 1063..1106 CDD:214589
GF_recep_IV 1068..1232 CDD:291509
FU 1116..1163 CDD:238021
FU 1211..1255 CDD:214589 5/19 (26%)
FU 1259..1301 CDD:214589 14/49 (29%)
FU 1304..1348 CDD:214589 15/44 (34%)
FU 1356..1403 CDD:238021 6/46 (13%)
FU 1401..1444 CDD:214589 10/51 (20%)
RSPO2XP_011515320.1 Furin-like_2 47..151 CDD:292535 39/142 (27%)
FU 106..149 CDD:238021 18/77 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1404
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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