DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fur2 and Rspo4

DIOPT Version :9

Sequence 1:NP_727963.1 Gene:Fur2 / 32604 FlyBaseID:FBgn0004598 Length:1682 Species:Drosophila melanogaster
Sequence 2:NP_001035779.1 Gene:Rspo4 / 228770 MGIID:1924467 Length:228 Species:Mus musculus


Alignment Length:196 Identity:51/196 - (26%)
Similarity:70/196 - (35%) Gaps:51/196 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly  1072 NCASCQ--DHPEYCTSCDHHL--------VMHEHKCYSACPLDTY---ETEDNKCAFCHSTCATC 1123
            ||..|.  .....|::|...|        :....||...|||..:   ..|.|:|..|.:||.:|
Mouse    34 NCTGCVICSEENGCSTCQQRLFLFIRREGIRQYGKCVHDCPLGFFGIRGQEANRCKKCGATCESC 98

  Fly  1124 NGPTDQD-CITCRSSRYAWQNKCLISCPDGFYADKKRLECMPCQEGCK--------TCTSNGVCS 1179
               ..|| ||.|:...:.::.|||.|||.|....:...|   |||.|:        .|..||  .
Mouse    99 ---FSQDFCIRCKRRFHLYKGKCLPSCPPGTLTHQSTRE---CQEECEPSPWGSWSPCIHNG--K 155

  Fly  1180 ECLQNWTLNKRDKCIVSGSEGCSESEFYSQVEGQCRPCHASCGSCNGPADTSCTSCPPNRLLEQS 1244
            .|...|.|..|.:     ..|.::.|              ...||...:::  ..||..||....
Mouse   156 TCGSGWGLETRVR-----EAGPAKQE--------------ETASCRVLSES--RKCPIKRLCPGE 199

  Fly  1245 R 1245
            |
Mouse   200 R 200

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fur2NP_727963.1 S8_pro-domain 242..318 CDD:293079
Peptidases_S8_Protein_convertases_Kexins_Fur in-like 375..674 CDD:173789
Peptidase_S8 411..700 CDD:278510
P_proprotein 761..849 CDD:279782
Furin-like 966..1126 CDD:279142 18/66 (27%)
FU 970..1013 CDD:238021
FU 1017..1067 CDD:238021
FU 1063..1106 CDD:214589 11/43 (26%)
GF_recep_IV 1068..1232 CDD:291509 46/181 (25%)
FU 1116..1163 CDD:238021 17/47 (36%)
FU 1211..1255 CDD:214589 7/35 (20%)
FU 1259..1301 CDD:214589
FU 1304..1348 CDD:214589
FU 1356..1403 CDD:238021
FU 1401..1444 CDD:214589
Rspo4NP_001035779.1 Furin-like_2 35..138 CDD:292535 32/108 (30%)
FU 85..128 18/45 (40%)
FU 85..126 CDD:214589 17/43 (40%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 193..228 3/8 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1404
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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