DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fur2 and rspo3

DIOPT Version :9

Sequence 1:NP_727963.1 Gene:Fur2 / 32604 FlyBaseID:FBgn0004598 Length:1682 Species:Drosophila melanogaster
Sequence 2:NP_001017358.1 Gene:rspo3 / 100007702 ZFINID:ZDB-GENE-030131-9814 Length:317 Species:Danio rerio


Alignment Length:281 Identity:72/281 - (25%)
Similarity:100/281 - (35%) Gaps:79/281 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly  1081 EYCTSCDHHLVMH----------EHKCYSACPLDTYETEDNKCAFCHSTCATCNGPTDQDCITCR 1135
            || |:|.||...|          ...|...|                .||:..||     |:||:
Zfish    16 EY-TNCQHHGSRHRGNKQVSGVSSQGCQGGC----------------QTCSVYNG-----CLTCK 58

  Fly  1136 SSRYAWQNK--------CLISCPDGFYADKK--RLECMPCQEGCKTCTSNGVCSECLQNWTLNKR 1190
            ...:....:        ||.|||:|||..:.  |.:|:.|...|.:|.:...|..|.....|:| 
Zfish    59 PKLFIHLERDGMRQIGVCLASCPNGFYGTRSPDRNDCIKCGSECDSCFNRNFCLRCRAGSYLHK- 122

  Fly  1191 DKCIVSGSEGCSESEFYSQVEGQC-RPCHASCGSCNGPADTSCTSCPPNRLLEQSRCVSGCREGF 1254
            .||:    |.|.:....|..:.:| ..|.|.|..|.. :|| ||.|.|...|...:|...|.:.|
Zfish   123 GKCM----ESCPDGLVPSDTKKECVAACPALCDLCQN-SDT-CTRCVPGHFLHAGQCHHVCPDEF 181

  Fly  1255 FVEAGSLCSPCLHTC--SQCVSRTNCSNCSK------GLE------LQN-----GECRTTCADGY 1300
            .......|.|.:| |  |:......||...|      |.|      |||     ..|..|     
Zfish   182 EPNDSMECIPTVH-CEVSEWSEWGTCSRSGKTCGFKWGEETRTRKVLQNPSPMGSPCPPT----- 240

  Fly  1301 YSDRGICAKCYLSCHTCSGPR 1321
             |::   .:|::....|..|:
Zfish   241 -SEK---RECFVKKKRCKPPK 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fur2NP_727963.1 S8_pro-domain 242..318 CDD:293079
Peptidases_S8_Protein_convertases_Kexins_Fur in-like 375..674 CDD:173789
Peptidase_S8 411..700 CDD:278510
P_proprotein 761..849 CDD:279782
Furin-like 966..1126 CDD:279142 12/54 (22%)
FU 970..1013 CDD:238021
FU 1017..1067 CDD:238021
FU 1063..1106 CDD:214589 9/34 (26%)
GF_recep_IV 1068..1232 CDD:291509 45/171 (26%)
FU 1116..1163 CDD:238021 16/56 (29%)
FU 1211..1255 CDD:214589 14/44 (32%)
FU 1259..1301 CDD:214589 15/60 (25%)
FU 1304..1348 CDD:214589 3/18 (17%)
FU 1356..1403 CDD:238021
FU 1401..1444 CDD:214589
rspo3NP_001017358.1 FU 1 34..86 16/72 (22%)
Furin-like_2 42..143 CDD:292535 30/126 (24%)
FU 2 92..135 13/47 (28%)
FU 97..143 CDD:238021 12/50 (24%)
FU 3 139..183 15/45 (33%)
TSP1 197..250 CDD:214559 13/61 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 251..317 2/7 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1404
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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