DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nonA and raver2

DIOPT Version :9

Sequence 1:	NP_727962.1	Gene:	nonA / 32603	FlyBaseID:	FBgn0004227	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	XP_001338083.4	Gene:	raver2 / 797613	ZFINID:	ZDB-GENE-090713-1	Length:	862	Species:	Danio rerio

Alignment Length:	272	Identity:	70/272 - (25%)
Similarity:	114/272 - (41%)	Gaps:	26/272 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   286 ELEPVEV-----PTETKFSGRNRLYVGNLTNDITDDELREMFKPYGEISEIFSNLDKNFTFLKVD 345
            ||||.|:     .|..:.|.|.::.:.||..|.|:.|:.|:.:.| |:...|.:.:|...|:.:.
Zfish    73 ELEPEEIEKRLEKTRRELSNRRKILIKNLPQDTTNQEVHEILREY-ELKYCFVDRNKGTAFVTLL 136

  Fly   346 YHPNAEKAKRALDGSMRKGRQLRVRFAPNATILRVSNLTPFVSNELLYKSFEIFGPIERASITVD 410
            ....|:.|.|.|..:..:||.:.|:..|..::|.|:||...|:.....:....:|.|||..:...
Zfish   137 NGDQAQDAIRTLHQTSVRGRDINVQLQPTDSLLCVTNLPYTVTATQFQELVRSYGNIERCFLVYS 201

  Fly   411 D-RGKHMGEGIVEFAKKSSASACLRMCNEKCFFLTASLRPCLVDPMEVNDDT--DGLPEKAF-NK 471
            | .|...|.|.||:.||.|||    ....:........|..:|...:||..|  |.|..|.. ..
Zfish   202 DLTGHSKGYGFVEYMKKDSAS----RARSELLGKPMGDRVLMVQWADVNQLTSADHLHSKCLCVD 262

  Fly   472 KMP-DFNQERSIGPRFADPNSFEHEYGSRWKQLHNLFKTKQDALKRELKMEEDKLEAQMEYARYE 535
            ::| ||.          |.....|.:...:|.:.......:.:..|...:.|.:...|.|....|
Zfish   263 RLPLDFE----------DSEELAHIFSESYKPVFCQLAQDEGSPVRGFAVVEYETAEQAEAVLLE 317

  Fly   536 QETELLR-QELR 546
            .:.:|:: ||:|
Zfish   318 MDRQLIQGQEIR 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nonA	NP_727962.1	RRM1_p54nrb_like	301..371	CDD:240778	19/69 (28%)
		RRM2_p54nrb_like	377..456	CDD:240779	22/79 (28%)
		NOPS_NONA_like	447..546	CDD:240580	22/103 (21%)
		GBP_C	<508..613	CDD:303769	9/40 (23%)
		coiled coil	584..595	CDD:293879
		coiled coil	603..613	CDD:293879
raver2	XP_001338083.4	RRM1_RAVER2	95..164	CDD:241108	18/69 (26%)
		RRM2_RAVER2	168..244	CDD:241110	22/79 (28%)
		RRM_SF	255..352	CDD:327398	16/85 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589405
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840