Protein Alignment nonA and Rbm15

DIOPT Version :10

• Sequence 1: NP_727962.1
• Gene: nonA / 32603
• FlyBaseID: FBgn0004227
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: NP_001386490.1
• Gene: Rbm15 / 684233
• RGDID: 1592713
• Length: 962
• Species: Rattus norvegicus
• Alignment Length: 753
• Identity: 136/753 - (18%)
• Similarity: 261/753 - (34%)
• Gaps: 225/753 - (29%)

  Fly     1 MESAGKQDNNATQQLPQRQ---QRGNQQANKNLGKHNAQKQND---------SADGGPAEKKQRF 53
            |.|||:      :.||:|.   :|.:.....:.|...:|.:.|         ..:..|.:.|:..
  Rat     1 MRSAGR------EPLPRRSPRWRRASPLCETSAGWRVSQLRRDDLRRPSTMKGKERSPVKPKRSR 59

  Fly    54 GGPNAQNQNQNQNQNGGVTGGGGAVGGPNQNKNFGNNKGGFVGNRNRNNNRAGNQNRTFPGNNNP 118
            ||.::.::.:...:.||..|..|:..|...:   |.::...  :.:::::|.|::
  Rat    60 GGEDSSSRGERSKKLGGSGGSNGSSSGKTDS---GGSRRSL--HLDKSSSRGGSR---------- 109

  Fly   119 NQKPNNETSKADGPNALAKNNEPAT---AAAGQNQANQNANKGQNQRQGQNQNQNQVHGQGNQGG 180
                ..:|......:.|...:.|:|   :..|:::::.....|:::..|           .....
  Rat   110 ----EYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSG-----------AASSA 159

  Fly   181 PGNQGGA----------GNQ-GGQGNQGGAGNQ---------------GNGQG--------FR-- 209
            ||...|.          |:| ..:..:.|..::               |:|.|        ||
  Rat   160 PGGGDGVEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRP 224

  Fly   210 --GRNAGNNQGG-GFSGGP---------QNQQRDNRNRSGPRPGGGAGGAMNSTNMGGGGGGGG- 261
              .|.|.:.:|. .....|         :.:.|...::....|.....|:...::....|||||
  Rat   225 EDARAAKHARGRLVLYDRPLKIEAVYVSRRRSRSPLDKDTYAPSSSVVGSSVGSHRHAPGGGGGQ 289

  Fly   262 -----GGGPRGGEDFFITQ----------------------------RLRSISGPTFELEP---- 289
                 ||...|..|:.:.|                            |:|    |.:.|||
  Rat   290 RSLSPGGAALGYRDYRLQQLALGRLPPPPPPPLPRELERERDYPFYDRVR----PAYSLEPRVGA 350

  Fly   290 ----------VEVPTETKFSGRNRLYVGNLTNDITDDELREMFKPYGEISEI-----FSNLDKNF 339
                      .|:..|........|::|||...:|:::||..|..:|.|:|:     .......:
  Rat   351 GAGAAPFREVDEISPEDDQRANRTLFLGNLDITVTENDLRRAFDRFGVITEVDIKRPSRGQTSTY 415

  Fly   340 TFLKVDYHPNAEKAKRALDGSMRKGRQLRVRF--APNATILRVSNLTPFVSNELLYKSFEIFGPI 402
            .|||.:....:.:||.|:.|.:.....:::.:  |...|.|.|..|.|:|....|.:.|:.||.|
  Rat   416 GFLKFENLDMSHRAKIAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTI 480

  Fly   403 ERASITVDDRGKHMGEGIVEFAKKSSASAC---------------LRM--CNEKCFFLTASLRPC 450
            .    |:|.| |......:::....:|.|.               ||:  .:.:..:....|:|.
  Rat   481 R----TIDYR-KGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPL 540

  Fly   451 LVDPMEVNDDTDGL----PEKAFNKKMPDF---NQERSIGP--RFADPNSFEHEYGSR------- 499
            .:...|:..||.|.    |.::...:.|..   :::|.:.|  .:..|.....|..:|
  Rat   541 PLTHYELVTDTFGHRAPDPLRSARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSARAATSAVT 605

  Fly   500 -WKQLHNLFKTKQDALKRELKMEEDKLEAQMEYARYEQETELLRQELRKREVDNERKKLEWEMRE 563
             ::.|.:|     |..:....::.|:.:..:..:|.:.....|.:|...|.:|          |.
  Rat   606 AYEPLDSL-----DRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLD----------RS 655

  Fly   564 KQAEEMRKREEETMRRHQT-------EMQSHMNRQEED 594
            .:::..||      :||.|       |:.|:.:|...|
  Rat   656 PESDRPRK------QRHCTPSPDRSPELSSNRDRYNSD 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nonA	NP_727962.1	RRM1_p54nrb_like	301..371	CDD:409769	18/74 (24%)
		RRM2_p54nrb_like	377..456	CDD:409770	20/95 (21%)
		NOPS_NONA_like	447..546	CDD:240580	20/115 (17%)
		DUF5401	<499..>618	CDD:375164	20/111 (18%)
		PTZ00121	<508..730	CDD:173412	17/94 (18%)
Rbm15	NP_001386490.1	RRM1_RBM15	168..250	CDD:409969	12/81 (15%)
		RRM2_RBM15	366..452	CDD:409971	20/85 (24%)
		RRM3_RBM15	455..527	CDD:409973	18/76 (24%)
		Metaviral_G	<653..782	CDD:462833	11/51 (22%)
		SPOC_SF	788..955	CDD:459247