DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nonA and rbm14b

DIOPT Version :9

Sequence 1:	NP_727962.1	Gene:	nonA / 32603	FlyBaseID:	FBgn0004227	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	XP_021333123.1	Gene:	rbm14b / 402858	ZFINID:	ZDB-GENE-040426-2455	Length:	560	Species:	Danio rerio

Alignment Length:	159	Identity:	46/159 - (28%)
Similarity:	73/159 - (45%)	Gaps:	17/159 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   303 RLYVGNLTNDITDDELREMFKPYGEISEIFSNLDKNFTFLKVDYHPNAEKAKRALDGSMRKGRQL 367
            :|:||||..|.|.:||..:|:.||::  :..::.:.|.|:.:.....||:|.|.|:|...|||.|
Zfish     8 KLFVGNLALDTTQEELSAIFESYGQV--VSCSVLRQFAFVHLQGEGAAERAIRELNGREFKGRNL 70

  Fly   368 RV---RFAP-NATILRVSNLTPFVSNELLYKSFEIFGPIERASITVDDRGKHMGEGIVEFAKKSS 428
            .|   |..| ::|.:.|.||:...:.|.|.:.|:.||.:....       |..|...|....|..
Zfish    71 VVEESRGRPLHSTKVFVGNLSSMCTTEDLQELFQTFGKVLECD-------KVKGYAFVHMENKED 128

  Fly   429 ASACLRMCNEKCFFLTASLRPCLVDPMEV 457
            |...:...:...|    ..||..|:..:|
Zfish   129 ALQAIEALHGTSF----KGRPLSVELSKV 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nonA	NP_727962.1	RRM1_p54nrb_like	301..371	CDD:240778	25/70 (36%)
		RRM2_p54nrb_like	377..456	CDD:240779	17/78 (22%)
		NOPS_NONA_like	447..546	CDD:240580	4/11 (36%)
		GBP_C	<508..613	CDD:303769
		coiled coil	584..595	CDD:293879
		coiled coil	603..613	CDD:293879
rbm14b	XP_021333123.1	RRM1_CoAA	7..75	CDD:241052	25/68 (37%)
		RRM1_2_CoAA_like	84..149	CDD:240789	16/75 (21%)
		AIR1	<150..>187	CDD:331526	1/4 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910