DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment nonA and Raver2

DIOPT Version :9

Sequence 1:	NP_727962.1	Gene:	nonA / 32603	FlyBaseID:	FBgn0004227	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	XP_038966220.1	Gene:	Raver2 / 362551	RGDID:	1307610	Length:	785	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	73/322 - (22%)
Similarity:	103/322 - (31%)	Gaps:	119/322 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 GNQGGAGNQGGQG--NQGGA----GNQGNGQG--------FRGRNAGNNQG-GGF---------- 221
            |:.|||...|..|  ..|.|    |:.|.|..        ||...||..:. ||.
  Rat    23 GSPGGAVAPGAPGFERPGRARRARGSVGTGSSPTTSPSPRFRRCPAGRGRSIGGVAVQGVSLSSA 87

  Fly   222 ------------------SGGPQNQQRD----------NRNRSGPRPGGGAGGAMNSTNMG---- 254
                              ||.|:.:...          :.:.:|.|..||||.......:|
  Rat    88 PPASVAAAPPPPARPCSASGPPRPRAASPLSLPLRSGLSESAAGRREDGGAGRRRGGPGLGIRTL 152

  Fly   255 ---GGGGGG-----GGGG----PRGGEDFFITQRLRSISGPTFELEPVEVPTETKFSGRNRLYVG 307
               ||||.|     ||||    |.||        ..:.:..|...:|.|.|.|....|:
  Rat   153 CWDGGGGRGARAAPGGGGCAAPPGGG--------CTAAADATGAEQPEENPGEKPAPGQ------ 203

  Fly   308 NLTNDITDDELREMFKPYGEISEIFSNLDKNFTFLKVDYHPNAEKAKRALDGSMR---KGRQLRV 369
                                      .|....|.|      |.|:|:.|:....:   :||:|.|
  Rat   204 --------------------------QLPAFVTLL------NGEQAQSAIQRFHQFSFRGRELTV 236

  Fly   370 RFAPNATILRVSNLTPFVSNELLYKSFEIFGPIERASITVDD-RGKHMGEGIVEFAKKSSAS 430
            :..|...:|.::||....:.|...:....:|.|||..:...: .|...|.|.||:.||..|:
  Rat   237 QLQPTDALLCITNLPVSFTLEEFEELVRAYGNIERCFLVYSEVTGHSKGYGFVEYMKKDFAA 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nonA	NP_727962.1	RRM1_p54nrb_like	301..371	CDD:240778	11/72 (15%)
		RRM2_p54nrb_like	377..456	CDD:240779	16/55 (29%)
		NOPS_NONA_like	447..546	CDD:240580
		GBP_C	<508..613	CDD:303769
		coiled coil	584..595	CDD:293879
		coiled coil	603..613	CDD:293879
Raver2	XP_038966220.1	RRM_SF	<207..240	CDD:418427	10/38 (26%)
		RRM2_RAVER2	244..320	CDD:410067	16/55 (29%)
		RRM3_RAVER2	330..426	CDD:410069
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347819
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930