DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment nonA and Krt9

DIOPT Version :9

Sequence 1:	NP_727962.1	Gene:	nonA / 32603	FlyBaseID:	FBgn0004227	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	NP_703206.2	Gene:	Krt9 / 266717	RGDID:	628785	Length:	662	Species:	Rattus norvegicus

Alignment Length:	550	Identity:	120/550 - (21%)
Similarity:	186/550 - (33%)	Gaps:	166/550 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 GNQGGPGNQGG-----------AGNQGGQ-GNQGGAGNQG------NGQGFRGRNAGNNQGGGFS 222
            |..||.|...|           ||..||: |:..|.|..|      .|.|..|.:.|...|||||
  Rat    19 GGGGGRGASRGSMRSSFSRSSRAGGGGGRFGSSSGFGGGGFSACGTGGGGSFGSSYGGGYGGGFS 83

  Fly   223 GGPQNQQRDNRNR------SGPRPGGGAGGAMNSTNMGGGGGGGGGGGPRGGEDFF--------- 272
            .|..:......:|      ||...|||:||     ..|||.|||.|||..|||...
  Rat    84 AGSSSGMFGGGSRGCFGGGSGGGFGGGSGG-----GFGGGFGGGFGGGSGGGEGSILNTNEKVVM 143

  Fly   273 --ITQRLRSISGPTFELEPVEVPTETKFSGRNRLYVGNLTNDITDDELREMFKPYGE--ISEIFS 333
              :..||.|......|||.                    .|...:.:::|.:...|.  ..:.:|
  Rat   144 QNLNSRLASYMDKVQELEE--------------------DNANLEKQIQEWYSRKGNRVFQKDYS 188

  Fly   334 NLDKNFTFLK---VDYHPNAEKAKRALDGSMRKGRQLRVRFAPNATILR-----VSNLTPFVSNE 390
            :.......||   ||......||...:|.:.......||:.....::.:     ::.|...:.:.
  Rat   189 HYYNTIEDLKDRIVDLTARNNKALIDMDNTRMTLGDFRVKLEMEQSLRQGVDADINGLQKVLDDI 253

  Fly   391 LLYKSFEIFGPIERASITVDDRGKHMGEGIVEFAKKSSASACLRMCNEKCFFLTASLRPCLVDPM 455
            .:.||     .:|....::||..|.:        ||          |.|               .
  Rat   254 NMEKS-----DLEIQFDSLDDELKAL--------KK----------NHK---------------E 280

  Fly   456 EVNDDT---DGLPEKAFNKKMPDFNQERSIGPRFAD----PNSFEHEYGSRWKQLHNLFKTKQDA 513
            |:|..|   ||           |.|.|.::.|. .|    .|....||.      |.:.|.:||
  Rat   281 EMNQLTGQNDG-----------DVNVEINVAPS-TDLTQVLNDMREEYE------HLISKNRQD- 326

  Fly   514 LKRELKMEEDKLEAQMEYARYEQETELLRQELRKREVDNERKKLEWEMREKQAEEMRKREEETMR 578
            :::..:.:..::|.|:..:..|.||.:.:....:..|.....:|:.::..|.|  :.|..|:|..
  Rat   327 IEQHYESKMTQIEQQVTNSGQEMETNMKQVSQLQHSVQELNIELQTQLTTKSA--LEKALEDTKN 389

  Fly   579 RH-------------------QTEMQSHMNRQEEDMLRRQQETLFMKAQQLNSLLD--QQE---- 618
            |:                   |...::....||..:|...:..|..:.:....||:  ||:
  Rat   390 RYCGQLQQIQEQISEMEAQLAQVRAETECQNQEYGLLLSIKTRLEKEIETYRKLLEGGQQDFESS 454

  Fly   619 -----GFGGGGGGNNSTFDNFAGNSNSPFE 643
                 |||.|.|....:..::.|.|...:|
  Rat   455 GAGQIGFGSGKGRQRGSGGSYGGGSGDSYE 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nonA	NP_727962.1	RRM1_p54nrb_like	301..371	CDD:240778	13/74 (18%)
		RRM2_p54nrb_like	377..456	CDD:240779	11/83 (13%)
		NOPS_NONA_like	447..546	CDD:240580	22/105 (21%)
		GBP_C	<508..613	CDD:303769	21/123 (17%)
		coiled coil	584..595	CDD:293879	2/10 (20%)
		coiled coil	603..613	CDD:293879	1/9 (11%)
Krt9	NP_703206.2	Filament	138..450	CDD:365827	68/390 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000