DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nonA and Raver2

DIOPT Version :9

Sequence 1:	NP_727962.1	Gene:	nonA / 32603	FlyBaseID:	FBgn0004227	Length:	742	Species:	Drosophila melanogaster
Sequence 2:	NP_898845.1	Gene:	Raver2 / 242570	MGIID:	2443623	Length:	673	Species:	Mus musculus

Alignment Length:	196	Identity:	54/196 - (27%)
Similarity:	85/196 - (43%)	Gaps:	34/196 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   254 GGGGGGGGGGGPRGGEDFFITQRLRSISGPTFE--LEPVEV----PTET---------KFSGRNR 303
            ||.||.|.|.||..|           .:|...|  |.|.||    |.|.         :.|.|.:
Mouse     6 GGAGGAGSGSGPSAG-----------TAGEAAEPALRPGEVAALHPQEVAARLQRMRRELSNRRK 59

  Fly   304 LYVGNLTNDITDDELREMFKPYGEISEIFSNLDKNFTFLKVDYHPNAEKAKRALDGSMR---KGR 365
            :.|.||..|.:..|:.|:.:.| |:...:.:.:|...|:.:   .|.|:|:.|:....:   :||
Mouse    60 ILVKNLPQDSSSQEVHELLQDY-ELKYCYVDRNKRTAFVTL---LNGEQAQSAIQRFHQFSFRGR 120

  Fly   366 QLRVRFAPNATILRVSNLTPFVSNELLYKSFEIFGPIERASITVDD-RGKHMGEGIVEFAKKSSA 429
            :|.|:..|...:|.::||....:.|...:....:|.|||..:...: .|...|.|.||:.||..|
Mouse   121 ELTVQLQPTDALLCITNLPISFTLEEFEELVRAYGNIERCFLVYSEVTGHSKGYGFVEYMKKDFA 185

  Fly   430 S 430
            :
Mouse   186 A 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nonA	NP_727962.1	RRM1_p54nrb_like	301..371	CDD:240778	19/72 (26%)
		RRM2_p54nrb_like	377..456	CDD:240779	16/55 (29%)
		NOPS_NONA_like	447..546	CDD:240580
		GBP_C	<508..613	CDD:303769
		coiled coil	584..595	CDD:293879
		coiled coil	603..613	CDD:293879
Raver2	NP_898845.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34		13/38 (34%)
		RRM_SF	59..128	CDD:302621	18/72 (25%)
		RRM2_RAVER2	132..208	CDD:241110	16/55 (29%)
		RRM_SF	218..314	CDD:302621
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	481..549
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844444
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840