DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment U2af50 and AT2G33435

DIOPT Version :9

Sequence 1:	NP_001245708.1	Gene:	U2af50 / 32602	FlyBaseID:	FBgn0005411	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_001318342.1	Gene:	AT2G33435 / 817909	AraportID:	AT2G33435	Length:	1325	Species:	Arabidopsis thaliana

Alignment Length:	520	Identity:	139/520 - (26%)
Similarity:	218/520 - (41%)	Gaps:	128/520 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KDRERDRERRRHRSRSRD------------------------RHRERS----RDR--RHHRN--- 46
            |.|:||...:|.||||||                        .|.|||    :||  :||.|
plant   690 KSRQRDLREKRRRSRSRDHGQDRQKRSSPLPRAEKATSRHKRNHEERSENVVKDRSGKHHCNDNE 754

  Fly    47 ----------SRR---------------------------------KPSLYW------------D 56
                      |||                                 |.|..|            |
plant   755 DKVTSTVSNKSRRYSASKSELGGYSPRKRREQASTKAASPPNLSSEKKSAKWGLAATVTAGMFSD 819

  Fly    57 VPPPGFEHITPMQYKAMQASG--QIPASVVPDTPQTAVPVVGST---------ITRQARRLYVGN 110
            ....|.:..|...|..:..:.  .:...:|.|.|....|...:|         .||:.||||..|
plant   820 SVFSGLQAATQTAYPTISEASLTLLKPLMVMDAPFRTPPARQTTSFDSVQLTESTRRMRRLYAEN 884

  Fly   111 IPFGVTEEEMMEFFNQQMHLVGLAQAAGS-PVLACQINLDKNFAFLEFRSIDETTQAMAFDGINL 174
            :|...:|:.::|.||..|...|.....|| |.::|.||.:|:.|.:||.:..:.:.|::.||.:.
plant   885 VPDSASEKSLIECFNGYMLSSGSNHIKGSEPCISCIINKEKSQALVEFLTPQDASAALSLDGCSF 949

  Fly   175 KGQSLKIRRPHDYQPMPGITDTPAIKPAVVSSGVISTVVPDSPHKIFIGGLPNYLNDDQVKELLL 239
            .|.:||||||.||..    |....::....::..:|..|.||.:||||||....::.:.:.|::.
plant   950 AGSNLKIRRPKDYVR----TTNGELEKKEPAANAVSDNVEDSSNKIFIGGFSKAISSEMLMEIVS 1010

  Fly   240 SFGKLRAFNLVKDAATGLSKGYAFCEYVDLSITDQSIAGLNGMQLGDKKLIVQRASVGAKNAQNA 304
            .||.|:|:..|.:  ..|::..||.||.|.|:|.::.||||||:||..   |..|.....:|.:.
plant  1011 VFGPLKAYRFVSN--NDLNQRCAFLEYTDGSVTLKACAGLNGMRLGGS---VITAVCAFPDASSV 1070

  Fly   305 ANTTQSVMLQVPGLSNVVTSGPPTEVLCLLNMVTPDELR--DEEEYEDILEDIKEECTKYGVVRS 367
            |.........:|..:..:. |.|..:|.|.|:|.|::|.  .|:|.::||||::.||.::||::|
plant  1071 AVNENPPFYGIPSHAKPLL-GKPKNILKLKNVVDPEDLTSFSEQEVKEILEDVRLECARFGVIKS 1134

  Fly   368 VEI------------PRPIEGVEVPGCGKVFVEFNSVLDCQKAQQALTGRKFSDRVVVTSYFDPD 420
            :.|            ..|:..:|.....::.|   ||:: :|.:.:......:|.|.:.....||
plant  1135 INILEHKSKDITVSETNPLLNLESTDSKEMNV---SVIE-EKDEGSEKAEDIADNVDLAEVVMPD 1195

Fly 421 420
plant 1196 1195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
U2af50	NP_001245708.1	RRM1_U2AF65	103..184	CDD:240676	30/81 (37%)
		RRM2_U2AF65	218..294	CDD:240677	29/75 (39%)
		RRM3_U2AF65	328..415	CDD:240678	26/100 (26%)
AT2G33435	NP_001318342.1	PTZ00121	<3..783	CDD:173412	23/92 (25%)
		U2AF_lg	681..1137	CDD:273727	128/456 (28%)
		RRM_SF	<1275..1311	CDD:418427
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0120
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23139
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910