Protein Alignment U2af50 and u2af2

DIOPT Version :9

• Sequence 1: NP_001245708.1
• Gene: U2af50 / 32602
• FlyBaseID: FBgn0005411
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_001016998.1
• Gene: u2af2 / 549752
• XenbaseID: XB-GENE-494184
• Length: 465
• Species: Xenopus tropicalis
• Alignment Length: 467
• Identity: 307/467 - (65%)
• Similarity: 356/467 - (76%)
• Gaps: 48/467 - (10%)

  Fly     4 NFEDKYVNIDNKDRERDRERRRH-----RSRSRDR-HRERSRDRR----------HHRNSR---- 48
            :|::....::...:|||:|.|..     ||||||| .|.||||||          ..|.||
 Frog     3 DFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRGREQRSGSRDRRRRSRSPRH 67

  Fly    49 ---RKPSLYWDVPPPGFEHITPMQYKAMQASGQIPA-----SVVPD----TPQTAVPVVGSTITR 101
               :|...||||||||||||||||||||||:|||||     ::.||    || |.||||||.:||
 Frog    68 EKKKKIRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTP-TPVPVVGSQMTR 131

  Fly   102 QARRLYVGNIPFGVTEEEMMEFFNQQMHLVGLAQAAGSPVLACQINLDKNFAFLEFRSIDETTQA 166
            |||||||||||||:|||.||:|||.||.|.||.||.|:||||.|||.|||||||||||:||||||
 Frog   132 QARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQA 196

  Fly   167 MAFDGINLKGQSLKIRRPHDYQPMPGITDTPAIKPAVVSSGVISTVVPDSPHKIFIGGLPNYLND 231
            ||||||..:||||||||||||||:||:::    .|:|...||:|||||||.||:|||||||||||
 Frog   197 MAFDGIIFQGQSLKIRRPHDYQPLPGMSE----NPSVYVPGVVSTVVPDSAHKLFIGGLPNYLND 257

  Fly   232 DQ---------VKELLLSFGKLRAFNLVKDAATGLSKGYAFCEYVDLSITDQSIAGLNGMQLGDK 287
            ||         |||||.|||.|:|||||||:|||||||||||||||:::|||:||||||||||||
 Frog   258 DQVTMESLSLWVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDK 322

  Fly   288 KLIVQRASVGAKNAQNAANTTQSVMLQVPGL--SNVVTSGPPTEVLCLLNMVTPDELRDEEEYED 350
            ||:|||||||||||..:......|.||||||  |.|...|.|||||||:|||.|:||.|::|||:
 Frog   323 KLLVQRASVGAKNATLSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDDEYEE 387

  Fly   351 ILEDIKEECTKYGVVRSVEIPRPIEGVEVPGCGKVFVEFNSVLDCQKAQQALTGRKFSDRVVVTS 415
            |:||:::||.|||.|:|:|||||::|||||||||:||||.||.|||||.|.||||||::|||||.
 Frog   388 IVEDVRDECGKYGAVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTK 452

  Fly   416 YFDPDKYHRREF 427
            |.|||.||||:|
 Frog   453 YCDPDGYHRRDF 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
U2af50	NP_001245708.1	RRM1_U2AF65	103..184	CDD:240676	65/80 (81%)
		RRM2_U2AF65	218..294	CDD:240677	65/84 (77%)
		RRM3_U2AF65	328..415	CDD:240678	62/86 (72%)
u2af2	NP_001016998.1	U2AF_lg	4..464	CDD:273727	306/464 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	131	1.000	Domainoid score	I5132
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H110853
Inparanoid	1	1.050	591	1.000	Inparanoid score	I976
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391481at33208
OrthoFinder	1	1.000	-	-		FOG0003153
OrthoInspector	1	1.000	-	-		oto104663
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1575
SonicParanoid	1	1.000	-	-		X2550
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090