Protein Alignment U2af50 and hfp

DIOPT Version :10

• Sequence 1: NP_001245708.1
• Gene: U2af50 / 32602
• FlyBaseID: FBgn0005411
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_525123.2
• Gene: hfp / 38173
• FlyBaseID: FBgn0028577
• Length: 637
• Species: Drosophila melanogaster
• Alignment Length: 529
• Identity: 97/529 - (18%)
• Similarity: 165/529 - (31%)
• Gaps: 248/529 - (46%)

  Fly   105 RLYVGNIPFGVTEEEMMEFFNQQMHLVGLAQAAGSPVLACQINLD------KNFAFLEFRSIDET 163
            |:|||:|.|.:.|:           .:.:|.....|:.:..::.|      |.|||:|: .|.|.
  Fly   131 RVYVGSISFELKED-----------TIRVAFTPFGPIKSINMSWDPITQKHKGFAFVEY-EIPEG 183

  Fly   164 TQAMAFDGIN---LKGQSLKIRRPHDYQPMPGITDTPAIKPAVVSSGVISTVVPD--SPHKIFIG 223
            .| :|.:.:|   :.|:::|:.||.:   ||            .:..||..|..:  |.::|::.
  Fly   184 AQ-LALEQMNGALMGGRNIKVGRPSN---MP------------QAQQVIDEVQEEAKSFNRIYVA 232

  Fly   224 GLPNYLNDDQVKELLLSFGKLRAFNLVKDAATGLSKGYAFCEYVDLSITDQSIAGLNGMQLGDKK 288
            .:...|:::.:|.:..:||.:....|.:..:....|||.|.||.:....|::||.:|...||.:.
  Fly   233 SIHPDLSEEDIKSVFEAFGPILYCKLAQGTSLHTHKGYGFIEYANKQAMDEAIASMNLFDLGGQL 297

  Fly   289 LIVQRA----------------------------------------------------------- 294
            |.|.|:
  Fly   298 LRVGRSITPPNALACPTTNSTMPTAAAVAAAAATAKIQALDAVASNAVLGLSQNTPVMAAGAVVT 362

  Fly   295 SVGAKNAQNAANTTQSV--------------------------MLQVPG----LSNVVTSGPP-- 327
            .|||....:||.:..::                          :|.||.    |..||.:.||
  Fly   363 KVGAMPVVSAATSAAALHPALAQAAPALLPPGIFQAPTPVAPSLLGVPAGLQPLQAVVPTLPPPA 427

  Fly   328 ----------------------------------------------------------------- 327
                                                                             
  Fly   428 LLATPTLPMTVGGVGVGLVPTVATLAGAEASKGAAAAAALSAAANNAAVTAANLSENIKKAHEKQ 492

  Fly   328 -------------------------------------------TEVLCLLNMVTPDELRDEEEYE 349
                                                       :.|:.|.|||.|:::.     |
  Fly   493 QEELQKKLMDEGDVQTLQQQENMSIKGQSARQLVMQRLMRPVDSRVIILRNMVGPEDVD-----E 552

  Fly   350 DILEDIKEECTKYGVVRSVEI--PRPIEGV---EVPGCGKVFVEFNSVLDCQKAQQALTGRKFSD 409
            .:.|:|:|||:|:|.|..|.|  .:..|..   |.....|:||||::..:..:.::||.||.|..
  Fly   553 TLQEEIQEECSKFGTVSRVIIFNEKQTENEDDDEAEIIVKIFVEFSAGAEAMRGKEALDGRFFGG 617

  Fly   410 RVVVTSYFD 418
            |.||...:|
  Fly   618 RRVVAELYD 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
U2af50	NP_001245708.1	U2AF_lg	<50..427	CDD:273727	97/529 (18%)
hfp	NP_525123.2	half-pint	10..637	CDD:130706	97/529 (18%)