Protein Alignment U2af50 and LS2

DIOPT Version :10

• Sequence 1: NP_001245708.1
• Gene: U2af50 / 32602
• FlyBaseID: FBgn0005411
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_611769.2
• Gene: LS2 / 37681
• FlyBaseID: FBgn0034834
• Length: 449
• Species: Drosophila melanogaster
• Alignment Length: 437
• Identity: 240/437 - (54%)
• Similarity: 297/437 - (67%)
• Gaps: 33/437 - (7%)

  Fly    14 NKDRERDRERRRHRSRSRDRHRERSRDRR-------HHRNSRR--KPSLYWDVPPPGFEHITPMQ 69
            |..|.|.|.|.|.||..|.:...|||..|       ..|..||  :|...||:||.|:.|:||.|
  Fly    12 NALRSRSRSRSRSRSPFRSQSITRSRPTRSDTIYTERTRLQRRFSRPPSSWDIPPEGYNHLTPQQ 76

  Fly    70 YKAMQASGQIPASVVPDTPQTAVPVVGSTITRQARRLYVGNIPFGVTEEEMMEFFNQQMHLVGLA 134
            ||||.|||||.:.::.|..........|.||||||||||||||||||:||||:|||.|:..:|..
  Fly    77 YKAMLASGQIASRILSDGVHGGESAAISMITRQARRLYVGNIPFGVTDEEMMQFFNHQIMALGFE 141

  Fly   135 QAA-----GSPVLACQINLDKNFAFLEFRSIDETTQAMAFDGINLKGQSLKIRRPHDYQPMPGIT 194
            ..:     |:.||.||.||:|||||||||||||.:||:.|||:..:||:|||||||||||:|.|:
  Fly   142 AKSSHYMDGNAVLTCQTNLEKNFAFLEFRSIDEASQALNFDGMVFRGQTLKIRRPHDYQPVPSIS 206

  Fly   195 ----------DTPAI----KPAVVSSGVISTVVPDSPHKIFIGGLPNYLNDDQVKELLLSFGKLR 245
                      ..|||    :|||...  ::|:|||||:||::||||..||.|||||||.|||:|:
  Fly   207 VSAMESYRSFRVPAINVAQQPAVTLP--VTTIVPDSPNKIYVGGLPTCLNQDQVKELLQSFGELK 269

  Fly   246 AFNLVKDAATGLSKGYAFCEYVDLSITDQSIAGLNGMQLGDKKLIVQRASVGAKNAQNAANTTQS 310
            ..|||.|..|.|:||:||.||.|.|:||.:||||:||.|||::|:|||:..|.|||......|
  Fly   270 GLNLVMDTNTNLNKGFAFFEYCDPSVTDHAIAGLHGMLLGDRRLVVQRSIPGGKNAFPGHLPT-- 332

  Fly   311 VMLQVPGLSNVVTSGPPTEVLCLLNMVTPDELRDEEEYEDILEDIKEECTKYGVVRSVEIPRPIE 375
             :|||||:|.:...|.|||.|||||||.|:||.|:||:|||..|||:||.|:|.|||::|||||.
  Fly   333 -VLQVPGISTLQDPGSPTETLCLLNMVRPEELLDDEEFEDIRTDIKQECAKFGEVRSIKIPRPIG 396

  Fly   376 GVEVPGCGKVFVEFNSVLDCQKAQQALTGRKFSDRVVVTSYFDPDKY 422
            .....|||||||:|.||.|.|||.:||:|||||.|:|:|||:||:||
  Fly   397 QFPKRGCGKVFVQFESVEDSQKALKALSGRKFSGRIVMTSYYDPEKY 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
U2af50	NP_001245708.1	U2AF_lg	<50..427	CDD:273727	224/392 (57%)
LS2	NP_611769.2	U2AF_lg	35..447	CDD:273727	231/414 (56%)