Protein Alignment U2af50 and uaf-1

DIOPT Version :10

• Sequence 1: NP_001245708.1
• Gene: U2af50 / 32602
• FlyBaseID: FBgn0005411
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_001022967.1
• Gene: uaf-1 / 175270
• WormBaseID: WBGene00006697
• Length: 496
• Species: Caenorhabditis elegans
• Alignment Length: 453
• Identity: 256/453 - (56%)
• Similarity: 311/453 - (68%)
• Gaps: 59/453 - (13%)

  Fly    15 KDRERDRE-RRRHRSRSR----------DRHRERSRDRRH---------------HRNSRRKPS- 52
            :.|.|||: |||.|||.|          ||.|.|||:||.               ...|||:|.
 Worm    63 RSRSRDRDTRRRSRSRDRGERRGGGGGGDRDRSRSRERRRGGGGRDEPRRRGGDDEARSRREPEP 127

  Fly    53 ---------LYWDVPPPGFEHITPMQYKAMQASGQIPASVVPDTPQTAVPVVGSTITRQARRLYV 108
                     .:|||||.|||..|||:||.|||:||:|...|    |:||||||.::|.|:|||||
 Worm   128 QKPREPKKYRFWDVPPTGFETTTPMEYKNMQAAGQVPRGSV----QSAVPVVGPSVTCQSRRLYV 188

  Fly   109 GNIPFGVTEEEMMEFFNQQMHLVGLAQAAGSPVLACQINLDKNFAFLEFRSIDETTQAMAFDGIN 173
            ||||||..||.|::||||||||.|||||.|:|:|.|||||||||||:|||||||||..|||||||
 Worm   189 GNIPFGCNEEAMLDFFNQQMHLCGLAQAPGNPILLCQINLDKNFAFIEFRSIDETTAGMAFDGIN 253

  Fly   174 LKGQSLKIRRPHDYQPMPGITDTPAIKPAVVSSGVISTVVPDSPHKIFIGGLPNYLNDDQVKELL 238
            ..||.||:|||.||||.....|..:..|       :||:|.||.:|||||||||||.:|||||||
 Worm   254 FMGQQLKVRRPRDYQPSQNTFDMNSRMP-------VSTIVVDSANKIFIGGLPNYLTEDQVKELL 311

  Fly   239 LSFGKLRAFNLVKDAATGLSKGYAFCEYVDLSITDQSIAGLNGMQLGDKKLIVQRASVGAK---- 299
            .|||.|:||:|..| :.|.||||||.||:|.::|||:||||||||||||:|:||.|....:
 Worm   312 CSFGPLKAFSLNVD-SQGNSKGYAFAEYLDPTLTDQAIAGLNGMQLGDKQLVVQLACANQQRHNT 375

  Fly   300 NAQNAANTTQSVMLQVPGLSNVVTSGPPTEVLCLLNMVTPDELRDEEEYEDILEDIKEECTKYGV 364
            |..|:|:.       :.|:.....:|..||:|||:||||.|||:.::|||:||||:::||:|||:
 Worm   376 NLPNSASA-------IAGIDLSQGAGRATEILCLMNMVTEDELKADDEYEEILEDVRDECSKYGI 433

  Fly   365 VRSVEIPRPIEGVEVPGCGKVFVEFNSVLDCQKAQQALTGRKFSDRVVVTSYFDPDKYHRREF 427
            |||:|||||.|...|||.|||||||.|..|||:||.|||||||::|.|||||:|.||||.|:|
 Worm   434 VRSLEIPRPYEDHPVPGVGKVFVEFASTSDCQRAQAALTGRKFANRTVVTSYYDVDKYHNRQF 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
U2af50	NP_001245708.1	U2AF_lg	<50..427	CDD:273727	233/390 (60%)
uaf-1	NP_001022967.1	U2AF_lg	118..496	CDD:273727	236/396 (60%)