DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sl and AT3G55940

DIOPT Version :9

Sequence 1:	NP_476726.2	Gene:	sl / 32601	FlyBaseID:	FBgn0003416	Length:	1236	Species:	Drosophila melanogaster
Sequence 2:	NP_191153.1	Gene:	AT3G55940 / 824760	AraportID:	AT3G55940	Length:	584	Species:	Arabidopsis thaliana

Alignment Length:	1014	Identity:	190/1014 - (18%)
Similarity:	316/1014 - (31%)	Gaps:	489/1014 - (48%)

- Green bases have known domain annotations that are detailed below.

  Fly   252 VRPAELK------------------QFL-ETEQRDVSASEISSAAIASFIRDFVQDVERDVQEPY 297
            |.|||:|                  :|| :.:::|.:..|.:        :|.|......:....
plant    22 VAPAEIKTLFDNYSDKGLMTTDLLLRFLIDVQKQDKATKEEA--------QDIVNASSSLLHRNG 78

  Fly   298 LTFPEFVDFLFSKQNDLWNSKYDQVFMDMNLPLSSYWIASSHNTYLTGDQFSSESSCEAYARALR 362
            |....|..:||:..|...:|.  :|..||:.|||.|:|.:.||:||||:|.||:.|......||:
plant    79 LHLDAFFKYLFAVTNSPLSSL--EVHQDMDAPLSHYFIYTGHNSYLTGNQLSSDCSELPIIEALK 141

  Fly   363 MGCRCIELDCW-NGPDNLPYIFHGHTITSKIKFMDVIKTIKDHAFTSSEYPVILSIEQNCSLEQQ 426
            .|.|.||||.| |..::...:.||.|:||.::.:..::.|::|||..|:|||::::|.:.:.:.|
plant   142 KGVRVIELDIWPNSDEDGIDVLHGRTLTSPVELIKCLRAIREHAFDVSDYPVVVTLEDHLTPKLQ 206

  Fly   427 RNMAQALIEVFGDMLLTQPCDRNEQHLPSPYQLRRKIILKHKKLPQFDDIANGISSTGSLGHRSS 491
            ..:|:.:.::||:||.|.|.....:..|||..|:::|::..|...::
plant   207 AKVAEMVTDIFGEMLFTPPSGECLKEFPSPAFLKKRIMISTKPPKEY------------------ 253

  Fly   492 LGGAGGGAHGENDGENVRKVFKEGLLYFKDPVDKSWNLYQFVLTHQELIYSSEINESRNGNSEDD 556

plant   254 ----------------------------------------------------------------- 253

  Fly   557 DFGLSSSCSLNSNMQQKQKDTSANDELHFGENWFHGKLEGGRKEADDLLKKYKHFGDGTFLVRES 621
                                .:|.|                    |||:||.:..||.....||.
plant   254 --------------------KAATD--------------------DDLVKKGRDLGDKEVWGREV 278

  Fly   622 ATFVGDYSLSFWRRNRPNHCRIKLKHENGSIKYYLVENFVFDSLYSLIVYYRKNMLRSSEFSIIL 686
            .:|:        ||:|    .:.....||.
plant   279 PSFI--------RRDR----SVDKNDSNGD----------------------------------- 296

  Fly   687 KEPVPQPKKHEDQEWFHPNTTKEQAEQGLYRLEIGSFLVRPSVQSINAFVISFTINRKIKHCRIM 751
                      :|.:
plant   297 ----------DDDD--------------------------------------------------- 300

  Fly   752 QEGRLYGIDTMNFESLVSLINYYTRNPLYRNVKLSHPVSQELLRQALAEAAQGDHSGGHDDNGAS 816
                                                                 |.....||:|
plant   301 -----------------------------------------------------DDDDDDDDDG-- 310

  Fly   817 NYMGSNLEENVTCKALYSYKANKPDELSFPKHAIITNVQRDNSMWWIGDYGGMIKKHLPANYVKV 881
                   ::.:        |.|.|.|.   ||.|.....:..        ||:
plant   311 -------DDKI--------KKNAPPEY---KHLIAIEAGKPK--------GGI------------ 337

  Fly   882 IDSTTEDYNSLNEEGTDGRTDSIEIFGAVASLFESNDPGIIFKLQIQTPTMQNPFVIGFDNQETA 946
                               |:.:::           ||..:.:|.:
plant   338 -------------------TECLKV-----------DPDKVRRLSL------------------- 353

  Fly   947 YEWIKAIQEAALIASQLASERRKKERTARVAKEMSDLIIYFRSVPFREHSWIFQEMSSFPETKAE 1011
                              ||.:.::.:.:.||::
plant   354 ------------------SEEQLEKASEKYAKQI------------------------------- 369

  Fly  1012 KQFFQQNTQLFLSYHRNQISRVYPKGQRLDSSNFNPMPFWNVGSQMIALNYQTGDKAMQLNQAKF 1076
            .:|.|:|           :.||||||.|:.|||:||:..|:.|:||:|.|.|...:::.:.|..|
plant   370 VRFTQRN-----------LLRVYPKGTRITSSNYNPLIAWSHGAQMVAFNMQGLGRSLWVMQGMF 423

  Fly  1077 RNNGQCGYILKPS-FMKSDS-FNPNNPLCDGLSEVKVSIRLIAARHLFRG------------GKS 1127
            |.||.||||.||. .:||:: |:|...|     .||.::|:.    ::.|            .:.
plant   424 RGNGGCGYIKKPDLLLKSNAVFDPEATL-----PVKTTLRVT----IYMGEGWYYDFPHTHFDRY 479

  Fly  1128 NNPQIV--VELIGASFDTGVKYRTKVNENGFNPVWNESCEFNVRNPQFAILRFEVQDEDMFAETH 1190
            :.|...  |.:.|...||.:| :||..|:.:.|.|:|..||.:..|:.|:||.||.:.||..:..
plant   480 SPPDFYTRVGIAGVPADTVMK-KTKTLEDNWIPAWDEVFEFPLTVPELALLRIEVHEYDMSEKDD 543

  Fly  1191 FIAQACYPLTCIRQGYRSVILRNKFSEELELSSLLINIK 1229
            |..|.|.|:..:|||.|:|.|||:...:.....||:.::
plant   544 FGGQICLPVWELRQGIRAVPLRNQDGVKCRSVKLLVRLE 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sl	NP_476726.2	PH_PLC_gamma	22..147	CDD:270168
		PI-PLCc_gamma	323..>470	CDD:176534	55/147 (37%)
		SH2_N-SH2_PLC_gamma_like	584..682	CDD:199829	15/97 (15%)
		SH2_C-SH2_PLC_gamma_like	696..796	CDD:198186	1/99 (1%)
		SH3_PLCgamma	828..880	CDD:212759	9/51 (18%)
		PLCYc	981..1091	CDD:128454	33/110 (30%)
		C2_PLC_like	1109..1215	CDD:175974	38/119 (32%)
AT3G55940	NP_191153.1	PLN02222	1..584	CDD:177868	190/1014 (19%)
		EF-hand_like	26..102	CDD:286375	14/85 (16%)
		PI-PLCc_GDPD_SF	102..426	CDD:301322	119/756 (16%)
		C2_PLC_like	454..583	CDD:175974	39/134 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	112	1.000	Domainoid score	I2055
eggNOG	1	0.900	-	-		E1_KOG0169
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1997
Inparanoid	1	1.050	235	1.000	Inparanoid score	I1114
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D368239at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2757
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X101
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.830