Protein Alignment sl and plcl2

DIOPT Version :9

• Sequence 1: NP_476726.2
• Gene: sl / 32601
• FlyBaseID: FBgn0003416
• Length: 1236
• Species: Drosophila melanogaster
• Sequence 2: XP_002667725.3
• Gene: plcl2 / 100334276
• -ID: -
• Length: 1097
• Species: Danio rerio
• Alignment Length: 1267
• Identity: 260/1267 - (20%)
• Similarity: 421/1267 - (33%)
• Gaps: 546/1267 - (43%)

  Fly     4 FSAM-SAPLLGEMEQTIGMLERGTIVTKLYGKQRRPDRRHLMLIRETRQLLWATVATQTPRTDYE 67
            ||:| :...:......|..:..|:.:.|:.... |...|:.:|..:.:.|.|.....::.:
Zfish    87 FSSMPTEKKISSASDCINSMVDGSELRKVRSNS-RVYHRYFLLDADMQSLRWEPSKKESDK---- 146

  Fly    68 GAIQLREIREIRVGKHSKEFRL------FADDCQRFESSKCFVILHGNHFKLKSFSVVALSEIEA 126
            ..|.::.|:|:|.||::..||.      .::||       .|.|::|.::  :|..:||.|...|
Zfish   147 AKIDVKSIKEVRTGKNTDTFRTNGISDQISEDC-------AFSIIYGENY--ESLDLVANSADVA 202

  Fly   127 DNWVRGLRYMV---KDTLGAPYPLQID---RWLRREYYQIENVNTHSAK-------ATEQSPAQV 178
            :.||.||||::   |.||......|.:   .||...:.:.:.:...|..       ..:.||.
Zfish   203 NIWVTGLRYLISYGKHTLNMIQSSQDNMRASWLGELFDEADAIGRKSISLCTAVQLIKKLSPG-- 265

  Fly   179 TIKDFKLFLAGVSCKMTTGKFME-HFTEDVRRKHDLKFDDFSRLYQKLLL-PNGFASVLSGSGVA 241
             :|:.|:.|          ||.| |.::| :...|:..::|..::..|.. |..:..::.
Zfish   266 -VKNVKIEL----------KFKELHKSKD-KSSSDVTKEEFIEVFHDLCTRPEIYFLLVQ----- 313

  Fly   242 NFPYSEDQQVVRPAELKQFLETEQRDVSASEISSAAIASFIRDFVQDVERDVQEPYLTFPEFVDF 306
               :|.:::.:...:|..|||.||.....||..|..:   |:.:....|..: :.:|:...|.::
Zfish   314 ---FSSNKEFLDTKDLMIFLEAEQGMAKVSEDISVEV---IQKYEPSKEGQL-KGWLSLDGFTNY 371

  Fly   307 LFSKQNDLWNSKYDQVFMDMNLPLSSYWIASSHNTYLTGDQFSSESSCEAYARALRMGCRCIELD 371
            |.|....:::.:...|..|||.|||.|:|.|||||||..|||...|....|.|||:||||.:|||
Zfish   372 LMSADCHIFDPEQKTVCQDMNQPLSHYYINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELD 436

  Fly   372 CWNGPDNLPYIFHGHTITSKIKFMDVIKTIKDHAFTSSEYPVILSIEQNCSLEQQRNMAQALIEV 436
            .|:||||.|.|:.|||:||:|.|.:||..|..:||.:||:|:.|.:|.:|||:||:.:.|.|.::
Zfish   437 VWDGPDNEPVIYTGHTMTSQIVFRNVIDIINKYAFAASEFPLFLCLENHCSLKQQKVIFQHLKKI 501

  Fly   437 FGDMLLTQPCDRNEQHLPSPYQLRRKIILKHKKLPQFDDIANGISSTGSLGHRSSLGGAGGGAHG 501
            .||.:.|.|.:..:.:||||..|:.||:||.||||
Zfish   502 LGDKVHTDPPNLEDNYLPSPLDLKGKILLKGKKLP------------------------------ 536

  Fly   502 ENDGENVRKVFKEGLLYFKDPVDKSWNLYQFVLTHQELIYSSEINESRNGNSEDDDFGLSSSCSL 566
                                                     |...|. .|...|:|.|...|..:
Zfish   537 -----------------------------------------SNCTEP-EGEVTDEDEGAEMSQRM 559

  Fly   567 NSNMQQKQKDTSANDELHFGENWFHGKLEGGRKEADDLLKKYKHFGDGTFLVRESATFVGDYSLS 631
            |:...::|
Zfish   560 NNEASEQQ--------------------------------------------------------- 567

  Fly   632 FWRRNRPNHCRIKLKHENGSIKYYLVENFVFDSLYSLIVYYRKNMLRSSEFSIILKEPVPQPKKH 696
                                                                     .|.||||.
Zfish   568 ---------------------------------------------------------VVVQPKKF 575

  Fly   697 EDQEWFHPNTTKEQAEQGLYRLEIGSFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRLYGIDT 761
            :
Zfish   576 Q---------------------------------------------------------------- 576

  Fly   762 MNFESLVSLINYYTRNPLYRNVKLSHPVSQELLRQALAEAAQGDHSGGHDDNGASNYMGSNLEEN 826
                                                                             
Zfish   577 ----------------------------------------------------------------- 576

  Fly   827 VTCKALYSYKANKPDELSFPKHAIITNVQRDNSMWWIGDYGGMIKKHLPANYVKVIDSTTEDYNS 891
                                                                             
Zfish   577 ----------------------------------------------------------------- 576

  Fly   892 LNEEGTDGRTDSIEIFGAVASLFESNDPGIIFKLQIQTPTMQNPFVIGFDNQETAYEWIKAIQEA 956
                                                                             
Zfish   577 ----------------------------------------------------------------- 576

  Fly   957 ALIASQLASERRKKERTARVAKEMSDLIIYFRSVPFREHSWIFQ-----EMSSFPETKAEKQFFQ 1016
                               ::|::|||:...:||.|::....||     |:.||.|..|.: ...
Zfish   577 -------------------LSKDLSDLVTLCKSVQFKDFQMAFQNQKHWELCSFNEVFASR-CAT 621

  Fly  1017 QNTQLFLSYHRNQISRVYPKGQRLDSSNFNPMPFWNVGSQMIALNYQTGDKAMQLNQAKFRNNGQ 1081
            .:...|::|::..::||||...|:||||.||..||..|.|::|:||||....|.||...||.||.
Zfish   622 DHPGDFVNYNKKFLARVYPSPMRIDSSNMNPQDFWKCGCQIVAMNYQTPGLMMDLNIGWFRQNGN 686

  Fly  1082 CGYILKPSFMKSD----SFNPNNPLCDGLSEVKVSIRLIAARHLFR----GGKSN--NPQIVVEL 1136
            |||:|:|:.|:..    |.|..:.: .|:|...:.|::|:..:|.:    |.|.:  :|.:.||:
Zfish   687 CGYVLRPAIMREQVSYFSANTKDSV-PGVSPQLLHIKIISGLNLPKPKGSGAKGDVVDPYVYVEI 750

  Fly  1137 IGASFDTGVKYRTK-VNENGFNPVWNESCEFNVRNPQFAILRFEVQDEDMFAETHFIAQACYPLT 1200
            .|...|. .:.||| |::||.||:::||.||.:..|:.|::||.|.|:|...: .||.|...|..
Zfish   751 HGIPADC-AEQRTKTVHQNGDNPIFDESFEFQINLPELAMVRFVVLDDDYIGD-EFIGQYTIPFE 813

  Fly  1201 CIRQGYRSVILRNKFSEELELSSLLINIKIAN 1232
            ||:.|:|.:.|::...|.|..:.:.:::.|.|
Zfish   814 CIQPGFRHIPLQSLTGEVLPHAWVFVHVAITN 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sl	NP_476726.2	PH_PLC_gamma	22..147	CDD:270168	34/133 (26%)
		PI-PLCc_gamma	323..>470	CDD:176534	75/146 (51%)
		SH2_N-SH2_PLC_gamma_like	584..682	CDD:199829	0/97 (0%)
		SH2_C-SH2_PLC_gamma_like	696..796	CDD:198186	0/99 (0%)
		SH3_PLCgamma	828..880	CDD:212759	0/51 (0%)
		PLCYc	981..1091	CDD:128454	47/114 (41%)
		C2_PLC_like	1109..1215	CDD:175974	38/112 (34%)
plcl2	XP_002667725.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D368239at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R928
SonicParanoid	1	1.000	-	-		X101
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950