Protein Alignment CalpC and capn2l

DIOPT Version :10

• Sequence 1: NP_573118.2
• Gene: CalpC / 32597
• FlyBaseID: FBgn0260450
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001003485.2
• Gene: capn2l / 445091
• ZFINID: ZDB-GENE-050417-341
• Length: 700
• Species: Danio rerio
• Alignment Length: 710
• Identity: 197/710 - (27%)
• Similarity: 352/710 - (49%)
• Gaps: 85/710 - (11%)

  Fly     5 YERILSDCRSKNVLWEDPDFPAVQSSVFYYQTPPFT-----FQWKRIMDLADSGSGAVAANSSAA 64
            ||.:..:|.....|::|..|.|..|::.:.:..|.:     .:|.|...|..:
Zfish    32 YEALKRECLESGRLFQDGMFEANVSALGFKELGPNSSKVRGVEWLRPKQLTSN------------ 84

  Fly    65 PVFLNESA-EFDVVPGKMGDRWLVSCLGLLSSLRNLFYRVVPADQTLASAH-GVFRFRLWWCGEW 127
            |.|::..| ..|:..|.:||.||::.:..|:..:::|.|||||.|:....: |:|.|:.|..|||
Zfish    85 PTFISGGATRTDICQGALGDCWLLAAIASLTLNQDVFARVVPAGQSFDGDYAGIFHFQFWQFGEW 149

  Fly   128 VEVLVDDRLPTINGRLAFMQPQASNCFWAALLEKAIAKLHGSYEALKYGTRSDGLTDLLGGV--V 190
            |:|::|||||...|.|.|:.....:.||:||||||.|||:|.||||..||.::|..|..||:  |
Zfish   150 VDVVIDDRLPARKGELLFVHSAEGSEFWSALLEKAYAKLNGCYEALSGGTTTEGFEDFTGGIAEV 214

  Fly   191 RQMPILSDNIRPQTLKELLTTTCIVTCLADKSATVAKKNLAERMPNGILVNVN-YRLSSLDKVKT 254
            .::|....|:. :|:::.|:...::.|..|    :...:.:|.:.:..||..: |.::..::|:
Zfish   215 HELPKAGPNLF-KTIQKALSWGSLLGCSID----ITSSSDSEAITSQKLVKGHAYSVTGAEEVE- 273

  Fly   255 LMGDSVQLVCLKDTFSSKPFGEKTHFLGDWSPMSKTWERVSQVERARLIRQLGPGEFWLSFCDFV 319
            ..||..:|:.:::     |:|: ..:.|.||..|..|.::|..:|.||..:...||||:||.||:
Zfish   274 YRGDLTKLIRIRN-----PWGQ-VEWTGPWSDGSSEWRQISDSDRERLSSKAEDGEFWMSFSDFM 332

  Fly   320 EIFSTMEVVYLDTETSNDEEMLKSRPLHWKMKMHQGQWKRGVTAGGCRNH-ESFHINPQLLISVQ 383
            ..:|.:|:..|..:...||.:.|     |.:....|.|:.|.|||||||: .||.:|||.||.::
Zfish   333 RHYSRVEICNLTPDALTDESVNK-----WALSKFDGNWRNGSTAGGCRNYPNSFWMNPQFLIKLE 392

  Fly   384 DEQD----------LVIALNQ-------HTAVEPKVIGFTMYTWDGEYM--LSECLQKDFFKNHV 429
            ::.|          .|:.|.|       ....:...|||.:|....|::  .:..|.::||..|.
Zfish   393 EQDDDPTDNEAGCSFVVGLIQKNRRKMRKVGEDMNTIGFAIYEVPDEFVGQRNVHLDRNFFVRHA 457

  Fly   430 SYLNSD-YGNTRHVSYHTHLEAGHYVLIPTTYEPAEEAHFTVRILGTGSFRLSCLETQTMILLDP 493
            |...|: :.|.|.|.....|..|.|:::|:|:||.::..|.||:       .|..:.:...|.||
Zfish   458 SAARSETFINLREVCSRFCLPPGEYLIVPSTFEPNKDGDFCVRV-------FSEKQAEFQELDDP 515

  Fly   494 FPA------LKSTDAERCGGPKVKSVCQYEPVYMQLADENKTINCFELHELLEACLP--NDYIKG 550
            ..:      :|..|.:          .::..::.|||..:..|:.|||.::|...:.  .|....
Zfish   516 VESKVAEIEIKEGDID----------SRFRNLFKQLAGADSEISAFELQKILNNVIAKRKDIKTD 570

  Fly   551 CANIDICRQVIALQDRSGSGRITFQQFKTFMVNLKSWQGVFKMYTKEKAGILRAERLRDALCDIG 615
            ..:::.||.::.|.|:.|:|::...:||.....::.:..|:....|:::|.:.:..:|:|:...|
Zfish   571 GFSLETCRNMVNLLDKDGTGKLGLLEFKILWTKIELFVDVYSKNDKDQSGTMSSMEMREAVEKAG 635

  Fly   616 FQLSTDIMNCLIQRYIRKDGTLRLSDFVSAVIHLTTAFNQFHLKNYGQVNVIEVHLHDWI 675
            |.|:..:...|:.||...:.|:...:||:.:|.|...|..|.:.:..:...:|:::.:|:
Zfish   636 FSLNNALHQILVARYSEPNLTIDFDNFVACLIRLECMFKAFKVLDKDKNGTVELNMMEWL 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CalpC	NP_573118.2	CysPc	7..329	CDD:238004	102/331 (31%)
		Calpain_III	346..483	CDD:238132	47/157 (30%)
		EFh_PEF	515..680	CDD:355382	37/163 (23%)
		EF-hand motif	515..543	CDD:320054	8/27 (30%)
		EF-hand motif	556..585	CDD:320054	8/28 (29%)
		EF-hand motif	586..615	CDD:320054	5/28 (18%)
		EF-hand motif	622..650	CDD:320054	7/27 (26%)
		EF-hand motif	652..680	CDD:320054	4/24 (17%)
capn2l	NP_001003485.2	None