DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CalpC and sri

DIOPT Version :9

Sequence 1:	NP_573118.2	Gene:	CalpC / 32597	FlyBaseID:	FBgn0260450	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	XP_005157918.1	Gene:	sri / 393344	ZFINID:	ZDB-GENE-040426-1356	Length:	190	Species:	Danio rerio

Alignment Length:	172	Identity:	43/172 - (25%)
Similarity:	81/172 - (47%)	Gaps:	11/172 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   515 QYEPVY---MQLADENKTINCFELHELLEACLPNDYIKG---CANIDICRQVIALQDRSGSGRIT 573
            |.:|:|   ..:|.::..|:.    |.|:|||......|   ..|::.||.:|::.||..|..:.
Zfish    23 QQDPLYGYFTAIAGQDGQISA----EELQACLTQANFSGGYRPFNLETCRLMISMLDRDMSYSMG 83

  Fly   574 FQQFKTFMVNLKSWQGVFKMYTKEKAGILRAERLRDALCDIGFQLSTDIMNCLIQRYIRKDGTLR 638
            |.:||.....|..|:..|....::.:|.:..:.:..|:..:|::||...||.:|:|| ...|.:.
Zfish    84 FNEFKELWAVLNGWKQHFMSIDRDMSGTVDPQEMNQAISSMGYRLSPQAMNSIIKRY-SSQGKIT 147

  Fly   639 LSDFVSAVIHLTTAFNQFHLKNYGQVNVIEVHLHDWIKSILS 680
            ..|:|:..:.|.:..:.|..::..|..:......|:|...:|
Zfish   148 FDDYVACCVKLRSLTDVFRKRDQAQQGMATFQYDDFIHCTMS 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CalpC	NP_573118.2	CysPc	7..329	CDD:238004
		Calpain_III	346..483	CDD:238132
		FRQ1	<567..648	CDD:227455	20/80 (25%)
sri	XP_005157918.1	EFh	37..92	CDD:298682	17/58 (29%)
		EFh	67..122	CDD:238008	14/54 (26%)
		EFh	101..153	CDD:238008	13/52 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910