DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CalpC and clpr-2

DIOPT Version :9

Sequence 1:	NP_573118.2	Gene:	CalpC / 32597	FlyBaseID:	FBgn0260450	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_001309563.1	Gene:	clpr-2 / 3565584	WormBaseID:	WBGene00023410	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	227	Identity:	53/227 - (23%)
Similarity:	83/227 - (36%)	Gaps:	41/227 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 HGVFRFRLWWCGEWVEVLVDDRLPTINGRLAFMQPQASNCFWAALLEKAIAKLHGSYEALKYGTR 178
            ||:.:.||...|||..:.:|..:|:.:.......|......||||::||.|||.|||..|..|..
Worm     3 HGIAQIRLLINGEWKVIKIDFHVPSSSASYEIFTPMVRKQAWAALIQKAFAKLGGSYAKLHGGFA 67

  Fly   179 SDGLTDLLGGVVRQM---PILSDN-----IRPQTLKELLTTTCIVTC-LADKSATVAKKNLAERM 234
            ......|.|......   .:.|||     |......:.|.|.|...| ...:...:..||
Worm    68 DIAFLQLTGSFTSTYYLNKLSSDNDIWDFILSMQKSKFLVTACSTYCEEGSEEWDIFLKN----- 127

  Fly   235 PNGILVNVNYRLSSLDKVKTLMGDSVQLVCLKDTFSSKPFGEKTHFLGDWSPMSKTWERVSQVER 299
                .::.|:..|.||   |.:.:..:||.:         |..|:.|.|....:..|..:.:.:.
Worm   128 ----QISPNHGYSILD---TKIHEGHRLVLI---------GNFTYSLPDQGTGTLKWGHLPRFDE 176

  Fly   300 ARLIRQLGPGEFWLSFCDFVEIFSTMEVVYLD 331
            ..|...:           |..:.||..:.::|
Worm   177 KCLCGNI-----------FDYVLSTTSIHWVD 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CalpC	NP_573118.2	CysPc	7..329	CDD:238004	52/223 (23%)
		Calpain_III	346..483	CDD:238132
		FRQ1	<567..648	CDD:227455
clpr-2	NP_001309563.1	CysPc	<2..212	CDD:381776	53/227 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704215at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820