DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CalpC and Gca

DIOPT Version :9

Sequence 1:	NP_573118.2	Gene:	CalpC / 32597	FlyBaseID:	FBgn0260450	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_001099953.1	Gene:	Gca / 295647	RGDID:	1306589	Length:	220	Species:	Rattus norvegicus

Alignment Length:	147	Identity:	35/147 - (23%)
Similarity:	76/147 - (51%)	Gaps:	4/147 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   537 ELLEACLPNDYIKGC---ANIDICRQVIALQDRSGSGRITFQQFKTFMVNLKSWQGVFKMYTKEK 598
            |.|:.||....|.|.   .:::.||.:||:.||..:|::.|.:||.....|.:|:..|....:::
  Rat    74 EELQRCLTQSGISGSYAPFSLETCRIMIAMLDRDYTGKMGFNEFKELWAALNAWKQNFMSIDQDQ 138

  Fly   599 AGILRAERLRDALCDIGFQLSTDIMNCLIQRYIRKDGTLRLSDFVSAVIHLTTAFNQFHLKNYGQ 663
            :|.:....|..|:..:|::||...:..:::|| .|:|.:...|:|:..:.|....:.|..:::.|
  Rat   139 SGTVEHHELSQAIALMGYRLSPQTLAAIVRRY-SKNGRIFFDDYVACCVKLRALTDFFRRRDHLQ 202

  Fly   664 VNVIEVHLHDWIKSILS 680
            ..::.....|:::..::
  Rat   203 QGIVNFMYEDFLQGTMT 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CalpC	NP_573118.2	CysPc	7..329	CDD:238004
		Calpain_III	346..483	CDD:238132
		FRQ1	<567..648	CDD:227455	19/80 (24%)
Gca	NP_001099953.1	Bindin	1..>78	CDD:251078	2/3 (67%)
		EFh	67..122	CDD:238008	16/47 (34%)
		EF-hand_7	67..120	CDD:290234	16/45 (36%)
		EFh	97..152	CDD:298682	16/54 (30%)
		EF-hand_7	128..183	CDD:290234	12/55 (22%)
		EFh	131..183	CDD:298682	12/52 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910