DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CalpC and clpr-1

DIOPT Version :9

Sequence 1:	NP_573118.2	Gene:	CalpC / 32597	FlyBaseID:	FBgn0260450	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_493397.3	Gene:	clpr-1 / 189180	WormBaseID:	WBGene00012233	Length:	252	Species:	Caenorhabditis elegans

Alignment Length:	232	Identity:	59/232 - (25%)
Similarity:	81/232 - (34%)	Gaps:	66/232 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 GEWVEVLVDDRLPTINGRLAFMQPQASNCF-----------WAALLEKAIAKLHGSYEALKYGTR 178
            |||..:.:|           |..||.||.|           |.|.:||..||:..|||.|..|..
Worm    33 GEWKVLKID-----------FHLPQKSNSFERYAYMVKKQIWVAFIEKGFAKIRKSYEKLSGGVA 86

  Fly   179 SDGLTDLLGGVV-------------RQMPILSDNIRPQTLKELLTTTCIVTCLADKSATVAKKNL 230
            ...|..|.|.:.             |....:.:|...:.:..:.|.|     :.::|   .||.|
Worm    87 GIALQQLTGAMTFSVFMEKFNNDENRVWEFIQENRNSKFILTVSTPT-----IEEES---EKKQL 143

  Fly   231 AERMPNGILVNVNYRLSSLDKVKTLMGDSVQLVCLKDTFSSKPFGEKTHFLGDWSPMS-KTWERV 294
            .|..  ||.....|  |.|| .:..||..:.|:.     .|.|||:         |.| :.|..:
Worm   144 LEEY--GIRDCHEY--SVLD-AQVYMGHRLILLA-----GSGPFGK---------PKSVRRWGHL 189

  Fly   295 SQVERAR---LIRQLGPGEFWLSFCDFVEIFSTMEVV 328
            ...:..|   ....||..||...:.|..|:|...|.|
Worm   190 PSYKEIREDWCAVDLGFSEFGTFWIDMSELFQYFEYV 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CalpC	NP_573118.2	CysPc	7..329	CDD:238004	59/232 (25%)
		Calpain_III	346..483	CDD:238132
		FRQ1	<567..648	CDD:227455
clpr-1	NP_493397.3	CysPc	<28..229	CDD:381776	59/232 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810