Protein Alignment CalpC and Capn5

DIOPT Version :9

• Sequence 1: NP_573118.2
• Gene: CalpC / 32597
• FlyBaseID: FBgn0260450
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_604456.2
• Gene: Capn5 / 171495
• RGDID: 620084
• Length: 640
• Species: Rattus norvegicus
• Alignment Length: 647
• Identity: 176/647 - (27%)
• Similarity: 284/647 - (43%)
• Gaps: 125/647 - (19%)

  Fly     5 YERILSDCRSKNVLWEDPDFPAVQSSVFYYQTPPFTFQWKRIMDLADSGSGAVAANSSAAPVFLN 69
            |..:...|..:.||:|||.|||...|::|..||..|.:|||..|:.|.           ..:|::
  Rat    13 YSALKRACLRRKVLFEDPHFPATDDSLYYKGTPGPTVRWKRPKDICDD-----------PRLFVD 66

  Fly    70 ESAEFDVVPGKMGDRWLVSCLGLLSSLRNLFYRVVP-------ADQTLASAHGVFRFRLWWCGEW 127
            ..:..|:..|::|:.|.|:....|:|..:|:.:|:|       ..:...|..|:|.|..|..|||
  Rat    67 GISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWNPEKPDSYAGIFHFNFWRFGEW 131

  Fly   128 VEVLVDDRLPTINGRLAFMQPQASNCFWAALLEKAIAKLHGSYEALKYGTRSDGLTDLLGGVVRQ 192
            |:|:|||||||:|.:|.:....:.|.||.||:|||.|||.|.|:||..|..:|.|.|..|||...
  Rat   132 VDVVVDDRLPTVNNQLIYCHSNSKNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEP 196

  Fly   193 MPILSDNI------RPQTLKELLTTTCIVTCLADKSATVAKKNLAERMPNGILVNVNYRLSSLDK 251
            :.:...::      |.|..:.:|........::.....:...::..|:..|::....|.::.:.|
  Rat   197 IDLTEGDLATDEAKRSQLFERVLKVHSRGGLISASIKAMTAADMETRLACGLVKGHAYAVTDVRK 261

  Fly   252 VKTLMG-------DSVQLVCLKDTFSSKPFGEKTHFLGDWSPMSKTWERVSQVERARL-IRQLGP 308
            |:...|       :.:.::.|::     |:||: .:.|.||..|:.|::||:.||.:: :.....
  Rat   262 VRLGHGLLAFFKSEKLDMIRLRN-----PWGER-EWTGPWSDTSEEWQKVSKSEREKMGVTVQDD 320

  Fly   309 GEFWLSFCDFVEIFSTMEVVYLDTETSNDEEMLKSRPLH---------WKMKMHQGQWKRGV--- 361
            ||||::|.|....|:               :::|.|.::         |:....:|.|.|..
  Rat   321 GEFWMTFEDMCRYFT---------------DIIKCRLINTSYLSIHKTWEEARLRGAWTRHEDPQ 370

  Fly   362 --TAGGCRNH-ESFHINPQLLISV-QDEQDLVIALNQH----TAVEPK----VIGFTMYTWD--G 412
              .:|||.|| ::|..|||.:..| :.|.:::|.:.|.    |..|.|    .|||.:|..:  .
  Rat   371 QNRSGGCINHKDTFFQNPQYIFEVKKPEDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENR 435

  Fly   413 EYMLSECLQKDFFKNHVSYLNSDYGNTRHVSYHTHLEAGHYVLIPTTYEPAEEAHFTVRIL---- 473
            :|.:.....|        ..:|.|.|:|.|...|.|..|.||:||||:||.....|.:|:.
  Rat   436 QYRMHSLQHK--------AASSIYINSRSVFLRTELPEGRYVIIPTTFEPGHTGEFLLRVFTDVP 492

  Fly   474 -GTGSFRL-----SCLE---------TQTMILLDPFPALK--STDAE-----RCGGPKVKSVCQ- 515
             .....||     :|..         ||..:|  ....||  ||.|.     :|.|.||:|..|
  Rat   493 SNCRELRLDEPPRTCWSSLCGYPQQVTQVHVL--GAAGLKDSSTGANSYVIIKCEGEKVRSAVQR 555

  Fly   516 ------YEP---VYMQLADENKTINCFELHELLEACLPNDYIKGCANIDICRQVIALQDRSG 568
                  |..   .|.:...:..|:..:....|.:..|...::|...:.......:.||||||
  Rat   556 GTSTPEYNVKGIFYRKKLSQPITVQVWNHRVLKDEFLGQVHLKTAPDDLQDLHSLHLQDRSG 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CalpC	NP_573118.2	CysPc	7..329	CDD:238004	100/342 (29%)
		Calpain_III	346..483	CDD:238132	46/172 (27%)
		FRQ1	<567..648	CDD:227455	2/2 (100%)
Capn5	NP_604456.2	Peptidase_C2	27..341	CDD:279042	98/345 (28%)
		Domain III	344..496		44/159 (28%)
		Calpain_III	354..493	CDD:279416	44/146 (30%)
		C2_Calpain	515..638	CDD:176011	26/105 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704215at2759
OrthoFinder	1	1.000	-	-		FOG0000071
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920