Protein Alignment CalpC and Capn5

DIOPT Version :9

• Sequence 1: NP_573118.2
• Gene: CalpC / 32597
• FlyBaseID: FBgn0260450
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_006507338.1
• Gene: Capn5 / 12337
• MGIID: 1100859
• Length: 653
• Species: Mus musculus
• Alignment Length: 594
• Identity: 158/594 - (26%)
• Similarity: 258/594 - (43%)
• Gaps: 135/594 - (22%)

  Fly     5 YERILSDCRSKNVLWEDPDFPAVQSSVFYYQTPPFTFQWKRIMDLADSGSGAVAANSSAAPVFLN 69
            |..:...|..|.||:|||.|||...|::|..||..|.:|||..|:.|.           ..:|::
Mouse    26 YSALKRACLRKKVLFEDPLFPATDDSLYYKGTPGPTVRWKRPKDICDD-----------PRLFVD 79

  Fly    70 ESAEFDVVPGKMGDRWLVSCLGLLSSLRNLFYRVVP-------ADQTLASAHGVFRFRLWWCGEW 127
            ..:..|:..|::|:.|.|:....|:|..:|:.:|:|       ..:...|..|:|.|..|..|||
Mouse    80 GISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWNPEKPDSYAGIFHFNFWRFGEW 144

  Fly   128 VEVLVDDRLPTINGRLAFMQPQASNCFWAALLEKAIAKLHGSYEALKYGTRSDGLTDLLGGVVRQ 192
            |:|:|||||||:|.:|.:....:.|.||.||:|||.|||.|.|:||..|..:|.|.|..|||...
Mouse   145 VDVIVDDRLPTVNNQLIYCHSNSKNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEP 209

  Fly   193 MPILSDNI------RPQTLKELLTTTCIVTCLADKSATVAKKNLAERMPNGILVNVNYRLSSLDK 251
            :.:...::      |.|..:.:|........::.....|...::..|:..|::....|.::.:.|
Mouse   210 IDLTEGDLATDEAKRNQLFERVLKVHSRGGLISASIKAVTAADMEARLACGLVKGHAYAVTDVRK 274

  Fly   252 VKTLMG-------DSVQLVCLKDTFSSKPFGEKTHFLGDWSPMSKTWERVSQVERARL-IRQLGP 308
            |:...|       :.:.::.|::     |:||: .:.|.||..|:.|::||:.||.:: :.....
Mouse   275 VRLGHGLLAFFKSEKLDMIRLRN-----PWGER-EWTGPWSDTSEEWQKVSKSEREKMGVTVQDD 333

  Fly   309 GEFWLSFCDFVEIFSTMEVVYLDTETSNDEEMLKSRPLH---------WKMKMHQGQWKRGV--- 361
            ||||::|.|....|:               :::|.|.::         |:.....|.|.|..
Mouse   334 GEFWMTFEDMCRYFT---------------DIIKCRLINTSYLSIHKTWEEARLHGAWTRHEDPQ 383

  Fly   362 --TAGGCRNH-ESFHINPQLLISV-QDEQDLVIALNQH----TAVEPK----VIGFTMYTWD--G 412
              .:|||.|| ::|..|||.:..| :.|.:::|::.|.    |..|.|    .|||.:|..:  .
Mouse   384 QNRSGGCINHKDTFFQNPQYVFEVKKPEDEVLISIQQRPKRSTRREGKGENLAIGFDIYKVEENR 448

  Fly   413 EYMLSECLQKDFFKNHVSYLNSDYGNTRHVSYHTHLEAGHYVLIPTTYEPAEEAHFTVR------ 471
            :|.:.....|        ..:|.|.|:|.|...|.|..|.||:||||:||.....|.:|
Mouse   449 QYRMHSLQHK--------AASSIYINSRSVFLRTELPEGRYVIIPTTFEPGHTGEFLLRVFTDVP 505

  Fly   472 ------------------------------ILGTGSFRLSCLETQTMILLDPFPALKSTDAERCG 506
                                          :||....:.|.....:.:::            :|.
Mouse   506 SNCRELRLDEPPRTCWSSLCGYPQQVAQVHVLGAAGLKDSPTGANSYVII------------KCE 558

  Fly   507 GPKVKSVCQ 515
            |.||:|..|
Mouse   559 GEKVRSAVQ 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CalpC	NP_573118.2	CysPc	7..329	CDD:238004	102/342 (30%)
		Calpain_III	346..483	CDD:238132	47/198 (24%)
		FRQ1	<567..648	CDD:227455
Capn5	XP_006507338.1	Peptidase_C2	40..354	CDD:366222	99/345 (29%)
		Calpain_III	365..511	CDD:238132	44/153 (29%)
		C2_Calpain	528..651	CDD:176011	9/52 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704215at2759
OrthoFinder	1	1.000	-	-		FOG0000071
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820