Protein Alignment CalpC and capn6

DIOPT Version :9

• Sequence 1: NP_573118.2
• Gene: CalpC / 32597
• FlyBaseID: FBgn0260450
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_031747775.1
• Gene: capn6 / 100494450
• XenbaseID: XB-GENE-992087
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 635
• Identity: 168/635 - (26%)
• Similarity: 275/635 - (43%)
• Gaps: 115/635 - (18%)

  Fly     5 YERILSDCRSKNVLWEDPDFPAVQSSVFYYQTPPFTFQWKRIMDLADSGSGAVAANSSAAPVFLN 69
            |..:..:|.....|:|||:|||...|:||.:.|....:|||..:|.:.           ..:|::
 Frog    13 YHELKKECIKNGKLFEDPEFPASDESLFYSKAPDLRIEWKRPKELCED-----------PHLFVD 66

  Fly    70 ESAEFDVVPGKMGDRWLVSCLGLLSSLRNLFYRVV----PADQTLASAH---GVFRFRLWWCGEW 127
            ..:..|:..|::|:.|.|:....|:..:.|:.:|:    ..:......|   |:|.|:.|..|:|
 Frog    67 GISSHDLHQGRLGNCWFVAACSCLALKKALWTKVISNWKKQEWDPKRPHRYAGIFHFKFWCLGDW 131

  Fly   128 VEVLVDDRLPTINGRLAFMQPQASNCFWAALLEKAIAKLHGSYEALKYGTRSDGLTDLLGGVVRQ 192
            |:|::|||||:::|.|.:......|.||:||||||.|||.||||||..|..:|.:.|..|.|...
 Frog   132 VDVVIDDRLPSVDGNLVYCHSNVKNEFWSALLEKAYAKLAGSYEALDGGNTADAIVDFTGAVTES 196

  Fly   193 MPILSDNIRP---------QTLKELLTTTCIVTCLADKSATVAKKNLAERMPNGILVNVNYRLSS 248
            ..:...:.|.         |.|.::.....:::|..   ..|:..::......|::....|.:::
 Frog   197 FELDKGDYRTSLMEQTKLFQELLKVYRAGGLISCYI---KPVSSNDMEAVTSYGLVKGHAYSVTA 258

  Fly   249 LDKVKT-----LMGDSVQLVCLKDTFSSKPFGEKTHFLGDWSPMSKTWERVSQVERARL-IRQLG 307
            :.|:..     ..|:|.:|..::   ...|:| |..:.|.||..|:.|.:||:.|:|.| :....
 Frog   259 IKKMPVGQRILCFGNSNKLFMIR---MRNPWG-KREWKGAWSDESEEWNKVSRSEKATLGLTVAD 319

  Fly   308 PGEFWLSFCDFVEIFSTMEVV------YLDTETSNDEEMLKSRPLHWKMKMHQGQWKRGV----- 361
            .||||::|.|:...|:..:|.      ||....:            ||.:...|.|.:..
 Frog   320 DGEFWMTFEDWCLSFTHADVCRILNTSYLSCYKT------------WKQEEVHGAWSKNTDPLLN 372

  Fly   362 TAGGCRNHESFHINPQLLISVQDEQD-LVIALNQ-HTAVEPK-------VIGFTMYTWDGEYMLS 417
            .:|||.|..:|..|||.:..|:.::| ::|:|.| ...:..|       :|||.::..:
 Frog   373 RSGGCFNETTFFQNPQYIFEVRKKEDEVLISLQQKDQRIHKKDGKGNNFIIGFEIFKVE------ 431

  Fly   418 ECLQKDFFKNHVS----YLNSDYGNTRHVSYHTHLEAGHYVLIPTTYEPAEEAHFTVRILGTGSF 478
              |.:::..:.:|    .|.|.|.|.|.:.....|..|.||:||||:.|...:.|.:|:....|.
 Frog   432 --LNREYRIHMISGQEKTLRSSYINLRAIFLRKVLTHGRYVIIPTTFHPGISSSFILRLFTDESS 494

  Fly   479 RLSCLETQTMILLDPFPALKSTDAERCGGP-KVKSVC------------QYEP-VYMQLADENKT 529
            |.      ..:|||. |.: |..:..||.| :|..|.            ..|| :|:.:..|.:|
 Frog   495 RF------RELLLDK-PKV-SCWSLLCGYPQRVTQVLVRHVEGVERQGQMQEPNLYIMIKGEKQT 551

  Fly   530 INCFELHELLEACLPNDYIKGCANID--ICRQVIALQDRSGSGRITFQQF 577
            |......:...|......|....||.  ||.||       ...||...||
 Frog   552 IRSLVYKKTSTAKFDIQAIFFRKNISEPICIQV-------WDSRIICDQF 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CalpC	NP_573118.2	CysPc	7..329	CDD:238004	96/349 (28%)
		Calpain_III	346..483	CDD:238132	41/154 (27%)
		FRQ1	<567..648	CDD:227455	4/11 (36%)
capn6	XP_031747775.1	Peptidase_C2	27..341	CDD:395523	94/331 (28%)
		Calpain_III	361..489	CDD:395848	37/135 (27%)
		C2_Calpain	516..640	CDD:176011	21/86 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704215at2759
OrthoFinder	1	1.000	-	-		FOG0000071
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920