DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CalpC and gca

DIOPT Version :9

Sequence 1:	NP_573118.2	Gene:	CalpC / 32597	FlyBaseID:	FBgn0260450	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_001119547.1	Gene:	gca / 100125139	XenbaseID:	XB-GENE-983090	Length:	203	Species:	Xenopus tropicalis

Alignment Length:	137	Identity:	38/137 - (27%)
Similarity:	72/137 - (52%)	Gaps:	7/137 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   537 ELLEACLPNDYIKGC---ANIDICRQVIALQDRSGSGRITFQQFKTFMVNLKSWQGVFKMYTKEK 598
            |.|:.||....|:|.   .:::.||.:||:.||..:|::.|.:||.....|.:|:..|..:.:::
Frog    57 EELQRCLTQAGIQGTYTPFSLETCRVLIAMLDRDFTGKMGFSEFKEVWGALSAWKQNFCTFDQDR 121

  Fly   599 AGILRAERLRDALCDIGFQLSTDIMNCLIQRYIRKDGTLRLSDFVSAVIH---LTTAFNQFHLKN 660
            :|.:....|..|:..:|::||...::.:::|| .|:|.:...|:|:..:.   ||..|.:.....
Frog   122 SGTVEPHELNQAIFAMGYRLSPPTLSTIVKRY-SKNGRIYFDDYVACCVKLRALTDVFRRRDGMQ 185

  Fly   661 YGQVNVI 667
            .|.||.|
Frog   186 QGFVNFI 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CalpC	NP_573118.2	CysPc	7..329	CDD:238004
		Calpain_III	346..483	CDD:238132
		FRQ1	<567..648	CDD:227455	19/80 (24%)
gca	NP_001119547.1	EFh_PEF_grancalcin	39..203	CDD:320061	38/137 (28%)
		EF-hand motif	39..67	CDD:320061	4/9 (44%)
		EF-hand motif	79..108	CDD:320061	10/28 (36%)
		EF-hand motif	109..139	CDD:320061	5/29 (17%)
		EF-hand motif	145..172	CDD:320061	6/27 (22%)
		EF-hand motif	173..203	CDD:320061	7/20 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910