DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp1 and CPR8

DIOPT Version :9

Sequence 1:	NP_523366.2	Gene:	Cyp1 / 32595	FlyBaseID:	FBgn0004432	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_014425.3	Gene:	CPR8 / 855762	SGDID:	S000005311	Length:	308	Species:	Saccharomyces cerevisiae

Alignment Length:	170	Identity:	45/170 - (26%)
Similarity:	75/170 - (44%)	Gaps:	31/170 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 VFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSI---------------FHR 118
            ||.|..:..|....|.::|...:||||...|   |.      |..|:               |.:
Yeast    55 VFTDPESSEEAGRLITIDLYGTMVPKTVMTF---CQ------YVDSVKDRLASRHSYSPERDFDK 110

  Fly   119 VIPNFMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTA 183
            ::||...:|...:: :......:...|.|:||..|.|...|.:||..   :..|.:|.|.|.:|.
Yeast   111 ILPNGAIEGSSVSS-SSIEETEMLAPKLPEENHSLIHDRPGRVSMIK---DDKGLKFIIETSETP 171

  Fly   184 WLDNKHVVFGEVVEGL-DVVKKIESYGS-QSGKTSKKIIV 221
             |:.:.||||:|..|| |::.|:.:..: ::||..:.|.:
Yeast   172 -LEGESVVFGQVTAGLKDLMDKLANVKTDENGKPEQPITI 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp1	NP_523366.2	cyclophilin_ABH_like	67..225	CDD:238907	45/170 (26%)
CPR8	NP_014425.3	cyclophilin	65..210	CDD:412213	41/158 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900