DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp1 and Ppig

DIOPT Version :9

Sequence 1:	NP_523366.2	Gene:	Cyp1 / 32595	FlyBaseID:	FBgn0004432	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_113981.2	Gene:	Ppig / 83624	RGDID:	620315	Length:	752	Species:	Rattus norvegicus

Alignment Length:	187	Identity:	92/187 - (49%)
Similarity:	119/187 - (63%)	Gaps:	20/187 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 GIQIVREYSKASKMSTLPRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFG---- 110
            ||::.|           ||.|||:..:|:|.||:|.||.|||.|||.||||.|||||||.|
  Rat     2 GIKVQR-----------PRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQ 55

  Fly   111 ----YKGSIFHRVIPNFMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTN 171
                ||..:||||:.:||.|||||:..||.||:||||..|.||:|.:||....:|||||.|.:||
  Rat    56 KPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTN 120

  Fly   172 GSQFFICTVKTAWLDNKHVVFGEVVEGLDVVKKIESYGSQ-SGKTSKKIIVANSGSL 227
            ||||||.|..|..||..|||||:|:.|.:||::||:..:. :.|...::.:.:.|.|
  Rat   121 GSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGEL 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp1	NP_523366.2	cyclophilin_ABH_like	67..225	CDD:238907	87/166 (52%)
Ppig	NP_113981.2	cyclophilin	8..175	CDD:412213	87/166 (52%)
Ppig	NP_113981.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	182..752
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820