DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp1 and Cwc27

DIOPT Version :9

Sequence 1:	NP_523366.2	Gene:	Cyp1 / 32595	FlyBaseID:	FBgn0004432	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_001347023.1	Gene:	Cwc27 / 67285	MGIID:	1914535	Length:	472	Species:	Mus musculus

Alignment Length:	129	Identity:	58/129 - (44%)
Similarity:	74/129 - (57%)	Gaps:	10/129 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 RVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPNFMCQGGDFTN 132
            :|....||     |.|.:||.|...||...||..||....   |..:|||||:|.|:.||||.|.
Mouse    14 KVLLKTTA-----GDIDIELWSKEAPKACRNFIQLCLEAY---YDNTIFHRVVPGFIVQGGDPTG 70

  Fly   133 HNGTGGKSIYGNKFPDE-NFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKHVVFGEV 195
             .||||:||||..|.|| :..|:....|:::|||||.:.||||||....:...|:|||.:||:|
Mouse    71 -TGTGGESIYGAPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKV 133

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp1	NP_523366.2	cyclophilin_ABH_like	67..225	CDD:238907	58/129 (45%)
Cwc27	NP_001347023.1	cyclophilin_CeCYP16-like	8..178	CDD:238906	58/129 (45%)
Cwc27	NP_001347023.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	431..472
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900