DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp1 and ppifb

DIOPT Version :9

Sequence 1:	NP_523366.2	Gene:	Cyp1 / 32595	FlyBaseID:	FBgn0004432	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_001032199.2	Gene:	ppifb / 641328	ZFINID:	ZDB-GENE-051030-126	Length:	192	Species:	Danio rerio

Alignment Length:	201	Identity:	132/201 - (65%)
Similarity:	153/201 - (76%)	Gaps:	12/201 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 ILANKSITLASSACSVNRGQLQFGIQIVREYSKASKMSTLPRVFFDMTADNEPLGRIVMELRSDV 91
            ||.|:     ...|||       .....|.||...:.:..|.||||:.|||:||||:..||.:||
Zfish     3 ILGNR-----LKLCSV-------AFTAARLYSTGVQANNNPVVFFDIAADNQPLGRVTFELNADV 55

  Fly    92 VPKTAENFRALCTGEKGFGYKGSIFHRVIPNFMCQGGDFTNHNGTGGKSIYGNKFPDENFELKHT 156
            |||||||||||||||.||||||||||||||.|||||||||||||||||||||.:||||||:||||
Zfish    56 VPKTAENFRALCTGEHGFGYKGSIFHRVIPQFMCQGGDFTNHNGTGGKSIYGPRFPDENFKLKHT 120

  Fly   157 GSGILSMANAGANTNGSQFFICTVKTAWLDNKHVVFGEVVEGLDVVKKIESYGSQSGKTSKKIIV 221
            |.|||||||||.|||||||||||.||.|||.:|||||.|.||:|||:|:|:.||:||:|:::|.:
Zfish   121 GPGILSMANAGVNTNGSQFFICTAKTEWLDGRHVVFGSVKEGMDVVRKVEALGSRSGRTAQRISI 185

  Fly   222 ANSGSL 227
            .:.|.|
Zfish   186 TDCGEL 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp1	NP_523366.2	cyclophilin_ABH_like	67..225	CDD:238907	121/157 (77%)
ppifb	NP_001032199.2	cyclophilin_ABH_like	31..189	CDD:238907	121/157 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	261	1.000	Domainoid score	I1920
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38696
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53630
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100528
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R284
SonicParanoid	1	1.000	-	-		X209
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.720