DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp1 and Ppie

DIOPT Version :9

Sequence 1:	NP_523366.2	Gene:	Cyp1 / 32595	FlyBaseID:	FBgn0004432	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_062362.1	Gene:	Ppie / 56031	MGIID:	1917118	Length:	301	Species:	Mus musculus

Alignment Length:	166	Identity:	114/166 - (68%)
Similarity:	134/166 - (80%)	Gaps:	0/166 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 ASKMSTLPRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPNFM 124
            |.|..:.|:|:.|:...|:|.|||.|.|||||||.||||||.|||.|||||:|||.|||:||.||
Mouse   133 AKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSFHRIIPQFM 197

  Fly   125 CQGGDFTNHNGTGGKSIYGNKFPDENFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKH 189
            |||||||||||||||||||.||.||||.|||||.|:|||||:|.||||||||:...||.|||.||
Mouse   198 CQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKH 262

  Fly   190 VVFGEVVEGLDVVKKIESYGSQSGKTSKKIIVANSG 225
            ||||||.|||||:::||:.||:.||..:|:::|:.|
Mouse   263 VVFGEVTEGLDVLRQIEAQGSKDGKPKQKVMIADCG 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp1	NP_523366.2	cyclophilin_ABH_like	67..225	CDD:238907	111/157 (71%)
Ppie	NP_062362.1	RRM	<5..194	CDD:223796	38/60 (63%)
		RRM_PPIE	8..80	CDD:240793
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	110..141		2/7 (29%)
		cyclophilin_ABH_like	140..298	CDD:238907	111/157 (71%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53630
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820