DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp1 and ppil4

DIOPT Version :9

Sequence 1:	NP_523366.2	Gene:	Cyp1 / 32595	FlyBaseID:	FBgn0004432	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_001121802.1	Gene:	ppil4 / 554886	ZFINID:	ZDB-GENE-030131-6251	Length:	454	Species:	Danio rerio

Alignment Length:	135	Identity:	54/135 - (40%)
Similarity:	76/135 - (56%)	Gaps:	13/135 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 LGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPNFMCQGGDFTNHNGTGGKSIYGN 144
            ||.||::|.::..||.:.||..||   |...|...:.|.|..:|:.|.||.|. .|.||:|::..
Zfish     9 LGDIVIDLYTEERPKASLNFLKLC---KIKYYNYCLIHNVQRDFIIQTGDPTG-TGRGGESVFCK 69

  Fly   145 KFPDEN--FE------LKHTGSGILSMANAGANTNGSQFFICTVKTA-WLDNKHVVFGEVVEGLD 200
            .:.|:.  ||      :||...|.:||.|.|::.:||||.|.|.:.. :||..|.|||||.||:|
Zfish    70 LYGDQARFFESEKMPRIKHRKKGTVSMVNNGSDQHGSQFLITTGENVDYLDGVHTVFGEVTEGMD 134

  Fly   201 VVKKI 205
            |:.||
Zfish   135 VLAKI 139

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp1	NP_523366.2	cyclophilin_ABH_like	67..225	CDD:238907	54/135 (40%)
ppil4	NP_001121802.1	cyclophilin_RRM	4..169	CDD:238902	54/135 (40%)
		RRM	172..>320	CDD:223796
		RRM_PPIL4	237..319	CDD:240681
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900