Protein Alignment Cyp1 and PPIL1

DIOPT Version :10

• Sequence 1: NP_523366.2
• Gene: Cyp1 / 32595
• FlyBaseID: FBgn0004432
• Length: 227
• Species: Drosophila melanogaster
• Sequence 2: NP_057143.1
• Gene: PPIL1 / 51645
• HGNCID: 9260
• Length: 166
• Species: Homo sapiens
• Alignment Length: 140
• Identity: 67/140 - (47%)
• Similarity: 91/140 - (65%)
• Gaps: 10/140 - (7%)

  Fly    67 PRVFFDMTADNEPLGRIVMELRSDVVPKTAENFRALCTGEKGFGYKGSIFHRVIPNFMCQGGDFT 131
            |.|:.:.:     :|.||:||.....|||.:||..|  ..:|: |.|:.|||:|.:||.||||.|
Human    12 PNVYLETS-----MGIIVLELYWKHAPKTCKNFAEL--ARRGY-YNGTKFHRIIKDFMIQGGDPT 68

  Fly   132 NHNGTGGKSIYGNKFPDE-NFELKHTGSGILSMANAGANTNGSQFFICTVKTAWLDNKHVVFGEV 195
            . .|.||.||||.:|.|| :.:||.||:|||:|||||.:|||||||:....|.|||.||.:||.|
Human    69 G-TGRGGASIYGKQFEDELHPDLKFTGAGILAMANAGPDTNGSQFFVTLAPTQWLDGKHTIFGRV 132

  Fly   196 VEGLDVVKKI 205
            .:|:.:|.::
Human   133 CQGIGMVNRV 142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp1	NP_523366.2	cyclophilin_ABH_like	67..225	CDD:238907	67/140 (48%)
PPIL1	NP_057143.1	cyclophilin_SpCYP2_like	15..161	CDD:238903	65/137 (47%)